AU2002365025A1 - Streptogramin derivatives, preparation thereof and compositions containing same - Google Patents

Streptogramin derivatives, preparation thereof and compositions containing same

Info

Publication number
AU2002365025A1
AU2002365025A1 AU2002365025A AU2002365025A AU2002365025A1 AU 2002365025 A1 AU2002365025 A1 AU 2002365025A1 AU 2002365025 A AU2002365025 A AU 2002365025A AU 2002365025 A AU2002365025 A AU 2002365025A AU 2002365025 A1 AU2002365025 A1 AU 2002365025A1
Authority
AU
Australia
Prior art keywords
streptogramin
derivatives
preparation
compositions containing
containing same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002365025A
Inventor
Eric Bacque
Jean-Claude Barriere
Gerard Puchault
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of AU2002365025A1 publication Critical patent/AU2002365025A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

Streptogramin A derivatives (I) are new. Streptogramin A derivatives of formula (I) and their salts are new: R1 = halo, OH, 1-6C alkoxy, N3, SCN or NR'R''; R' = H or Me; R'' = A, OA or NA'A''; A = H, 1-6C alkyl, cycloalkyl, allyl, propynyl or benzyl; A', A'' = Me; or NA'A'' = a 4- or 5-membered ring optionally containing another heteroatom selected from N, O or S; R'1 = H; R2 = halo, 1-6C alkyl, 2-6C alkenyl, 2-6C alkynyl, phenyl, heteroaryl, 1-6C alkylthio, phenylthio or heteroarylthio; R3 = H, Me or Et; and R1+R'1 = oxo. Independent claims are also included for: (1) a process for preparing compounds (I); (2) polyanions derived from selected compounds (I; R2= H) (15 formulas given); (3) a pharmaceutical composition comprising a compound (I) and optionally at least one streptogramin B derivative and/or one or more diluents or adjuvants.
AU2002365025A 2001-12-26 2002-12-23 Streptogramin derivatives, preparation thereof and compositions containing same Abandoned AU2002365025A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR01/16856 2001-12-26
FR0116856A FR2833954B1 (en) 2001-12-26 2001-12-26 STREPTOGRAMIN DERIVATIVES, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM
PCT/FR2002/004529 WO2003055891A1 (en) 2001-12-26 2002-12-23 Streptogramin derivatives, preparation thereof and compositions containing same

Publications (1)

Publication Number Publication Date
AU2002365025A1 true AU2002365025A1 (en) 2003-07-15

Family

ID=8870982

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002365025A Abandoned AU2002365025A1 (en) 2001-12-26 2002-12-23 Streptogramin derivatives, preparation thereof and compositions containing same

Country Status (14)

Country Link
EP (1) EP1461342B1 (en)
JP (1) JP4443928B2 (en)
AT (1) ATE356133T1 (en)
AU (1) AU2002365025A1 (en)
CA (1) CA2470447C (en)
CY (1) CY1106642T1 (en)
DE (1) DE60218740T2 (en)
DK (1) DK1461342T3 (en)
ES (1) ES2283654T3 (en)
FR (1) FR2833954B1 (en)
MX (1) MXPA04005536A (en)
PT (1) PT1461342E (en)
SI (1) SI1461342T1 (en)
WO (1) WO2003055891A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070117769A1 (en) * 2003-09-29 2007-05-24 Maines Mahin D Methods of modulating cell cycle and cell signaling pathways using biliverdin reductase

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2206879A (en) * 1987-07-07 1989-01-18 May & Baker Ltd Novel pristinamycin IIB derivatives, their preparation and pharmaceutical compositions containing them
US5242938A (en) * 1992-08-27 1993-09-07 Merck & Co., Inc. Derivatives of virginiamycin M1

Also Published As

Publication number Publication date
DK1461342T3 (en) 2007-07-02
DE60218740T2 (en) 2007-11-22
PT1461342E (en) 2007-06-11
WO2003055891A1 (en) 2003-07-10
CY1106642T1 (en) 2012-01-25
EP1461342A1 (en) 2004-09-29
FR2833954B1 (en) 2004-03-12
ES2283654T3 (en) 2007-11-01
JP2005519050A (en) 2005-06-30
SI1461342T1 (en) 2007-08-31
ATE356133T1 (en) 2007-03-15
EP1461342B1 (en) 2007-03-07
CA2470447A1 (en) 2003-07-10
JP4443928B2 (en) 2010-03-31
MXPA04005536A (en) 2004-09-10
DE60218740D1 (en) 2007-04-19
CA2470447C (en) 2011-11-29
FR2833954A1 (en) 2003-06-27

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase