AU2007302198A1 - Interleukin-1 muteins linked to virus-like particles to treat IL-1 associated diseases - Google Patents

Interleukin-1 muteins linked to virus-like particles to treat IL-1 associated diseases Download PDF

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Publication number
AU2007302198A1
AU2007302198A1 AU2007302198A AU2007302198A AU2007302198A1 AU 2007302198 A1 AU2007302198 A1 AU 2007302198A1 AU 2007302198 A AU2007302198 A AU 2007302198A AU 2007302198 A AU2007302198 A AU 2007302198A AU 2007302198 A1 AU2007302198 A1 AU 2007302198A1
Authority
AU
Australia
Prior art keywords
seq
amino acid
acid sequence
composition
mutein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2007302198A
Other languages
English (en)
Inventor
Martin Bachmann
Gunther Spohn
Alain Tissot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytos Biotechnology AG
Original Assignee
Cytos Biotechnology AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2006/066866 external-priority patent/WO2007039552A1/en
Application filed by Cytos Biotechnology AG filed Critical Cytos Biotechnology AG
Publication of AU2007302198A1 publication Critical patent/AU2007302198A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/18011—Details ssRNA Bacteriophages positive-sense
    • C12N2795/18111—Leviviridae
    • C12N2795/18123—Virus like particles [VLP]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2007302198A 2006-09-28 2007-03-29 Interleukin-1 muteins linked to virus-like particles to treat IL-1 associated diseases Abandoned AU2007302198A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPCT/EP2006/066866 2006-09-28
PCT/EP2006/066866 WO2007039552A1 (en) 2005-09-28 2006-09-28 Interleukin-1 conjugates and uses thereof
PCT/EP2007/053007 WO2008037504A1 (en) 2006-09-28 2007-03-29 Interleukin-1 muteins linked to virus-like particles to treat il-1 associated diseases

Publications (1)

Publication Number Publication Date
AU2007302198A1 true AU2007302198A1 (en) 2008-04-03

Family

ID=38169456

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007302198A Abandoned AU2007302198A1 (en) 2006-09-28 2007-03-29 Interleukin-1 muteins linked to virus-like particles to treat IL-1 associated diseases

Country Status (4)

Country Link
EP (1) EP2066347A1 (de)
AU (1) AU2007302198A1 (de)
CA (1) CA2664418A1 (de)
WO (1) WO2008037504A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1773303A2 (de) 2004-05-25 2007-04-18 Chimeracore, Inc. Selbstmontierendes nanopartikel-wirkstofffreisetzungssystem
JP2009533350A (ja) 2006-04-07 2009-09-17 キメロス， インコーポレイテッド Ｂ細胞悪性疾患を処置するための組成物および方法
BRPI0909096A2 (pt) * 2008-03-05 2015-12-01 Cytos Biotechnology Ag uso de conjugados de interleicna-1 no tratamento de diabetes
WO2010120874A2 (en) 2009-04-14 2010-10-21 Chimeros, Inc. Chimeric therapeutics, compositions, and methods for using same
EP2475397A1 (de) * 2009-09-10 2012-07-18 Cytos Biotechnology AG Verwendung von interleukin-1-beta-mutein-konjugaten zur behandlung von diabetes
EP2747774A4 (de) 2011-09-09 2015-02-11 Biomed Realty L P Verfahren und zusammensetzungen zur kontrolle einer virusproteinassemblierung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0460052T3 (da) * 1989-02-27 1999-03-08 New England Medical Center Inc Inhibitorer af IL-1's biologiske aktivitet
DE60040740D1 (de) * 1999-12-03 2008-12-18 Celltech Chiroscience Ltd VERWENDUNG OF INTERLEUkIN-1 MUTEIN ALS IMPFSTOFFADJUVANS
EP1532167B1 (de) * 2002-07-17 2012-01-25 Cytos Biotechnology AG Molekulare antigen-anordnung durch verwendung eines virus-ähnlichen partikels vom virus ap205

Also Published As

Publication number Publication date
EP2066347A1 (de) 2009-06-10
WO2008037504A1 (en) 2008-04-03
CA2664418A1 (en) 2008-04-03

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BACHMANN et al. Patent 2717108 Summary

Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period