AU2003248589A1 - Method for determining free thrombin concentration - Google Patents

Method for determining free thrombin concentration

Info

Publication number
AU2003248589A1
AU2003248589A1 AU2003248589A AU2003248589A AU2003248589A1 AU 2003248589 A1 AU2003248589 A1 AU 2003248589A1 AU 2003248589 A AU2003248589 A AU 2003248589A AU 2003248589 A AU2003248589 A AU 2003248589A AU 2003248589 A1 AU2003248589 A1 AU 2003248589A1
Authority
AU
Australia
Prior art keywords
thrombin concentration
determining free
free thrombin
determining
concentration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003248589A
Other languages
English (en)
Inventor
Goran Hansson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of AU2003248589A1 publication Critical patent/AU2003248589A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AU2003248589A 2002-08-16 2003-08-13 Method for determining free thrombin concentration Abandoned AU2003248589A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0202454A SE0202454D0 (sv) 2002-08-16 2002-08-16 Method and apparatus
SE0202454-5 2002-08-16
PCT/SE2003/001273 WO2004016807A1 (en) 2002-08-16 2003-08-13 Method for determining free thrombin concentration

Publications (1)

Publication Number Publication Date
AU2003248589A1 true AU2003248589A1 (en) 2004-03-03

Family

ID=20288745

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003248589A Abandoned AU2003248589A1 (en) 2002-08-16 2003-08-13 Method for determining free thrombin concentration

Country Status (3)

Country Link
AU (1) AU2003248589A1 (sv)
SE (1) SE0202454D0 (sv)
WO (1) WO2004016807A1 (sv)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007073597A1 (en) 2005-12-27 2007-07-05 Mcmaster University Enzyme measurement assay using a modified substrate comprising a substrate attached to a macromolecule via a spacer

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004059055A1 (de) * 2004-12-07 2006-06-08 Dade Behring Marburg Gmbh Verfahren zur automatischen Bestimmung des endogenen Thrombinpotenzials
US9091700B2 (en) 2005-12-27 2015-07-28 Mcmaster University Modified peptide substrate
DE102006035899A1 (de) 2006-07-31 2008-02-07 Dade Behring Marburg Gmbh Polysacharid-Peptid-Konjugate zur Verwendung als Thrombinsubstrate
EP2975383A1 (en) * 2014-07-14 2016-01-20 Johann Wolfgang Goethe-Universität, Frankfurt am Main Method and device for analyzing a fluid medium such as a blood sample
US20200200774A1 (en) 2017-06-20 2020-06-25 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods for identifying whether patients with acute decompensated heart failure (adhf) exhibit a hypercoagulable state

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007073597A1 (en) 2005-12-27 2007-07-05 Mcmaster University Enzyme measurement assay using a modified substrate comprising a substrate attached to a macromolecule via a spacer
EP3660162A1 (en) 2005-12-27 2020-06-03 McMaster University Enzyme measurement assay using a modified substrate comprising a substrate attached to a macromolecule via a spacer

Also Published As

Publication number Publication date
WO2004016807A1 (en) 2004-02-26
SE0202454D0 (sv) 2002-08-16

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase