AU2003289631A1 - A recombinant adenovirus relating gene vaccine used to therapy and prevent alzheimers disease, and use thereof - Google Patents
A recombinant adenovirus relating gene vaccine used to therapy and prevent alzheimers disease, and use thereofInfo
- Publication number
- AU2003289631A1 AU2003289631A1 AU2003289631A AU2003289631A AU2003289631A1 AU 2003289631 A1 AU2003289631 A1 AU 2003289631A1 AU 2003289631 A AU2003289631 A AU 2003289631A AU 2003289631 A AU2003289631 A AU 2003289631A AU 2003289631 A1 AU2003289631 A1 AU 2003289631A1
- Authority
- AU
- Australia
- Prior art keywords
- therapy
- prevent
- recombinant adenovirus
- alzheimers disease
- vaccine used
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 208000024827 Alzheimer disease Diseases 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 241000701161 unidentified adenovirus Species 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Animal Behavior & Ethology (AREA)
- Hospice & Palliative Care (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN02154703.3 | 2002-11-29 | ||
CNB021547033A CN100450551C (en) | 2002-11-29 | 2002-11-29 | Recombinated adeno-associated virus genes vaccine for prevention and cure of Alzheimer disease and use thereof |
PCT/CN2003/001019 WO2004050876A1 (en) | 2002-11-29 | 2003-12-01 | A recombinant adenovirus relating gene vaccine used to therapy and prevent alzheimers disease, and use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2003289631A1 true AU2003289631A1 (en) | 2004-06-23 |
AU2003289631A8 AU2003289631A8 (en) | 2004-06-23 |
Family
ID=32400078
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2003289631A Abandoned AU2003289631A1 (en) | 2002-11-29 | 2003-12-01 | A recombinant adenovirus relating gene vaccine used to therapy and prevent alzheimers disease, and use thereof |
Country Status (3)
Country | Link |
---|---|
CN (1) | CN100450551C (en) |
AU (1) | AU2003289631A1 (en) |
WO (1) | WO2004050876A1 (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10303974A1 (en) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid β (1-42) oligomers, process for their preparation and their use |
JP4888876B2 (en) * | 2003-06-13 | 2012-02-29 | 田平 武 | Recombinant adeno-associated virus vector for the treatment of Alzheimer's disease |
WO2005014041A2 (en) * | 2003-07-24 | 2005-02-17 | Novartis Ag | Use of an amyloid beta dna vaccine for the treatment and/or prevention of amyloid diseases |
EP1828251B1 (en) * | 2004-10-05 | 2012-09-26 | Janssen Alzheimer Immunotherapy | Methods and compositions for improving recombinant protein production |
KR101434935B1 (en) | 2005-11-30 | 2014-10-01 | 애브비 인코포레이티드 | Monoclonal antibodies against amyloid beta protein and uses thereof |
JP5475994B2 (en) | 2005-11-30 | 2014-04-16 | アッヴィ・インコーポレイテッド | Anti-Aβ globulomer antibody, antigen-binding portion thereof, corresponding hybridoma, nucleic acid, vector, host cell, method for producing said antibody, composition comprising said antibody, use of said antibody and method of using said antibody. |
US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
US20100311767A1 (en) | 2007-02-27 | 2010-12-09 | Abbott Gmbh & Co. Kg | Method for the treatment of amyloidoses |
CN101392027B (en) * | 2008-07-03 | 2012-04-25 | 浙江大学 | Fusion protein for treating alzheimer's disease and preparation method thereof |
JPWO2010050585A1 (en) * | 2008-10-31 | 2012-03-29 | ディナベック株式会社 | Alzheimer's disease treatment vector |
CN104744591B (en) | 2010-04-15 | 2022-09-27 | Abbvie德国有限责任两合公司 | Amyloid beta binding proteins |
CA2808187A1 (en) | 2010-08-14 | 2012-02-23 | Abbvie Inc. | Amyloid-beta binding proteins |
CN103071160A (en) * | 2011-10-24 | 2013-05-01 | 四川百利药业有限责任公司 | Gene vaccine for Alzheimer's disease |
JP2017521092A (en) * | 2014-05-16 | 2017-08-03 | ヴィトルヴィアン バイオメディカル, インク.Vitruvian Biomedical, Inc. | Diagnostic testing and treatment / prevention of Alzheimer's disease |
CN107034198B (en) | 2015-07-15 | 2021-03-09 | 长春百克生物科技股份公司 | Chimeric norovirus P particle and preparation and application thereof |
CN105597108A (en) * | 2015-12-30 | 2016-05-25 | 广州凯拓生物科技开发有限公司 | Construction and application of Complexin 1/2 overexpression recombinant vector |
CN113862346B (en) * | 2021-09-26 | 2023-07-07 | 北京大学 | Application of long-chain non-coding RNA in treatment of Alzheimer disease |
CN116327904B (en) * | 2022-08-02 | 2024-05-28 | 深圳源兴基因技术有限公司 | Recombinant adeno-associated virus gene vaccine for treating and preventing Alzheimer disease and application thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI239847B (en) * | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
EP1404368B1 (en) * | 2001-06-07 | 2009-12-09 | Wyeth Holdings Corporation | Mutant forms of cholera holotoxin as an adjuvant |
-
2002
- 2002-11-29 CN CNB021547033A patent/CN100450551C/en not_active Expired - Fee Related
-
2003
- 2003-12-01 WO PCT/CN2003/001019 patent/WO2004050876A1/en not_active Application Discontinuation
- 2003-12-01 AU AU2003289631A patent/AU2003289631A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN1504240A (en) | 2004-06-16 |
WO2004050876A1 (en) | 2004-06-17 |
CN100450551C (en) | 2009-01-14 |
AU2003289631A8 (en) | 2004-06-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase | ||
TH | Corrigenda |
Free format text: IN VOL 18, NO 29, PAGE(S) 7783 UNDER THE HEADING APPLICATIONS OPI - NAME INDEX UNDER THE NAME AGTC GENE TECHNOLOGY COMPANY LTD., APPLICATION NO. 2003289631, UNDER INID (71) CORRECT THE NAME TO READ INSTITUTE OF BASIC MEDICAL SCIENCES,CHINESE ACADEMY OF MEDICAL SCIENCES; INSTITUTE OF LABORATORY ANIMALS,CHINESE ACADEMY OF MEDICAL SCIENCES; AGTC GENE TECHNOLOGY COMPANY LTD. |