AU2003219507A1 - Process for the preparation of highly pure torsemide - Google Patents

Process for the preparation of highly pure torsemide

Info

Publication number
AU2003219507A1
AU2003219507A1 AU2003219507A AU2003219507A AU2003219507A1 AU 2003219507 A1 AU2003219507 A1 AU 2003219507A1 AU 2003219507 A AU2003219507 A AU 2003219507A AU 2003219507 A AU2003219507 A AU 2003219507A AU 2003219507 A1 AU2003219507 A1 AU 2003219507A1
Authority
AU
Australia
Prior art keywords
preparation
highly pure
torsemide
pure torsemide
highly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003219507A
Inventor
Marina Etinger
Alexander Glozman
Dmitry Goldring
Arie Gutman
Gennady Nisnevich
Boris Pertsikov
Boris Tishin
Alexander Vilensky
Lev Yudovitch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Finetech Ltd
Original Assignee
Finetech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Finetech Ltd filed Critical Finetech Ltd
Publication of AU2003219507A1 publication Critical patent/AU2003219507A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
AU2003219507A 2002-05-21 2003-04-15 Process for the preparation of highly pure torsemide Abandoned AU2003219507A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL149771 2002-05-21
IL14977102A IL149771A0 (en) 2002-05-21 2002-05-21 Process for preparation of torsemide
PCT/IL2003/000311 WO2003097603A1 (en) 2002-05-21 2003-04-15 Process for the preparation of highly pure torsemide

Publications (1)

Publication Number Publication Date
AU2003219507A1 true AU2003219507A1 (en) 2003-12-02

Family

ID=28460422

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003219507A Abandoned AU2003219507A1 (en) 2002-05-21 2003-04-15 Process for the preparation of highly pure torsemide

Country Status (3)

Country Link
AU (1) AU2003219507A1 (en)
IL (1) IL149771A0 (en)
WO (1) WO2003097603A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115417810A (en) * 2022-09-22 2022-12-02 南京正科医药股份有限公司 Refining method of torasemide crystal form I

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7378527B2 (en) 2004-03-16 2008-05-27 Daqing Che Process for the preparation of torsemide and related intermediates
US9487485B2 (en) 2013-02-28 2016-11-08 Takeda Pharmaceutical Company Limited Method for producing sulfonyl chloride compound
CN110606826B (en) * 2019-05-23 2021-06-01 上海勋和医药科技有限公司 Torasemide sodium monohydrate, crystal forms and compositions thereof
CN114456104B (en) * 2022-01-26 2023-08-25 南京正科医药股份有限公司 Synthesis method of torasemide key intermediate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1477664A (en) * 1974-04-17 1977-06-22 Christiaens Sa A Pyridine derivatives
GB1593609A (en) * 1978-01-31 1981-07-22 Christiaens Sa A Pyridine sulfonamides
WO2001070226A1 (en) * 2000-03-20 2001-09-27 Teva Pharmaceutical Industries Ltd. Novel processes for preparing torsemide intermediate

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115417810A (en) * 2022-09-22 2022-12-02 南京正科医药股份有限公司 Refining method of torasemide crystal form I
CN115417810B (en) * 2022-09-22 2023-10-10 南京正科医药股份有限公司 Refining method of torsemide crystal form I

Also Published As

Publication number Publication date
IL149771A0 (en) 2002-11-10
WO2003097603A1 (en) 2003-11-27

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase