AU2002361390A8 - Anti-cd7 immunotoxin as fusion protein - Google Patents

Anti-cd7 immunotoxin as fusion protein

Info

Publication number
AU2002361390A8
AU2002361390A8 AU2002361390A AU2002361390A AU2002361390A8 AU 2002361390 A8 AU2002361390 A8 AU 2002361390A8 AU 2002361390 A AU2002361390 A AU 2002361390A AU 2002361390 A AU2002361390 A AU 2002361390A AU 2002361390 A8 AU2002361390 A8 AU 2002361390A8
Authority
AU
Australia
Prior art keywords
immunotoxin
fusion protein
fusion
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002361390A
Other versions
AU2002361390A1 (en
Inventor
Matthias Peipp
Georg Heinrich Maximilian Fey
Martin Gramatzki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Friedrich Alexander Univeritaet Erlangen Nuernberg FAU
Original Assignee
Friedrich Alexander Univeritaet Erlangen Nuernberg FAU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Friedrich Alexander Univeritaet Erlangen Nuernberg FAU filed Critical Friedrich Alexander Univeritaet Erlangen Nuernberg FAU
Publication of AU2002361390A1 publication Critical patent/AU2002361390A1/en
Publication of AU2002361390A8 publication Critical patent/AU2002361390A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU2002361390A 2001-12-14 2002-12-11 Anti-cd7 immunotoxin as fusion protein Abandoned AU2002361390A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33942201P 2001-12-14 2001-12-14
US60/339,422 2001-12-14
PCT/EP2002/014064 WO2003051926A2 (en) 2001-12-14 2002-12-11 Anti-cd7 immunotoxin as fusion protein

Publications (2)

Publication Number Publication Date
AU2002361390A1 AU2002361390A1 (en) 2003-06-30
AU2002361390A8 true AU2002361390A8 (en) 2003-06-30

Family

ID=23328933

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002361390A Abandoned AU2002361390A1 (en) 2001-12-14 2002-12-11 Anti-cd7 immunotoxin as fusion protein

Country Status (2)

Country Link
AU (1) AU2002361390A1 (en)
WO (1) WO2003051926A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1748050A1 (en) * 2005-07-28 2007-01-31 Rijksuniversiteit Groningen Targeting-enhanced activation of galectins
US20070178103A1 (en) * 2006-01-30 2007-08-02 Fey Georg H CD19-specific immunotoxin and treatment method
WO2007122511A2 (en) * 2006-04-21 2007-11-01 Mab-Factory Gmbh Antibody-rnase-conjugate
CA2705289A1 (en) * 2007-11-13 2009-05-22 The Scripps Research Institute Production of cytotoxic antibody-toxin fusion in eukaryotic algae
EP3797847A1 (en) 2010-07-30 2021-03-31 Medlmmune, LLC Purified active polypeptides or immunoconjugates
CN102154355A (en) * 2011-01-06 2011-08-17 武汉大学 Recombinant immunotoxin CCL25-PE38 gene and preparation method as well as application thereof
CN102161998B (en) * 2011-01-14 2013-01-09 中国人民解放军军事医学科学院附属医院 Deoxyribonucleic acid (DNA) vaccine based on B7-1-PE40KDEL exotoxin fusion gene and application thereof
KR101521224B1 (en) * 2012-12-20 2015-05-19 한양대학교 산학협력단 Humanized single chain fragment antibody(scFv) carrier specific for T cell
CA2975851A1 (en) 2015-02-06 2016-08-11 National University Of Singapore Methods for enhancing efficacy of therapeutic immune cells
WO2017213979A1 (en) * 2016-06-06 2017-12-14 St. Jude Children's Research Hospital Anti-cd7 chimeric antigen receptor and method of use thereof
US20200000937A1 (en) * 2016-08-03 2020-01-02 Washington University Gene editing of car-t cells for the treatment of t cell malignancies with chimeric antigen receptors
KR20240099512A (en) * 2016-11-22 2024-06-28 싱가포르국립대학교 Blockade of cd7 expression and chimeric antigen receptors for immunotherapy of t-cell malignancies
EP3634498A4 (en) * 2017-06-09 2021-08-25 Rhode Island Council on Postsecondary Education Linked and other ph-triggered compounds
CN111247241A (en) 2017-08-10 2020-06-05 新加坡国立大学 T cell receptor-deficient chimeric antigen receptor T cells and methods of use thereof
EP3802798A4 (en) * 2018-05-31 2022-05-11 Washington University Chimeric antigen receptor t cells (car-t) for the treatment of cancer
WO2023155852A1 (en) * 2022-02-17 2023-08-24 上海优替济生生物医药有限公司 Modified immune effector cells and uses thereof
CN114560943B (en) * 2022-02-28 2022-12-16 先进生物(苏州)有限公司 CD7-CAR-T cell and preparation method and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6372217B1 (en) * 1997-06-03 2002-04-16 Regents Of The University Of Minnesota Methods for the treatment of CD7+ viral infection with TXU-7-PAP
EP1287147B1 (en) * 2000-05-18 2009-12-16 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE DEPARTMENT OF HEALTH & HUMAN SERVICES Immunotoxin fusion proteins and means for expression thereof

Also Published As

Publication number Publication date
WO2003051926A3 (en) 2003-09-04
WO2003051926A2 (en) 2003-06-26
AU2002361390A1 (en) 2003-06-30

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase