AU2003242688A1 - Inhibition of nuclear receptors - Google Patents

Inhibition of nuclear receptors

Info

Publication number
AU2003242688A1
AU2003242688A1 AU2003242688A AU2003242688A AU2003242688A1 AU 2003242688 A1 AU2003242688 A1 AU 2003242688A1 AU 2003242688 A AU2003242688 A AU 2003242688A AU 2003242688 A AU2003242688 A AU 2003242688A AU 2003242688 A1 AU2003242688 A1 AU 2003242688A1
Authority
AU
Australia
Prior art keywords
inhibition
nuclear receptors
receptors
nuclear
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003242688A
Inventor
Igor Bendik
Manuel Heim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
Roche Vitamins AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Vitamins AG filed Critical Roche Vitamins AG
Publication of AU2003242688A1 publication Critical patent/AU2003242688A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/111—Antisense spanning the whole gene, or a large part of it
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/53—Physical structure partially self-complementary or closed
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2003242688A 2002-06-20 2003-06-12 Inhibition of nuclear receptors Abandoned AU2003242688A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02013745.1 2002-06-20
EP02013745 2002-06-20
PCT/EP2003/006183 WO2004001045A1 (en) 2002-06-20 2003-06-12 Inhibition of nuclear receptors

Publications (1)

Publication Number Publication Date
AU2003242688A1 true AU2003242688A1 (en) 2004-01-06

Family

ID=29797131

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003242688A Abandoned AU2003242688A1 (en) 2002-06-20 2003-06-12 Inhibition of nuclear receptors

Country Status (2)

Country Link
AU (1) AU2003242688A1 (en)
WO (1) WO2004001045A1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020086356A1 (en) * 2000-03-30 2002-07-04 Whitehead Institute For Biomedical Research RNA sequence-specific mediators of RNA interference
FR2832154B1 (en) * 2001-11-09 2007-03-16 Centre Nat Rech Scient OLIGONUCLEOTIDES INHIBITORS AND THEIR USE FOR SPECIFICALLY REPRESSING A GENE

Also Published As

Publication number Publication date
WO2004001045A1 (en) 2003-12-31

Similar Documents

Publication Publication Date Title
EP1537102A4 (en) Inhibition of phsphoinostide 3-dinase beta
EG23458A (en) Set of elements for assemlying structures
ZA200501913B (en) New compounds for the inhibition of rotamases and use thereof
AU2003202263A1 (en) Roh-kinase inhibitors
HK1077762A1 (en) INHIBITORS OF TFGβ
AU2003219960A1 (en) Child-seat liners
AU2003272069A1 (en) Novel floating dosage form
AU2002326949A1 (en) Method for the inhibition of methanogenesis
IL165475A0 (en) Nitrooxyderivatives of eyclooxygenase-2 inhibitors
EP1567182A4 (en) Preventing desensitization of receptors
AU2003222197A1 (en) Inhibition of rna function
AU2003240668A1 (en) Attenuation of metapneumovirus
AU2003265965A1 (en) Cubicle shield
EP1572950A3 (en) Single domain tdf-related compounds and analogs thereof
GB2423108C (en) Mounting of offshore structures
AU2003283557A1 (en) Shower trap
AU2003299137A1 (en) Inhibition of metallo-beta-lactamase
AU2003210218A1 (en) Opacifiers
AU2003242688A1 (en) Inhibition of nuclear receptors
AU2003248246A1 (en) Hetero-bicyclic compounds
AU2003268812A1 (en) Feeding of toner
AU2003238034A1 (en) Novel use of imidazotriazinones
AU2003217354A1 (en) Synthesis of sulfamidates
AU2003258982A1 (en) Methods of inhibiting pin1-associated states using a fredericamycin a compound
AU2003219424A1 (en) Methods of using alpha 1b-adrenergic receptors

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase