AU2003291141A8 - 5-nitroso-6-piperazinyl-pyrimidine derivatives for treating ischemia - Google Patents

5-nitroso-6-piperazinyl-pyrimidine derivatives for treating ischemia

Info

Publication number
AU2003291141A8
AU2003291141A8 AU2003291141A AU2003291141A AU2003291141A8 AU 2003291141 A8 AU2003291141 A8 AU 2003291141A8 AU 2003291141 A AU2003291141 A AU 2003291141A AU 2003291141 A AU2003291141 A AU 2003291141A AU 2003291141 A8 AU2003291141 A8 AU 2003291141A8
Authority
AU
Australia
Prior art keywords
nitroso
piperazinyl
pyrimidine derivatives
treating ischemia
ischemia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
AU2003291141A
Other versions
AU2003291141A1 (en
Inventor
Edward J Hessler
Luis H Toledo
Harold A Karnes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EPCELLON Inc
Original Assignee
EPCELLON Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EPCELLON Inc filed Critical EPCELLON Inc
Publication of AU2003291141A1 publication Critical patent/AU2003291141A1/en
Publication of AU2003291141A8 publication Critical patent/AU2003291141A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003291141A 2002-12-03 2003-11-21 5-nitroso-6-piperazinyl-pyrimidine derivatives for treating ischemia Abandoned AU2003291141A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43054502P 2002-12-03 2002-12-03
US60/430,545 2002-12-03
PCT/US2003/037341 WO2004050639A2 (en) 2002-12-03 2003-11-21 5-nitroso-6-piperazinyl-pyrimidine derivatives for treating ischemia

Publications (2)

Publication Number Publication Date
AU2003291141A1 AU2003291141A1 (en) 2004-06-23
AU2003291141A8 true AU2003291141A8 (en) 2004-06-23

Family

ID=32469490

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003291141A Abandoned AU2003291141A1 (en) 2002-12-03 2003-11-21 5-nitroso-6-piperazinyl-pyrimidine derivatives for treating ischemia

Country Status (2)

Country Link
AU (1) AU2003291141A1 (en)
WO (1) WO2004050639A2 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU214331B (en) * 1992-06-17 1998-03-02 Gyógyszerkutató Intézet Kft. Methods for producing piperazine and homopiperazine derivatives and pharmaceutical compositions containing them
HUT76265A (en) * 1995-10-19 1997-07-28 Gyogyszerkutato Intezet Pyrimidine derivatives, pharmaceutical compositions containing them, process for producing them and their use
FR2787447B1 (en) * 1998-12-18 2001-03-23 Centre Nat Rech Scient NOVEL MELATONIN DERIVATIVES AND MEDICINAL PRODUCT COMPRISING SUCH DERIVATIVES
US6359182B1 (en) * 2000-10-26 2002-03-19 Duke University C-nitroso compounds and use thereof

Also Published As

Publication number Publication date
AU2003291141A1 (en) 2004-06-23
WO2004050639A3 (en) 2004-12-09
WO2004050639A2 (en) 2004-06-17

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase