AU2003223923A1 - Peptide nucleic acid conjugates with transporter peptides - Google Patents

Peptide nucleic acid conjugates with transporter peptides

Info

Publication number
AU2003223923A1
AU2003223923A1 AU2003223923A AU2003223923A AU2003223923A1 AU 2003223923 A1 AU2003223923 A1 AU 2003223923A1 AU 2003223923 A AU2003223923 A AU 2003223923A AU 2003223923 A AU2003223923 A AU 2003223923A AU 2003223923 A1 AU2003223923 A1 AU 2003223923A1
Authority
AU
Australia
Prior art keywords
nucleic acid
peptide nucleic
acid conjugates
transporter peptides
transporter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003223923A
Other versions
AU2003223923A8 (en
Inventor
Torben Peter Frandsen
Charlotte Johansen
Soren Kjaerulff
Bjarne Ronfeldt Nielsen
Jakob Tolborg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pantheco AS
Original Assignee
Pantheco AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pantheco AS filed Critical Pantheco AS
Publication of AU2003223923A1 publication Critical patent/AU2003223923A1/en
Publication of AU2003223923A8 publication Critical patent/AU2003223923A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/66—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid the modifying agent being a pre-targeting system involving a peptide or protein for targeting specific cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nanotechnology (AREA)
  • Cell Biology (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003223923A 2002-05-01 2003-05-01 Peptide nucleic acid conjugates with transporter peptides Abandoned AU2003223923A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200200661 2002-05-01
DKPA200200661 2002-05-01
PCT/DK2003/000280 WO2003092736A2 (en) 2002-05-01 2003-05-01 Peptide nucleic acid conjugates with transporter peptides

Publications (2)

Publication Number Publication Date
AU2003223923A1 true AU2003223923A1 (en) 2003-11-17
AU2003223923A8 AU2003223923A8 (en) 2003-11-17

Family

ID=29286046

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003223923A Abandoned AU2003223923A1 (en) 2002-05-01 2003-05-01 Peptide nucleic acid conjugates with transporter peptides

Country Status (2)

Country Link
AU (1) AU2003223923A1 (en)
WO (1) WO2003092736A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8003595B2 (en) 2000-03-01 2011-08-23 Cellectis Amino acid sequences facilitating penetration of a substance of interest into cells and/or cell nuclei
EP1512696A1 (en) * 2003-08-14 2005-03-09 Diatos Amino acid sequences facilitating penetration of a substance of interest into cells and/or cell nuclei
WO2005016960A2 (en) 2003-08-14 2005-02-24 Diatos Amino acid sequences facilitating penetration of a substance of interest into cells and/or cell nuclei
ATE487792T1 (en) * 2003-12-22 2010-11-15 Univ Pennsylvania METHODS AND COMPOSITIONS FOR IDENTIFYING RNA-BINDING PROTEINS
DE102014101663A1 (en) * 2014-02-11 2015-08-13 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Synthetic artificial peptides with antimicrobial activity
WO2016102339A1 (en) * 2014-12-22 2016-06-30 F. Hoffmann-La Roche Ag Cell penetrating peptides
GB2549798A (en) * 2016-04-29 2017-11-01 Univ Bradford Peptides and nanoparticle formulations thereof
CN114605517B (en) * 2022-05-12 2022-09-27 广东海洋大学 Polypeptide LXP-7 with broad-spectrum anticancer effect and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4421079C1 (en) * 1994-06-16 1995-08-17 Peter Dr Rer Nat Seibel New chimaeric peptide nucleic acid construct
BR9809138A (en) * 1997-05-21 2001-08-28 Trustees For The Leland Stanfo Conjugate and method to increase the transport of a selected compound across a biological membrane
US6025140A (en) * 1997-07-24 2000-02-15 Perseptive Biosystems, Inc. Membrane-permeable constructs for transport across a lipid membrane
HUP0203465A2 (en) * 1998-11-11 2003-01-28 Pantheco A/S Conjugates between a peptides and a nucleic acid analog, such as a pna, lna or a morpholino
WO2002079467A2 (en) * 2001-03-29 2002-10-10 Københavns Universitet Antibiotic-free bacterial strain selection with antisense molecules

Also Published As

Publication number Publication date
WO2003092736A3 (en) 2004-06-24
WO2003092736A2 (en) 2003-11-13
AU2003223923A8 (en) 2003-11-17

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase