AU2003283500A1 - 1,4-diazabicyclo(3.2.2)nonanecarboxamide derivatives, preparation and therapeutic use thereof related to malfunction of nicotinic receptors - Google Patents

1,4-diazabicyclo(3.2.2)nonanecarboxamide derivatives, preparation and therapeutic use thereof related to malfunction of nicotinic receptors

Info

Publication number
AU2003283500A1
AU2003283500A1 AU2003283500A AU2003283500A AU2003283500A1 AU 2003283500 A1 AU2003283500 A1 AU 2003283500A1 AU 2003283500 A AU2003283500 A AU 2003283500A AU 2003283500 A AU2003283500 A AU 2003283500A AU 2003283500 A1 AU2003283500 A1 AU 2003283500A1
Authority
AU
Australia
Prior art keywords
nonanecarboxamide
diazabicyclo
malfunction
derivatives
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003283500A
Other languages
English (en)
Other versions
AU2003283500A8 (en
Inventor
Frederic Galli
Patrick Lardenois
Odile Leclerc
Alistair Lochead
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Publication of AU2003283500A1 publication Critical patent/AU2003283500A1/en
Publication of AU2003283500A8 publication Critical patent/AU2003283500A8/xx
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AU2003283500A 2002-10-08 2003-10-06 1,4-diazabicyclo(3.2.2)nonanecarboxamide derivatives, preparation and therapeutic use thereof related to malfunction of nicotinic receptors Abandoned AU2003283500A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0212500A FR2845388B1 (fr) 2002-10-08 2002-10-08 Derives de 1,4-diazabicyclo[3.2.2]nonanecarboxamides, leur preparation et leur application en therapeutique
FR02/12500 2002-10-08
PCT/FR2003/002929 WO2004033456A2 (fr) 2002-10-08 2003-10-06 Derives de 1,4-diazabicyclo[3.2.2]nonanecarboxamides, leur preparation et leur application en therapeutique ayant trait au dysfonctionnement des recepteurs nicotiniques

Publications (2)

Publication Number Publication Date
AU2003283500A1 true AU2003283500A1 (en) 2004-05-04
AU2003283500A8 AU2003283500A8 (en) 2004-05-04

Family

ID=32011522

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003283500A Abandoned AU2003283500A1 (en) 2002-10-08 2003-10-06 1,4-diazabicyclo(3.2.2)nonanecarboxamide derivatives, preparation and therapeutic use thereof related to malfunction of nicotinic receptors

Country Status (9)

Country Link
EP (1) EP1575960B1 (enExample)
JP (1) JP4537853B2 (enExample)
AR (1) AR041527A1 (enExample)
AT (1) ATE425980T1 (enExample)
AU (1) AU2003283500A1 (enExample)
DE (1) DE60326757D1 (enExample)
FR (1) FR2845388B1 (enExample)
TW (1) TWI320413B (enExample)
WO (1) WO2004033456A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2405594T3 (es) 2002-09-25 2013-05-31 Memory Pharmaceuticals Corporation Idazoles, benzotiazoles y benzisotiazoles, y preparación y usos de los mismos
EP1697378B1 (en) 2003-12-22 2007-11-21 Memory Pharmaceuticals Corporation Indoles, 1h-indazoles, 1,2-benzisoxazoles, and 1,2-benzisothiazoles, and preparation and uses thereof
FR2865208B1 (fr) 2004-01-16 2009-01-16 Sanofi Synthelabo Derives de 1,4-diazabicyclo[3.2.1]octanecarboxmique, leur preparation et leur application en therapeutique
BRPI0508771A (pt) 2004-03-25 2007-08-14 Memory Pharm Corp indazóis, benzotiazóis, benzoisotiazóis, benzisoxazóis, e a preparação e usos dos mesmos
US7488737B2 (en) 2004-04-22 2009-02-10 Memory Pharmaceutical Corporation Indoles, 1H-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof
KR20070015607A (ko) * 2004-05-07 2007-02-05 메모리 파마슈티칼스 코포레이션 1ｈ-인다졸, 벤조티아졸, 1,2-벤조이속사졸,1,2-벤조이소티아졸, 및 크로몬 및 그의 제조법 및 용도
ATE412651T1 (de) 2004-06-09 2008-11-15 Glaxo Group Ltd Pyrrolopyridinderivate
RU2418797C2 (ru) 2004-12-22 2011-05-20 Мемори Фармасьютиклз Корпорейшн Лиганды никотинового рецептора альфа-7, их получение и применение
JP2009514980A (ja) * 2005-11-09 2009-04-09 メモリー・ファーマシューティカルズ・コーポレイション １ｈ−インダゾール類、ベンゾチアゾール類、１，２−ベンゾイソオキサゾール類、１，２−ベンゾイソチアゾール類、および／クロモン類と、それらの製造と用途
EP1842541A1 (en) * 2006-03-29 2007-10-10 G.I.M.-Gesellschaft Für Innovative Medizin Gmbh Nfg Ohg Plant components and extracts and uses thereof
EP2212321A4 (en) * 2007-10-22 2011-03-23 Memory Pharm Corp LIGANDS (1,4-DIAZA-BICYCLO [3.2.2] NON-6-EN-4-YL) -HETEROCYCLYL-METHANONE FOR NICOTINIC ACETYLCHOLINE RECEPTORS, USEFUL IN THE TREATMENT OF DISEASE
EP4259619A1 (en) * 2020-12-08 2023-10-18 Disarm Therapeutics, Inc. Benzopyrazole inhibitors of sarm1

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ226000A (en) * 1987-09-10 1991-06-25 Merck Sharp & Dohme Oxadiazolyl-azabicycloheptanes and pharmaceutical compositions
FR2786770B1 (fr) * 1998-12-04 2001-01-19 Synthelabo Derives de 1,4-diazabicyclo[3.2.2.]nonane, leur preparation et leur application en therapeutique
FR2804430B1 (fr) * 2000-01-28 2002-03-22 Sanofi Synthelabo Derives de 4-heteroaryl-1,4-diazabicyclo[3.2.2] nonane, leur preparation et leur application en therapeutique
FR2809730B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo Derives de 1,4-diazabicyclo[3.2.2] nonanebenzoxazole, -benzothiazole et -benzimidazole, leur preparation et leur application therapeutique
US20020086871A1 (en) * 2000-12-29 2002-07-04 O'neill Brian Thomas Pharmaceutical composition for the treatment of CNS and other disorders

Also Published As

Publication number Publication date
FR2845388A1 (fr) 2004-04-09
ATE425980T1 (de) 2009-04-15
DE60326757D1 (de) 2009-04-30
EP1575960A2 (fr) 2005-09-21
FR2845388B1 (fr) 2004-11-12
WO2004033456A3 (fr) 2004-05-27
TWI320413B (en) 2010-02-11
AR041527A1 (es) 2005-05-18
JP4537853B2 (ja) 2010-09-08
WO2004033456A2 (fr) 2004-04-22
AU2003283500A8 (en) 2004-05-04
TW200505926A (en) 2005-02-16
JP2006506356A (ja) 2006-02-23
EP1575960B1 (fr) 2009-03-18

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase