AU2003263044A1 - Modulators of tnf-alpha and il-1 cell surface receptor activity - Google Patents

Modulators of tnf-alpha and il-1 cell surface receptor activity

Info

Publication number
AU2003263044A1
AU2003263044A1 AU2003263044A AU2003263044A AU2003263044A1 AU 2003263044 A1 AU2003263044 A1 AU 2003263044A1 AU 2003263044 A AU2003263044 A AU 2003263044A AU 2003263044 A AU2003263044 A AU 2003263044A AU 2003263044 A1 AU2003263044 A1 AU 2003263044A1
Authority
AU
Australia
Prior art keywords
tnf
modulators
alpha
cell surface
receptor activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003263044A
Other versions
AU2003263044A8 (en
Inventor
Tatjana Naranda
Lennart Olsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Receptron
Original Assignee
Receptron
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Receptron filed Critical Receptron
Publication of AU2003263044A8 publication Critical patent/AU2003263044A8/en
Publication of AU2003263044A1 publication Critical patent/AU2003263044A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2003263044A 2002-08-29 2003-08-28 Modulators of tnf-alpha and il-1 cell surface receptor activity Abandoned AU2003263044A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40739602P 2002-08-29 2002-08-29
US60/407,396 2002-08-29
PCT/US2003/027381 WO2004020608A2 (en) 2002-08-29 2003-08-28 Modulators of tnf-alpha and il-1 cell surface receptor activity

Publications (2)

Publication Number Publication Date
AU2003263044A8 AU2003263044A8 (en) 2004-03-19
AU2003263044A1 true AU2003263044A1 (en) 2004-03-19

Family

ID=31978475

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003263044A Abandoned AU2003263044A1 (en) 2002-08-29 2003-08-28 Modulators of tnf-alpha and il-1 cell surface receptor activity

Country Status (3)

Country Link
AU (1) AU2003263044A1 (en)
CA (1) CA2496634A1 (en)
WO (1) WO2004020608A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9028822B2 (en) 2002-06-28 2015-05-12 Domantis Limited Antagonists against TNFR1 and methods of use therefor

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6346390B1 (en) * 1996-03-08 2002-02-12 Receptron, Inc. Receptor derived peptides involved in modulation of response to ligand binding

Also Published As

Publication number Publication date
WO2004020608A3 (en) 2005-08-04
CA2496634A1 (en) 2004-03-11
WO2004020608A2 (en) 2004-03-11
AU2003263044A8 (en) 2004-03-19

Similar Documents

Publication Publication Date Title
AU2003234251A1 (en) Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity
EP1558250A4 (en) Gamma-aminoamide modulators of chemokine receptor activity
AU2003230834A1 (en) Antagonists of il-21 and modulation of il-21-mediated t cell responses
AU2003288902A1 (en) Microcapsules and methods of use
EP1558253A4 (en) Piperidinyl-alpha-aminoamide modulators of chemokine receptor activity
AU2003202988A1 (en) Use of modified pyrimidine compounds to promote stem cell migration and proliferation
AU2003217350A1 (en) Proliferated cell lines and uses thereof
AU2003275311A1 (en) Solid micro-perforators and methods of use
AU2003282955A1 (en) Microencapsulation and sustained release of biologically active polypeptides
AU2003218437A1 (en) Alkali-iron-cobalt phosphates and related electrode active materials
AU2003251970A1 (en) Modulators of the glucocorticoid receptor and method
AU2001231154A1 (en) Peptidomimetic modulators of cell adhesion
AU2002326948A1 (en) Piperizinones as modulators of chemokine receptor activity
EP1558599A4 (en) Heteroarylpiperidine modulators of chemokine receptor activity
AU2003259717A1 (en) Modulators of rabggt and methods of use thereof
AU2003221173A1 (en) Placenta-origin mesenchymal cells and medicinal use thereof
AU2001230704A1 (en) Pyrimidine compounds and their use as modulators of chemokine receptor activity
AU2003290432A1 (en) T cell activating gene
AU2003211585A1 (en) Reaction cell and method of using the cell
AU5473800A (en) Cyclopentyl modulators of chemokine receptor activity
AU6895900A (en) Methods of modulating matrix metalloproteinase activity and uses thereof
AU5473400A (en) Cyclopentyl modulators of chemokine receptor activity
AU2003220856A1 (en) Immobilized cells and liposomes and method of immobilizing the same
AU5328500A (en) N-cyclopentyl modulators of chemokine receptor activity
AU2001256555A1 (en) New inhibotor of apoptosis of nerve cells

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase