AU2002360409A1 - Methods and intermediates for the synthesis of azepines - Google Patents

Methods and intermediates for the synthesis of azepines

Info

Publication number
AU2002360409A1
AU2002360409A1 AU2002360409A AU2002360409A AU2002360409A1 AU 2002360409 A1 AU2002360409 A1 AU 2002360409A1 AU 2002360409 A AU2002360409 A AU 2002360409A AU 2002360409 A AU2002360409 A AU 2002360409A AU 2002360409 A1 AU2002360409 A1 AU 2002360409A1
Authority
AU
Australia
Prior art keywords
azepines
intermediates
synthesis
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002360409A
Other versions
AU2002360409A8 (en
Inventor
Jose J. Conde
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of AU2002360409A1 publication Critical patent/AU2002360409A1/en
Publication of AU2002360409A8 publication Critical patent/AU2002360409A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C223/00—Compounds containing amino and —CHO groups bound to the same carbon skeleton
    • C07C223/02—Compounds containing amino and —CHO groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU2002360409A 2001-11-21 2002-11-20 Methods and intermediates for the synthesis of azepines Abandoned AU2002360409A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33194901P 2001-11-21 2001-11-21
US60/331,949 2001-11-21
PCT/US2002/037423 WO2003045909A2 (en) 2001-11-21 2002-11-20 Methods and intermediates for the synthesis of azepines

Publications (2)

Publication Number Publication Date
AU2002360409A1 true AU2002360409A1 (en) 2003-06-10
AU2002360409A8 AU2002360409A8 (en) 2003-06-10

Family

ID=23296044

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002360409A Abandoned AU2002360409A1 (en) 2001-11-21 2002-11-20 Methods and intermediates for the synthesis of azepines

Country Status (2)

Country Link
AU (1) AU2002360409A1 (en)
WO (1) WO2003045909A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7071184B2 (en) 2000-03-21 2006-07-04 Smithkline Beecham Corporation Protease inhibitors
JP2007520491A (en) * 2004-01-23 2007-07-26 スミスクライン・ビーチャム・コーポレイション Benzofuran-2-carboxylic acid {(S) -3-methyl-1-[(4S, 7R) -7-methyl-3-oxo-1- (pyridin-2-sulfonyl) -azepan-4-ylcarbamoyl]- Butyl} -amide production method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7071184B2 (en) * 2000-03-21 2006-07-04 Smithkline Beecham Corporation Protease inhibitors

Also Published As

Publication number Publication date
WO2003045909A3 (en) 2003-12-11
AU2002360409A8 (en) 2003-06-10
WO2003045909A2 (en) 2003-06-05

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase