AU2003287265A1 - Cyclooxygenase-2 inhibitory withanolide compositions and method - Google Patents

Cyclooxygenase-2 inhibitory withanolide compositions and method

Info

Publication number
AU2003287265A1
AU2003287265A1 AU2003287265A AU2003287265A AU2003287265A1 AU 2003287265 A1 AU2003287265 A1 AU 2003287265A1 AU 2003287265 A AU2003287265 A AU 2003287265A AU 2003287265 A AU2003287265 A AU 2003287265A AU 2003287265 A1 AU2003287265 A1 AU 2003287265A1
Authority
AU
Australia
Prior art keywords
cyclooxygenase
inhibitory
withanolide
compositions
withanolide compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003287265A
Inventor
Bolleddula Jayaprakasam
Muraleedharan G. Nair
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Michigan State University MSU
Original Assignee
Michigan State University MSU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Michigan State University MSU filed Critical Michigan State University MSU
Publication of AU2003287265A1 publication Critical patent/AU2003287265A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2003287265A 2002-11-14 2003-10-29 Cyclooxygenase-2 inhibitory withanolide compositions and method Abandoned AU2003287265A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/294,106 US7195784B2 (en) 2002-11-14 2002-11-14 Cyclooxygenase-2 inhibitory withanolide compositions and method
US10/294,106 2002-11-14
PCT/US2003/034449 WO2004043478A1 (en) 2002-11-14 2003-10-29 Cyclooxygenase-2 inhibitory withanolide compositions and method

Publications (1)

Publication Number Publication Date
AU2003287265A1 true AU2003287265A1 (en) 2004-06-03

Family

ID=32296899

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003287265A Abandoned AU2003287265A1 (en) 2002-11-14 2003-10-29 Cyclooxygenase-2 inhibitory withanolide compositions and method

Country Status (9)

Country Link
US (8) US7195784B2 (en)
EP (1) EP1562618A4 (en)
JP (1) JP2006508963A (en)
KR (2) KR100679367B1 (en)
CN (1) CN1711100A (en)
AU (1) AU2003287265A1 (en)
CA (1) CA2503006C (en)
MX (1) MXPA05005084A (en)
WO (1) WO2004043478A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050266100A1 (en) * 2004-03-30 2005-12-01 Council Of Scientific And Industrial Research Rafi Marg Process isolation of withaferin-A from plant materials and products therefrom
US7108870B2 (en) * 2004-04-13 2006-09-19 Council Of Scientific & Industrial Research Process for isolation of withaferin-A from plant materials and products therefrom
US7951845B2 (en) * 2006-01-19 2011-05-31 The Regents Of The University Of Michigan Composition and method of treating hearing loss
USRE46372E1 (en) 2006-01-19 2017-04-25 The Regents Of The Univerity Of Michigan Method for treating hearing loss
US9919008B2 (en) 2006-01-19 2018-03-20 The Regents Of The University Of Michigan Method for treating age-related hearing loss (ARHL)
US20090155390A1 (en) * 2006-01-19 2009-06-18 Miller Josef M Composition and method of treating temporary and permanent hearing loss
US8338397B2 (en) 2006-01-19 2012-12-25 The Regents Of The University Of Michigan Composition and method of treating side effects from antibiotic treatment
US9770433B2 (en) 2006-01-19 2017-09-26 The Regents Of The University Of Michigan Composition and method for treating tinnitus
US8927528B2 (en) 2006-01-19 2015-01-06 The Regents Of The University Of Michigan Composition for treating hearing loss
US10238599B2 (en) 2006-01-19 2019-03-26 The Regents Of The University Of Michigan Composition and method for treating congenital cytomegalovirus induced hearing loss
US9889156B2 (en) 2006-01-19 2018-02-13 The Regents Of The University Of Michigan Method for treating noise-induced hearing loss (NIHL)
US8283323B2 (en) * 2006-03-13 2012-10-09 University Of Kentucky Research Foundation Withanolide compounds as inhibitors of fibrosis and identification of molecular targets for anti-fibrotic drug development
US8735178B2 (en) * 2006-03-27 2014-05-27 University Of Kentucky Research Foundation Withanolides, probes and binding targets and methods of use thereof
DE102006023261A1 (en) * 2006-05-18 2007-11-22 Bayer Materialscience Ag Process for the production of chlorine from hydrogen chloride and oxygen
WO2008101109A1 (en) * 2007-02-14 2008-08-21 University Of Kentucky Research Foundation Withanolides, probes and binding targets and methods of use thereof
JP5704484B2 (en) * 2008-03-06 2015-04-22 独立行政法人産業技術総合研究所 Composition comprising Ashwagandha leaf water extract as active ingredient and method for producing the same
EP2318025A2 (en) * 2008-07-28 2011-05-11 National Brain Research Centre Withania somnifera plant extract and method of preparation thereof
WO2010030395A2 (en) * 2008-09-15 2010-03-18 Whitehead Institute For Biomedical Research Withaferin a analogs and uses thereof
WO2010053655A2 (en) * 2008-11-07 2010-05-14 University Of Kansas Therapeutic methods with withaferin a and analogs
US20120070521A1 (en) * 2009-05-22 2012-03-22 Bio-Ved Pharmaceuticals, PVT., Ltd. Method of extraction from withania somnifera and one or more fractions containing pharmacologically active ingredients obtained therefrom
WO2011119625A1 (en) * 2010-03-22 2011-09-29 Fred Hutchinson Cancer Research Center D. innoxia withanolides with specific anti-cancer activities
CN103877383A (en) * 2014-03-26 2014-06-25 陈运平 Traditional Chinese medicine preparation for treating bronchial asthma with syndrome of intermin-gled phlegm and qi
CN108392484B (en) * 2018-02-06 2021-04-13 贵州省食品药品检验所 Application of steroid compound in preparation of medicine for preventing or treating gastric ulcer and complications thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD152133A1 (en) * 1980-07-23 1981-11-18 Guenter Adam METHOD FOR OBTAINING WITHANOLIDGLYCOSIDES
JPS643626A (en) * 1987-06-26 1989-01-09 Matsushita Electric Ind Co Ltd Production of liquid crystal display device
US5494668A (en) * 1994-07-11 1996-02-27 Patwardhan; Bhushan Method of treating musculoskeletal disease and a novel composition therefor
ZA95908B (en) * 1995-02-06 1995-10-13 Joshi Yeshwant Dr Kashinath A synergistic formulation for treatment of rheumatic diseases
JPH1036216A (en) * 1996-07-22 1998-02-10 Pola Chem Ind Inc Skin cosmetic
US5683698A (en) * 1996-08-02 1997-11-04 New England Deaconess Hospital Formulation for alleviating symptoms associated with arthritis
JPH1045541A (en) * 1996-08-06 1998-02-17 Pola Chem Ind Inc Trichogen
JP4788039B2 (en) * 1999-05-10 2011-10-05 日本新薬株式会社 Composition for recovery of reduced reproductive function
JP2001005895A (en) * 1999-06-21 2001-01-12 Hitachi Ltd Electronic money replenishing system to electronic money card of ic card type
JP2002145794A (en) * 2000-08-31 2002-05-22 Nippon Kayaku Co Ltd Antiarthritic or antirheumatic preparation, food or feed
JP2002187846A (en) * 2000-10-12 2002-07-05 Nippon Kayaku Co Ltd Composition, food products, antiarthritic agent and antirheumatic agent or feed including the same
US20040033273A1 (en) * 2001-02-14 2004-02-19 Ayurcore, Inc. Withasol and methods of use
US6387416B1 (en) * 2001-04-05 2002-05-14 Thomas Newmark Anti-Inflammatory herbal composition and method of use
AU2002246308A1 (en) * 2002-02-14 2003-09-04 Dalmia Centre For Research And Development Herbal formulation for treating attention defienciency disorder (add/adht) and process for preparation

Also Published As

Publication number Publication date
US7270836B2 (en) 2007-09-18
EP1562618A1 (en) 2005-08-17
US20060246159A1 (en) 2006-11-02
CN1711100A (en) 2005-12-21
US7208182B2 (en) 2007-04-24
US20060251740A1 (en) 2006-11-09
US20060246160A1 (en) 2006-11-02
US7141253B2 (en) 2006-11-28
US20040258781A1 (en) 2004-12-23
JP2006508963A (en) 2006-03-16
CA2503006A1 (en) 2004-05-27
US20060247182A1 (en) 2006-11-02
KR100687380B1 (en) 2007-04-16
US7195784B2 (en) 2007-03-27
US7211277B2 (en) 2007-05-01
MXPA05005084A (en) 2005-07-25
US20060188592A1 (en) 2006-08-24
US7264833B2 (en) 2007-09-04
KR20060111739A (en) 2006-10-27
US20060246158A1 (en) 2006-11-02
EP1562618A4 (en) 2009-07-22
CA2503006C (en) 2008-01-08
WO2004043478A1 (en) 2004-05-27
US20040096524A1 (en) 2004-05-20
KR20050075004A (en) 2005-07-19
US7264832B2 (en) 2007-09-04
US7264831B2 (en) 2007-09-04
KR100679367B1 (en) 2007-02-07

Similar Documents

Publication Publication Date Title
AU2003287265A1 (en) Cyclooxygenase-2 inhibitory withanolide compositions and method
AU2003262747A1 (en) Compounds, compositions, and methods
AU2003236527A1 (en) Compounds, compositions, and methods
AU2003265242A1 (en) Compounds, compositions, and methods
AU2003243531A1 (en) Fermentation methods and compositions
AU2003202263A1 (en) Roh-kinase inhibitors
AU2003256876A1 (en) Method of color-matching
AU2003270015A1 (en) Compounds, compositions, and methods
EP1369196B8 (en) Slide saw and method of using the same
AU2003226094A1 (en) Compounds and methods
AU2003299612A1 (en) Compounds, compositions and methods
AU2003252246A1 (en) Herbicide compositions and weedkilling method using the same
AU2003256805A1 (en) Compounds compositions and methods
AU2003238042A1 (en) Cyclooxygenase-2 inhibitors
AU2003249683A1 (en) Nf-:b inhibitors
AU2003277596A1 (en) Method of deuterization
AU2003266815A1 (en) Immunoglobulin compositions and methods
AU2003276905A1 (en) A conductive composition and method of using the same
AU2003290507A1 (en) Compounds, compositions and methods
AU2003258070A1 (en) Electrodionization method
AU2003277079A1 (en) Compounds, compositions, and methods
AU2003222058A1 (en) Materials and methods for inhibiting wip-1
AUPS096002A0 (en) Method of construction
AU2003295574A1 (en) Method and compositions for temporarily incapaciting subjets
AU2003300031A1 (en) Compounds, compositions, and methods

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase