AU2003210422A8 - Recombinase fusion protein with enhanced cellular uptake - Google Patents
Recombinase fusion protein with enhanced cellular uptakeInfo
- Publication number
- AU2003210422A8 AU2003210422A8 AU2003210422A AU2003210422A AU2003210422A8 AU 2003210422 A8 AU2003210422 A8 AU 2003210422A8 AU 2003210422 A AU2003210422 A AU 2003210422A AU 2003210422 A AU2003210422 A AU 2003210422A AU 2003210422 A8 AU2003210422 A8 AU 2003210422A8
- Authority
- AU
- Australia
- Prior art keywords
- fusion protein
- cellular uptake
- enhanced cellular
- recombinase fusion
- recombinase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
- C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02005468A EP1342781A1 (en) | 2002-03-09 | 2002-03-09 | Recombinase fusion protein with enhanced cellular uptake |
EP02005468.0 | 2002-03-09 | ||
US36379702P | 2002-03-13 | 2002-03-13 | |
US60/363,797 | 2002-03-13 | ||
PCT/EP2003/002280 WO2003076561A2 (en) | 2002-03-09 | 2003-03-06 | Recombinase fusion protein with enhanced cellular uptake |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2003210422A1 AU2003210422A1 (en) | 2003-09-22 |
AU2003210422A8 true AU2003210422A8 (en) | 2003-09-22 |
Family
ID=27806514
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2003210422A Abandoned AU2003210422A1 (en) | 2002-03-09 | 2003-03-06 | Recombinase fusion protein with enhanced cellular uptake |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2003210422A1 (en) |
WO (1) | WO2003076561A2 (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005001062A2 (en) * | 2003-06-25 | 2005-01-06 | Gencia Corporation | Modified vectors for organelle transfection |
US20090123468A1 (en) | 2003-10-24 | 2009-05-14 | Gencia Corporation | Transducible polypeptides for modifying metabolism |
US8133733B2 (en) | 2003-10-24 | 2012-03-13 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to target tissues |
US8062891B2 (en) | 2003-10-24 | 2011-11-22 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to plants |
EP1687017B1 (en) | 2003-10-24 | 2013-03-06 | Gencia Corporation | Methods and compositions for delivering polynucleotides |
WO2007132555A1 (en) * | 2006-05-11 | 2007-11-22 | The University Of Tokyo | Cell membrane-permeable peptide and utilization of the same in cell |
CN101678068B (en) | 2007-03-02 | 2015-05-13 | 诺诺公司 | Treating stroke and other diseases without inhibiting n-type calcium channels |
JP5709013B2 (en) | 2009-04-10 | 2015-04-30 | 東亞合成株式会社 | Neuronal differentiation-inducing peptide and use thereof |
JP5858283B2 (en) | 2009-07-29 | 2016-02-10 | 東亞合成株式会社 | Carrier peptide fragment and use thereof |
WO2011013700A1 (en) | 2009-07-29 | 2011-02-03 | 東亞合成株式会社 | Carrier peptide fragment and use thereof |
WO2011052679A1 (en) | 2009-11-02 | 2011-05-05 | 東亞合成株式会社 | Peptide capable of promoting cell proliferation, and use thereof |
WO2011152524A1 (en) | 2010-06-04 | 2011-12-08 | 東亞合成株式会社 | Cell growth-promoting peptide and use thereof |
US9238796B2 (en) | 2010-06-04 | 2016-01-19 | Toagosei Co. Ltd. | Cell growth-promoting peptide and use thereof |
JP6066222B2 (en) | 2012-05-28 | 2017-01-25 | 東亞合成株式会社 | Antibacterial peptides and their use |
US9480727B2 (en) | 2012-10-18 | 2016-11-01 | Toagosei Co. Ltd. | Synthetic peptide for inhibiting expression of type 2 TNF receptor and use thereof |
EP2914731B1 (en) * | 2012-11-01 | 2019-09-11 | California Institute of Technology | Reversible gene expression |
JP6425161B2 (en) * | 2014-04-30 | 2018-11-21 | 国立大学法人名古屋大学 | Projection pathway selective gene expression control |
EP3334756B1 (en) | 2015-08-10 | 2020-06-17 | Cellivery Therapeutics, Inc. | Improved cell-permeable cre (icp-cre) recombinant protein and use thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001086989A (en) * | 1999-09-17 | 2001-04-03 | Univ Osaka | MAMMALIAN Cre RECOMBINASE GENE |
JP2003518947A (en) * | 2000-01-07 | 2003-06-17 | アルテミス・ファーマシューティカルズ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Transduction of recombinase for inducible gene targeting |
-
2003
- 2003-03-06 WO PCT/EP2003/002280 patent/WO2003076561A2/en not_active Application Discontinuation
- 2003-03-06 AU AU2003210422A patent/AU2003210422A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2003076561A3 (en) | 2004-01-22 |
AU2003210422A1 (en) | 2003-09-22 |
WO2003076561A2 (en) | 2003-09-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |