AU2003205088A1 - Modulation of cop9 signalsome isopeptidase activity - Google Patents

Modulation of cop9 signalsome isopeptidase activity

Info

Publication number
AU2003205088A1
AU2003205088A1 AU2003205088A AU2003205088A AU2003205088A1 AU 2003205088 A1 AU2003205088 A1 AU 2003205088A1 AU 2003205088 A AU2003205088 A AU 2003205088A AU 2003205088 A AU2003205088 A AU 2003205088A AU 2003205088 A1 AU2003205088 A1 AU 2003205088A1
Authority
AU
Australia
Prior art keywords
modulation
isopeptidase activity
signalsome
cop9
cop9 signalsome
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003205088A
Other versions
AU2003205088A8 (en
Inventor
Xavier I. Ambroggio
Gregory Cope
Raymond J. Deshaies
Rati Verma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
California Institute of Technology CalTech
Original Assignee
California Institute of Technology CalTech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/046,961 external-priority patent/US6846663B2/en
Application filed by California Institute of Technology CalTech filed Critical California Institute of Technology CalTech
Publication of AU2003205088A1 publication Critical patent/AU2003205088A1/en
Publication of AU2003205088A8 publication Critical patent/AU2003205088A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
AU2003205088A 2002-01-14 2003-01-09 Modulation of cop9 signalsome isopeptidase activity Abandoned AU2003205088A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US10/047,253 2002-01-14
US10/046,961 2002-01-14
US10/046,961 US6846663B2 (en) 2001-01-12 2002-01-14 Regulation of target protein activity through modifier proteins
US10/047,253 US7291494B2 (en) 2001-01-12 2002-01-14 Regulation of target protein activity through modifier proteins
US35533402P 2002-02-06 2002-02-06
US60/355,334 2002-02-06
PCT/US2003/000767 WO2003060476A2 (en) 2002-01-14 2003-01-09 Modulation of cop9 signalsome isopeptidase activity

Publications (2)

Publication Number Publication Date
AU2003205088A1 true AU2003205088A1 (en) 2003-07-30
AU2003205088A8 AU2003205088A8 (en) 2003-07-30

Family

ID=27367027

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003205088A Abandoned AU2003205088A1 (en) 2002-01-14 2003-01-09 Modulation of cop9 signalsome isopeptidase activity

Country Status (2)

Country Link
AU (1) AU2003205088A1 (en)
WO (1) WO2003060476A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7479555B2 (en) 1999-07-21 2009-01-20 Ceres, Inc. Polynucleotides having a nucleotide sequence that encodes a polypeptide having MOV34 family activity
WO2006128196A2 (en) 2005-05-27 2006-11-30 Proteolix, Inc. Novel substrate for rpn 11 enzymatic activity

Also Published As

Publication number Publication date
AU2003205088A8 (en) 2003-07-30
WO2003060476A2 (en) 2003-07-24
WO2003060476A3 (en) 2004-07-29

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase