AU2003292882A1 - Thrombin from venom of agkistrodon acutus used as drugs for the treatment of haemorrhage - Google Patents

Thrombin from venom of agkistrodon acutus used as drugs for the treatment of haemorrhage

Info

Publication number
AU2003292882A1
AU2003292882A1 AU2003292882A AU2003292882A AU2003292882A1 AU 2003292882 A1 AU2003292882 A1 AU 2003292882A1 AU 2003292882 A AU2003292882 A AU 2003292882A AU 2003292882 A AU2003292882 A AU 2003292882A AU 2003292882 A1 AU2003292882 A1 AU 2003292882A1
Authority
AU
Australia
Prior art keywords
haemorrhage
venom
thrombin
drugs
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003292882A
Inventor
Zhong Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LIN WENHONG
LIU XIANYING
Original Assignee
LIN WENHONG
LIU XIANYING
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LIN WENHONG, LIU XIANYING filed Critical LIN WENHONG
Publication of AU2003292882A1 publication Critical patent/AU2003292882A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6429—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2003292882A 2003-08-14 2003-12-08 Thrombin from venom of agkistrodon acutus used as drugs for the treatment of haemorrhage Abandoned AU2003292882A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNB031401546A CN1218747C (en) 2003-08-14 2003-08-14 Medicinal use of agkistrodon acutus thrombase for treating hemorrhagic disease
CN03140154.6 2003-08-14
PCT/CN2003/001048 WO2005017139A1 (en) 2003-08-14 2003-12-08 Thrombin from venom of agkistrodon acutus used as drugs for the treatment of haemorrhage

Publications (1)

Publication Number Publication Date
AU2003292882A1 true AU2003292882A1 (en) 2005-03-07

Family

ID=34155227

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003292882A Abandoned AU2003292882A1 (en) 2003-08-14 2003-12-08 Thrombin from venom of agkistrodon acutus used as drugs for the treatment of haemorrhage

Country Status (3)

Country Link
CN (1) CN1218747C (en)
AU (1) AU2003292882A1 (en)
WO (1) WO2005017139A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100494366C (en) 2006-10-19 2009-06-03 康辰医药股份有限公司 Thrombin
CN101358184A (en) * 2008-09-27 2009-02-04 康辰医药股份有限公司 Hemocoagulase agkistrodon
CN102757948B (en) * 2012-05-28 2014-02-05 广东瑞昇药业有限公司 Haemocoagulase agkistrodon and separation method thereof
CN103893770B (en) * 2012-12-26 2018-06-19 李和伟 A kind of freeze-drying excipient preparation and preparation method thereof
CN105535949A (en) * 2015-12-28 2016-05-04 重庆骑士医院 Method for fermenting traditional Chinese medicine with batroxobin yeast
WO2019010602A1 (en) * 2017-07-10 2019-01-17 中山大学 Expression method for haemocoagulase acutus recombinant protein

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1060806C (en) * 1997-11-12 2001-01-17 中国科学院上海生物化学研究所 Gene sequence of fibrin ferment of Agkistrodon acutus snakes
CN1151254C (en) * 2001-01-08 2004-05-26 中国药科大学 Structure and purification of venin-class thrombase for preventing and curing thrombotic diseases
CN1159438C (en) * 2001-04-29 2004-07-28 中国科学院昆明动物研究所 Ahylysantinfarctase thrombase and its production process
CN1159437C (en) * 2001-04-29 2004-07-28 中国科学院昆明动物研究所 Ahylysantinfarctase thrombase and its production process

Also Published As

Publication number Publication date
CN1488399A (en) 2004-04-14
WO2005017139A1 (en) 2005-02-24
CN1218747C (en) 2005-09-14

Similar Documents

Publication Publication Date Title
AU2002349352A1 (en) Keratinocytes which may be used as biologically active substances for the treatment of wounds
HUP0600341A2 (en) Keratinocytes which may be used as biologically active substances for the treatment of wounds
WO2004006858A3 (en) Compounds, compositions, and methods employing same
AU2002342613A1 (en) Treatment for wounds
AU2003280298A1 (en) Methods for the biological treatment of gas
AU2003258145A1 (en) Substituted phenylindoles for the treatment of hiv
AU2003303926A1 (en) Ceramics and methods of making the same
AU2003235307A1 (en) Crystal of glucokinase protein, and method for drug design using the crystal
AU2003255612A1 (en) Novel multimeric molecules, the preparation method thereof and use of same for the preparation of medicaments
AU2003241599A1 (en) Compositions and methods for the treatment of hemophilia a
AU2003292882A1 (en) Thrombin from venom of agkistrodon acutus used as drugs for the treatment of haemorrhage
AU2003291886A1 (en) Thiophenederivatives for the treatment of flavivirus infections
AU2003206367A1 (en) Technical field of the invention
IL173631A0 (en) Crystal forms of 1-methyl carbapenem, processes for the preparation thereof and pharmaceutical compositions containing the same
AU2003220026A1 (en) Methods and compositions for the treatment of ischemia
AU2003226687A1 (en) Arrangement for the operation of field devices
AU2003295163A1 (en) Composition for the treatment of hiv or aids
AU2003263332A1 (en) Wound dressings for the treatment of wound infection
AU2003279592A1 (en) Intravitreally-injectable solution for the treatment of vitreous haemorrhages
AU2003240174A1 (en) Compositions for the treatment of edematous-firbrosclerotic panniculopathy
AU2003259689A1 (en) 3-imino-2-indolones for the treatment of depression and/or anxiety
AU2003267907A1 (en) Prothrombin purification
AU2003208809A1 (en) Treatment of neuroblastoma
AU2003295134A1 (en) Material for the removal of pollutants
AU2003902586A0 (en) Treatment of burns

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase