AU2003299361A1 - Novel chiral compounds derived from hexanoic acid esters, method and intermediate chemicals for the preparation and use thereof for synthesis of 2-(bromomethyl)2-ethyl hexanoic chiral acid - Google Patents

Novel chiral compounds derived from hexanoic acid esters, method and intermediate chemicals for the preparation and use thereof for synthesis of 2-(bromomethyl)2-ethyl hexanoic chiral acid

Info

Publication number
AU2003299361A1
AU2003299361A1 AU2003299361A AU2003299361A AU2003299361A1 AU 2003299361 A1 AU2003299361 A1 AU 2003299361A1 AU 2003299361 A AU2003299361 A AU 2003299361A AU 2003299361 A AU2003299361 A AU 2003299361A AU 2003299361 A1 AU2003299361 A1 AU 2003299361A1
Authority
AU
Australia
Prior art keywords
hexanoic
chiral
bromomethyl
synthesis
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003299361A
Inventor
Veronique Crocq-Stuerga
Patrick Roussel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of AU2003299361A1 publication Critical patent/AU2003299361A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/15—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing halogen
    • C07C53/19—Acids containing three or more carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/34—Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62—Halogen-containing esters
    • C07C69/63—Halogen-containing esters of saturated acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003299361A 2002-12-20 2003-12-19 Novel chiral compounds derived from hexanoic acid esters, method and intermediate chemicals for the preparation and use thereof for synthesis of 2-(bromomethyl)2-ethyl hexanoic chiral acid Abandoned AU2003299361A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0216229A FR2849024B1 (en) 2002-12-20 2002-12-20 NOVEL CHIRAL COMPOUNDS DERIVED FROM HEXANOIC ACID ESTERS, PROCESS AND PREPARATION INTERMEDIATES, USE IN THE SYNTHESIS OF CHIRAL 2- (BROMOMETHYL) 2-ETHYL HEXANOIC ACID
FR0216229 2002-12-20
PCT/FR2003/003812 WO2004058678A1 (en) 2002-12-20 2003-12-19 Novel chiral compounds derived from hexanoic acid esters, method and intermediate chemicals for the preparation and use thereof for synthesis of 2-(bromomethyl)2-ethyl hexanoic chiral acid

Publications (1)

Publication Number Publication Date
AU2003299361A1 true AU2003299361A1 (en) 2004-07-22

Family

ID=32406228

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003299361A Abandoned AU2003299361A1 (en) 2002-12-20 2003-12-19 Novel chiral compounds derived from hexanoic acid esters, method and intermediate chemicals for the preparation and use thereof for synthesis of 2-(bromomethyl)2-ethyl hexanoic chiral acid

Country Status (10)

Country Link
EP (1) EP1578714B1 (en)
JP (1) JP2006510715A (en)
AU (1) AU2003299361A1 (en)
BR (1) BR0317527A (en)
CA (1) CA2510365A1 (en)
DE (1) DE60315510T2 (en)
ES (1) ES2289357T3 (en)
FR (1) FR2849024B1 (en)
MX (1) MXPA05006060A (en)
WO (1) WO2004058678A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1831154E (en) * 2004-06-21 2010-02-19 Warner Lambert Co Preparation of pregabalin and related compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2250422A (en) * 1938-07-30 1941-07-22 Lilly Co Eli Alkyl-crotyl barbituric acids and their salts
GB9800428D0 (en) * 1998-01-10 1998-03-04 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
DE60315510T2 (en) 2008-04-24
ES2289357T3 (en) 2008-02-01
BR0317527A (en) 2005-11-22
CA2510365A1 (en) 2004-07-15
EP1578714B1 (en) 2007-08-08
DE60315510D1 (en) 2007-09-20
FR2849024B1 (en) 2007-11-02
FR2849024A1 (en) 2004-06-25
MXPA05006060A (en) 2005-08-16
EP1578714A1 (en) 2005-09-28
JP2006510715A (en) 2006-03-30
WO2004058678A1 (en) 2004-07-15

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase