AU2003268687A1 - Novel salt of 2-acylaminothiazole derivative - Google Patents

Novel salt of 2-acylaminothiazole derivative

Info

Publication number
AU2003268687A1
AU2003268687A1 AU2003268687A AU2003268687A AU2003268687A1 AU 2003268687 A1 AU2003268687 A1 AU 2003268687A1 AU 2003268687 A AU2003268687 A AU 2003268687A AU 2003268687 A AU2003268687 A AU 2003268687A AU 2003268687 A1 AU2003268687 A1 AU 2003268687A1
Authority
AU
Australia
Prior art keywords
novel salt
acylaminothiazole derivative
acylaminothiazole
derivative
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003268687A
Inventor
Yuuji Awamura
Fukushi Hirayama
Yuji Koga
Keizo Sugasawa
Ken-Ichi Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of AU2003268687A1 publication Critical patent/AU2003268687A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2003268687A 2002-09-30 2003-09-29 Novel salt of 2-acylaminothiazole derivative Abandoned AU2003268687A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2002-284689 2002-09-30
JP2002284689 2002-09-30
PCT/JP2003/012419 WO2004029049A1 (en) 2002-09-30 2003-09-29 Novel salt of 2-acylaminothiazole derivative

Publications (1)

Publication Number Publication Date
AU2003268687A1 true AU2003268687A1 (en) 2004-04-19

Family

ID=32040589

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003268687A Abandoned AU2003268687A1 (en) 2002-09-30 2003-09-29 Novel salt of 2-acylaminothiazole derivative

Country Status (3)

Country Link
JP (1) JP4317818B2 (en)
AU (1) AU2003268687A1 (en)
WO (1) WO2004029049A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8476249B2 (en) 2009-05-07 2013-07-02 Glaxosmithkline Llc Method of treating thrombocytopenia

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1466912B1 (en) 2002-01-18 2013-04-24 Astellas Pharma Inc. 2-acylaminothiazole derivative or salt thereof
JP4665769B2 (en) * 2005-01-12 2011-04-06 アステラス製薬株式会社 Method for producing acylaminothiazole derivative
US20070203153A1 (en) * 2005-11-08 2007-08-30 Astellas Pharma Inc. Compositions and methods for treating thrombocytopenia
EP2452674B1 (en) * 2006-08-08 2014-03-26 Akarx, Inc. Compositions and methods for increasing blood platelet levels in humans
WO2008073864A1 (en) * 2006-12-12 2008-06-19 Smithkline Beecham Corporation Novel combinations
TWI384986B (en) * 2007-01-17 2013-02-11 Lg Life Sciences Ltd Maleic acid monosalt of antiviral agent and pharmaceutical composition containing the same
UY30915A1 (en) * 2007-02-16 2008-09-02 Smithkline Beecham Corp CANCER TREATMENT METHOD
BRPI0814891A2 (en) 2007-07-31 2015-08-18 Shionogi & Co Pharmaceutical composition containing optically active compound having thrombopoietin receptor agonist activity, and intermediate thereof.
EA024557B1 (en) 2009-05-29 2016-09-30 ГЛЭКСОСМИТКЛАЙН ЭлЭлСи Methods of administration of thrombopoietin agonist compounds
JP2014144916A (en) 2011-08-03 2014-08-14 Astellas Pharma Inc Crystal of 2-acylamino thiazole compound
CN106749226B (en) * 2017-03-15 2019-12-20 广东赛拓医药科技有限公司 Preparation method of avatrombopag maleate crystal form C
CN107383000A (en) * 2017-08-07 2017-11-24 瑞阳制药有限公司 The preparation method of thrombocythemia agent
WO2020044364A1 (en) 2018-08-27 2020-03-05 Mylan Laboratories Limited Polymorphic forms of avatrombopag maleate
CN112480106B (en) * 2020-11-17 2022-09-02 南京海纳医药科技股份有限公司 Preparation method of Alvatripopa maleate impurity
CN112409350B (en) * 2020-11-27 2023-12-19 上海迪赛诺生物医药有限公司 Preparation method of maleic acid atorvastatin crystal form C
CN115057854A (en) * 2022-04-19 2022-09-16 河北常山生化药业股份有限公司 Preparation method of Alvatripopa maleate intermediate
CN115504975A (en) * 2022-10-18 2022-12-23 河北常山凯库得生物技术有限公司 Preparation method of Alvatripopa maleate intermediate
CN116813609A (en) * 2023-07-03 2023-09-29 上海天鹤年药业有限公司 Preparation method of atorvastatin
WO2025132929A2 (en) 2023-12-19 2025-06-26 Synthon B.V Salts of avatrombopag
WO2025133011A1 (en) 2023-12-21 2025-06-26 Synthon B.V Formulation comprising form b of avatrombopag maleate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1357116A4 (en) * 2001-02-02 2005-06-01 Yamanouchi Pharma Co Ltd 2-acylaminothiazole derivative or its salt
EP1466912B1 (en) * 2002-01-18 2013-04-24 Astellas Pharma Inc. 2-acylaminothiazole derivative or salt thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8476249B2 (en) 2009-05-07 2013-07-02 Glaxosmithkline Llc Method of treating thrombocytopenia

Also Published As

Publication number Publication date
WO2004029049A1 (en) 2004-04-08
JPWO2004029049A1 (en) 2006-01-26
JP4317818B2 (en) 2009-08-19

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase