AU2003291245A1 - 4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (cml) - Google Patents

4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (cml)

Info

Publication number
AU2003291245A1
AU2003291245A1 AU2003291245A AU2003291245A AU2003291245A1 AU 2003291245 A1 AU2003291245 A1 AU 2003291245A1 AU 2003291245 A AU2003291245 A AU 2003291245A AU 2003291245 A AU2003291245 A AU 2003291245A AU 2003291245 A1 AU2003291245 A1 AU 2003291245A1
Authority
AU
Australia
Prior art keywords
quinolinecarbonitriles
cml
anilino
treatment
myelogenous leukemia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003291245A
Other versions
AU2003291245A8 (en
Inventor
Kim Timothy Arndt
Frank Boschelli
Jennifer Michele Golas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Publication of AU2003291245A1 publication Critical patent/AU2003291245A1/en
Publication of AU2003291245A8 publication Critical patent/AU2003291245A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003291245A 2003-11-06 2003-11-06 4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (cml) Abandoned AU2003291245A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2003/035322 WO2005047259A1 (en) 2003-11-06 2003-11-06 4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (cml)

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2004289243A Division AU2004289243B2 (en) 2003-11-06 2004-11-03 4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (CML)

Publications (2)

Publication Number Publication Date
AU2003291245A1 true AU2003291245A1 (en) 2004-06-06
AU2003291245A8 AU2003291245A8 (en) 2005-06-06

Family

ID=34589300

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003291245A Abandoned AU2003291245A1 (en) 2003-11-06 2003-11-06 4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (cml)

Country Status (2)

Country Link
AU (1) AU2003291245A1 (en)
WO (1) WO2005047259A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2449197T5 (en) * 2005-07-01 2022-04-28 Wyeth Llc Crystalline forms of 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile and methods of preparing the same
US20100152198A1 (en) * 2006-04-07 2010-06-17 Manley Paul W Use of c-src inhibitors in combination with a pyrimidylaminobenzamide compound for the treatment of leukemia
CN102070524A (en) * 2011-01-12 2011-05-25 无锡好芳德药业有限公司 Method for preparing 3-cyano-4-halogenated quinoline derivatives
US9776970B2 (en) 2014-02-20 2017-10-03 Apotex Inc. Bosutinib forms and preparation methods thereof
WO2017029584A1 (en) * 2015-08-19 2017-02-23 Sun Pharmaceutical Industries Limited Amorphous form of bosutinib

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA73073C2 (en) * 1997-04-03 2005-06-15 Уайт Холдінгз Корпорейшн Substituted 3-cyan chinolines
AR035851A1 (en) * 2000-03-28 2004-07-21 Wyeth Corp 3-CIANOQUINOLINS, 3-CIANO-1,6-NAFTIRIDINES AND 3-CIANO-1,7-NAFTIRIDINS AS INHIBITORS OF PROTEIN KINASES

Also Published As

Publication number Publication date
AU2003291245A8 (en) 2005-06-06
WO2005047259A1 (en) 2005-05-26

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Legal Events

Date Code Title Description
TH Corrigenda

Free format text: IN VOL 19, NO 28, PAGE(S) 1861 UNDER THE HEADING APPLICATIONS OPI - NAME INDEX UNDER THE NAME WYETH, APPLICATION NO. 2003291245, UNDER INID (43) CORRECT THE DATE TO READ 06.06.2005

MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase