AU2002364250A1 - Detection of molecular interactions by beta-lactamase reporter fragment complementation - Google Patents

Detection of molecular interactions by beta-lactamase reporter fragment complementation

Info

Publication number
AU2002364250A1
AU2002364250A1 AU2002364250A AU2002364250A AU2002364250A1 AU 2002364250 A1 AU2002364250 A1 AU 2002364250A1 AU 2002364250 A AU2002364250 A AU 2002364250A AU 2002364250 A AU2002364250 A AU 2002364250A AU 2002364250 A1 AU2002364250 A1 AU 2002364250A1
Authority
AU
Australia
Prior art keywords
beta
detection
molecular interactions
fragment complementation
lactamase reporter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002364250A
Other versions
AU2002364250A8 (en
Inventor
Robert F. Balint
Helen M. Blau
Jeng-Horng Her
Thomas S. Wehrman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Publication of AU2002364250A8 publication Critical patent/AU2002364250A8/en
Publication of AU2002364250A1 publication Critical patent/AU2002364250A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • G01N2333/986—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides (3.5.2), e.g. beta-lactamase (penicillinase, 3.5.2.6), creatinine amidohydrolase (creatininase, EC 3.5.2.10), N-methylhydantoinase (3.5.2.6)

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2002364250A 2001-12-26 2002-12-26 Detection of molecular interactions by beta-lactamase reporter fragment complementation Abandoned AU2002364250A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34475701P 2001-12-26 2001-12-26
US60/344,757 2001-12-26
PCT/US2002/041587 WO2003058197A2 (en) 2001-12-26 2002-12-26 Detection of molecular interactions by beta-lactamase reporter fragment complementation

Publications (2)

Publication Number Publication Date
AU2002364250A8 AU2002364250A8 (en) 2003-07-24
AU2002364250A1 true AU2002364250A1 (en) 2003-07-24

Family

ID=23351896

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002364250A Abandoned AU2002364250A1 (en) 2001-12-26 2002-12-26 Detection of molecular interactions by beta-lactamase reporter fragment complementation

Country Status (2)

Country Link
AU (1) AU2002364250A1 (en)
WO (1) WO2003058197A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8148110B2 (en) 1999-03-15 2012-04-03 The Board Of Trustees Of The Leland Stanford Junior University Detection of molecular interactions by β-lactamase reporter fragment complementation
WO2005113838A2 (en) * 2004-05-18 2005-12-01 The Board Of Trustees Of The Leland Stanford Junior University Detection of protein translocation by beta-galactosidase reporter fragment complementation
EP1847604A1 (en) * 2006-04-19 2007-10-24 Millegen Intracellular method for selecting a peptide or polypeptide which binds to a bait peptide or polypeptide
US8426138B2 (en) 2006-12-26 2013-04-23 The Board Of Trustees Of The Leland Stanford Junior University Detection of sub-cellular compartment localization of a molecule using a reduced affinity enzyme complementation reporter system
US8101373B2 (en) 2007-10-12 2012-01-24 Discoverx Corporation β-galactosidase donor fragments

Also Published As

Publication number Publication date
WO2003058197A2 (en) 2003-07-17
AU2002364250A8 (en) 2003-07-24
WO2003058197A3 (en) 2004-01-22

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase