AU2003267411A1 - Bitter taste receptors - Google Patents

Bitter taste receptors

Info

Publication number
AU2003267411A1
AU2003267411A1 AU2003267411A AU2003267411A AU2003267411A1 AU 2003267411 A1 AU2003267411 A1 AU 2003267411A1 AU 2003267411 A AU2003267411 A AU 2003267411A AU 2003267411 A AU2003267411 A AU 2003267411A AU 2003267411 A1 AU2003267411 A1 AU 2003267411A1
Authority
AU
Australia
Prior art keywords
bitter taste
taste receptors
receptors
bitter
taste
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003267411A
Other versions
AU2003267411A8 (en
Inventor
Bernd Bufe
Thomas Hofmann
Dietmar Krautwurst
Christina Kuhn
Wolfgang Meyerhof
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deutsches Institut fuer Ernaehrungsforschung Potsdam Rehbruecke
Original Assignee
Deutsches Institut fuer Ernaehrungsforschung Potsdam Rehbruecke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsches Institut fuer Ernaehrungsforschung Potsdam Rehbruecke filed Critical Deutsches Institut fuer Ernaehrungsforschung Potsdam Rehbruecke
Publication of AU2003267411A8 publication Critical patent/AU2003267411A8/en
Publication of AU2003267411A1 publication Critical patent/AU2003267411A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/86—Addition of bitterness inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
AU2003267411A 2002-09-25 2003-09-25 Bitter taste receptors Abandoned AU2003267411A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41329802P 2002-09-25 2002-09-25
US60/413,298 2002-09-25
PCT/EP2003/010691 WO2004029087A2 (en) 2002-09-25 2003-09-25 Bitter taste receptors

Publications (2)

Publication Number Publication Date
AU2003267411A8 AU2003267411A8 (en) 2004-04-19
AU2003267411A1 true AU2003267411A1 (en) 2004-04-19

Family

ID=32043229

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003267411A Abandoned AU2003267411A1 (en) 2002-09-25 2003-09-25 Bitter taste receptors

Country Status (5)

Country Link
US (3) US7413867B2 (en)
EP (12) EP1543122B1 (en)
AU (1) AU2003267411A1 (en)
DE (1) DE60330159D1 (en)
WO (1) WO2004029087A2 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1292827A4 (en) * 2000-04-07 2006-07-12 Senomyx Inc T2r taste receptors and genes encoding same
US8030008B2 (en) 2001-04-05 2011-10-04 Senomyx, Inc. Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators
US7883856B2 (en) * 2001-04-05 2011-02-08 Senomyx Inc. Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators
EP1523308A4 (en) 2001-07-20 2007-01-10 Us Gov Health & Human Serv Phenylthiocarbamide (ptc) taste receptor
AU2004258071A1 (en) 2003-06-19 2005-01-27 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Variants of human taste receptor genes
US8158372B2 (en) 2004-04-20 2012-04-17 Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke Agonists of a bitter taste receptor and uses thereof
US7829299B2 (en) 2004-11-18 2010-11-09 Deutsches Institut fur Ernahrungforschung Potsdam-Rehbrucke Stiftung des Offentlichen Rechts Agonists of bitter taste receptors and uses thereof
CN101522702A (en) * 2006-09-05 2009-09-02 塞诺米克斯公司 Novel haplotype of human t2r receptor ht2r50 and its use in assays for identifying human bitter taste modulators
EP1975611A1 (en) * 2007-03-29 2008-10-01 Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand Agonists of bitter taste receptors and uses thereof
EP1975612A1 (en) * 2007-03-29 2008-10-01 Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand Agonists of bitter taste receptors and uses thereof
KR20100016044A (en) 2007-03-30 2010-02-12 지보당 에스아 Methods to identify modulators
US8409649B2 (en) 2007-03-30 2013-04-02 Givaudan S.A. Off-note blocking sensory organic compounds
EP1983342A1 (en) 2007-04-18 2008-10-22 Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand Antogonists of bitter taste receptors and uses thereof
CN101960014B (en) * 2008-02-01 2013-10-16 克罗莫塞尔公司 Cell lines and methods for making and using them
NZ594635A (en) * 2009-02-02 2012-12-21 Chromocell Corp Methods for assaying and isolating cell lines which stably expressed a sweet/bitter/umami taste receptor
EP2460010A1 (en) * 2009-07-28 2012-06-06 Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke Agonists and antagonists of human bitter taste receptor tas2r49 and uses thereof
MX346673B (en) 2010-04-15 2017-03-29 Chromocell Corp Compounds, compositions, and methods for reducing or eliminating bitter taste.
US9128079B2 (en) 2011-08-08 2015-09-08 The Coca-Cola Company Methods of using lung or bronchial epithelial cells to identify bitter taste modulators
RU2614776C2 (en) 2011-10-20 2017-03-29 Хромоселл Корпорейшн Compounds, compositions and methods for reducing or eliminating bitter taste
EP2769216B1 (en) 2011-10-20 2017-01-04 Chromocell Corporation Assays for identifying compounds that modulate bitter taste
WO2013072332A1 (en) 2011-11-14 2013-05-23 Givaudan Sa Methods of using antagonists of bitter taste receptors
WO2014111546A1 (en) 2013-01-17 2014-07-24 Universität Wien Method for the identification of bitter tasting compounds and bitter taste modulating compounds
EP2767829A1 (en) 2013-02-18 2014-08-20 Universität Wien A method for identifying bitter principles and bitter-modulating principles
US9169311B2 (en) 2013-03-15 2015-10-27 Applied Food Biotechnology, Inc. Feline bitter taste receptors and methods
ES2797547T3 (en) 2013-03-15 2020-12-02 Applied Food Biotech Inc Feline bitter taste receptors and methods.
RU2015144371A (en) 2013-04-24 2017-05-29 Хромоселл Корпорейшн RESEARCH METHODS FOR IDENTIFICATION OF COMPOUNDS MODULATING Bitter TASTE
US10301275B2 (en) 2017-03-17 2019-05-28 Altria Client Services Llc Sweet taste modulators
WO2023205647A1 (en) * 2022-04-19 2023-10-26 Firmenich Incorporated Reduction of bitter taste of active pharmaceutical ingredients and related assays and screening methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001018050A2 (en) * 1999-09-10 2001-03-15 The Regents Of The University Of California T2r taste receptor family
EP1556401A2 (en) * 1999-11-05 2005-07-27 Human Genome Sciences, Inc. 22 human secreted proteins
EP1292827A4 (en) * 2000-04-07 2006-07-12 Senomyx Inc T2r taste receptors and genes encoding same
WO2002057309A1 (en) * 2001-01-18 2002-07-25 Takeda Chemical Industries, Ltd. Novel g protein-coupled receptor protein and dna thereof
EP1523308A4 (en) * 2001-07-20 2007-01-10 Us Gov Health & Human Serv Phenylthiocarbamide (ptc) taste receptor
US20070059688A1 (en) * 2001-10-12 2007-03-15 Rozengurt Juan E Gastrointestinal chemosensory receptors
AU2004258071A1 (en) * 2003-06-19 2005-01-27 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Variants of human taste receptor genes

Also Published As

Publication number Publication date
EP2272957A2 (en) 2011-01-12
EP2270156A3 (en) 2011-08-10
EP2163623A3 (en) 2010-05-26
EP2267128A3 (en) 2011-08-10
US7955808B2 (en) 2011-06-07
EP2267129B1 (en) 2015-03-25
US20110177085A1 (en) 2011-07-21
EP2270158A2 (en) 2011-01-05
EP2163623A2 (en) 2010-03-17
US20060248602A1 (en) 2006-11-02
EP2270157A2 (en) 2011-01-05
US7413867B2 (en) 2008-08-19
EP2270153A3 (en) 2011-08-10
WO2004029087A2 (en) 2004-04-08
WO2004029087A3 (en) 2004-07-01
AU2003267411A8 (en) 2004-04-19
EP2270154A3 (en) 2011-08-10
EP2270156A2 (en) 2011-01-05
DE60330159D1 (en) 2009-12-31
EP1543122B1 (en) 2009-11-18
EP2270154A2 (en) 2011-01-05
US8709737B2 (en) 2014-04-29
EP2270157A3 (en) 2011-08-03
EP2270155A2 (en) 2011-01-05
EP1543122A2 (en) 2005-06-22
EP2270158A3 (en) 2011-08-03
EP2267128A2 (en) 2010-12-29
EP2267129A2 (en) 2010-12-29
EP2267130A2 (en) 2010-12-29
EP2272957A3 (en) 2011-08-03
EP2267129A3 (en) 2011-08-03
EP2270153A2 (en) 2011-01-05
EP2267130A3 (en) 2011-08-03
US20080287364A1 (en) 2008-11-20
EP2270155A3 (en) 2011-08-10

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase