AU2003251167A1 - Solid dispersion comprising amlodipine, method thereof and pharmaceutical composition comprising the solid dispersion - Google Patents

Solid dispersion comprising amlodipine, method thereof and pharmaceutical composition comprising the solid dispersion

Info

Publication number
AU2003251167A1
AU2003251167A1 AU2003251167A AU2003251167A AU2003251167A1 AU 2003251167 A1 AU2003251167 A1 AU 2003251167A1 AU 2003251167 A AU2003251167 A AU 2003251167A AU 2003251167 A AU2003251167 A AU 2003251167A AU 2003251167 A1 AU2003251167 A1 AU 2003251167A1
Authority
AU
Australia
Prior art keywords
solid dispersion
amlodipine
pharmaceutical composition
dispersion
solid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003251167A
Inventor
Sang Jin Kim
Dong Soo Lee
Kye Kwan Lee
Yun Seok Rhee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Whan In Pharm Co Ltd
Original Assignee
Whan In Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Whan In Pharm Co Ltd filed Critical Whan In Pharm Co Ltd
Publication of AU2003251167A1 publication Critical patent/AU2003251167A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003251167A 2002-07-30 2003-07-29 Solid dispersion comprising amlodipine, method thereof and pharmaceutical composition comprising the solid dispersion Abandoned AU2003251167A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2002-0045020 2002-07-30
KR1020020045020A KR20040011248A (en) 2002-07-30 2002-07-30 Solid dispersion comprising amlodipine, method thereof and pharmaceutical composition comprising the solid dispersion
PCT/KR2003/001512 WO2004010976A1 (en) 2002-07-30 2003-07-29 Solid dispersion comprising amlodipine, method thereof and pharmaceutical composition comprising the solid dispersion

Publications (1)

Publication Number Publication Date
AU2003251167A1 true AU2003251167A1 (en) 2004-02-16

Family

ID=31185766

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003251167A Abandoned AU2003251167A1 (en) 2002-07-30 2003-07-29 Solid dispersion comprising amlodipine, method thereof and pharmaceutical composition comprising the solid dispersion

Country Status (3)

Country Link
KR (1) KR20040011248A (en)
AU (1) AU2003251167A1 (en)
WO (1) WO2004010976A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004075825A2 (en) * 2003-02-28 2004-09-10 Ranbaxy Laboratories Limited Dosage forms of amlodipine and processes for their preparation
KR100604034B1 (en) * 2003-10-08 2006-07-24 주식회사유한양행 A composition of fast dissolving tablets containing amlodipine free base
KR101054143B1 (en) * 2004-04-07 2011-08-03 동아제약주식회사 Fast-acting Solid Dispersion Oral Formulations of Leafy Leaf Extracts and Methods for Making the Same
EP1942872A2 (en) * 2005-11-04 2008-07-16 Eastman Chemical Company Carboxyalkylcellulose esters for administration of poorly soluble pharmaceutically active agents
KR100857724B1 (en) * 2006-06-30 2008-09-10 한올제약주식회사 The solid dispersion of an oral medication for improved the solubility and dissolution rate of poorly water soluble sibutramine
EP4008314A3 (en) * 2007-08-21 2022-11-09 Board of Regents, The University of Texas System Thermo-kinetic mixing for pharmaceutical applications
US8486423B2 (en) * 2007-08-21 2013-07-16 Board Of Regents, The University Of Texas System Thermo-kinetic mixing for pharmaceutical applications
EP2253318B1 (en) * 2008-03-13 2014-08-06 Daiichi Sankyo Company, Limited Improvement of dissolvability of preparation containing olmesartan medoxomil
CN104055740B (en) * 2013-03-18 2016-08-24 青岛大学 A kind of Amlodipine Besylate Tablet oral formulations and preparation method thereof
US10350171B2 (en) 2017-07-06 2019-07-16 Dexcel Ltd. Celecoxib and amlodipine formulation and method of making the same
CN111603449B (en) * 2019-02-22 2022-12-27 鲁南制药集团股份有限公司 Levamlodipine besylate tablet and preparation method thereof
CN113350309B (en) * 2021-08-09 2021-11-12 北京五和博澳药业股份有限公司 Insoluble drug osmotic pump controlled release tablet and preparation method thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3110794B2 (en) * 1991-06-05 2000-11-20 ユーシービージャパン株式会社 Preparation containing 1,4-dihydropyridine derivative
US5340591A (en) * 1992-01-24 1994-08-23 Fujisawa Pharmaceutical Co., Ltd. Method of producing a solid dispersion of the sparingly water-soluble drug, nilvadipine
SI9300504A (en) * 1993-09-28 1995-04-30 Krka Process for preparation solid dispersions and deposits of calcium antagonist dihidropyrimidine derivates and pharmaceutical compositions comprising the same
NZ270439A (en) * 1995-02-02 1996-04-26 Bernard Charles Sherman Solid slow release pharmaceutical composition: carrier is polyethylene glycol and hydrophilic gel-forming polymer
DE19504832A1 (en) * 1995-02-14 1996-08-22 Basf Ag Solid drug preparations
IE80467B1 (en) * 1995-07-03 1998-07-29 Elan Corp Plc Controlled release formulations for poorly soluble drugs

Also Published As

Publication number Publication date
WO2004010976A1 (en) 2004-02-05
KR20040011248A (en) 2004-02-05

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