AU2002338666A1 - Multiplication of viruses in a cell culture - Google Patents

Multiplication of viruses in a cell culture

Info

Publication number
AU2002338666A1
AU2002338666A1 AU2002338666A AU2002338666A AU2002338666A1 AU 2002338666 A1 AU2002338666 A1 AU 2002338666A1 AU 2002338666 A AU2002338666 A AU 2002338666A AU 2002338666 A AU2002338666 A AU 2002338666A AU 2002338666 A1 AU2002338666 A1 AU 2002338666A1
Authority
AU
Australia
Prior art keywords
viruses
multiplication
cell culture
culture
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2002338666A
Other versions
AU2002338666B2 (en
Inventor
Christian Frech
Jens-Peter Gregersen
Holger Lubben
Jurgen Vorlop
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GSK Vaccines GmbH
Original Assignee
Novartis Vaccines and Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10144903A external-priority patent/DE10144903A1/en
Application filed by Novartis Vaccines and Diagnostics GmbH filed Critical Novartis Vaccines and Diagnostics GmbH
Publication of AU2002338666A1 publication Critical patent/AU2002338666A1/en
Application granted granted Critical
Publication of AU2002338666B2 publication Critical patent/AU2002338666B2/en
Assigned to Noartis Vaccines and Diagnostics GmbH & Co. KG reassignment Noartis Vaccines and Diagnostics GmbH & Co. KG Alteration of Name(s) in Register under S187 Assignors: CHIRON BEHRING GMBH & CO.
Assigned to NOVARTIS VACCINES AND DIAGNOSTICS GMBH reassignment NOVARTIS VACCINES AND DIAGNOSTICS GMBH Request to Amend Deed and Register Assignors: NOVARTIS VACCINES AND DIAGNOSTICS GMBH & CO. KG
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

AU2002338666A 2001-09-12 2002-09-11 Multiplication of viruses in a cell culture Ceased AU2002338666B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10144903.8 2001-09-12
DE10144903A DE10144903A1 (en) 2001-09-12 2001-09-12 Replication of virus in cell cultures, useful for preparing vaccines and diagnostic reagents, where replication of cells and virus is simultaneous
PCT/EP2002/010207 WO2003023025A1 (en) 2001-09-12 2002-09-11 Multiplication of viruses in a cell culture

Publications (2)

Publication Number Publication Date
AU2002338666A1 true AU2002338666A1 (en) 2003-06-19
AU2002338666B2 AU2002338666B2 (en) 2008-11-20

Family

ID=7698761

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002338666A Ceased AU2002338666B2 (en) 2001-09-12 2002-09-11 Multiplication of viruses in a cell culture

Country Status (17)

Country Link
US (1) US20050118698A1 (en)
EP (1) EP1427817B1 (en)
JP (2) JP2005502357A (en)
KR (1) KR100968141B1 (en)
AT (1) ATE466932T1 (en)
AU (1) AU2002338666B2 (en)
BR (1) BR0212469A (en)
CA (1) CA2456561A1 (en)
CY (1) CY1110716T1 (en)
DE (2) DE10144903A1 (en)
DK (1) DK1427817T3 (en)
ES (1) ES2345606T3 (en)
HK (1) HK1062029A1 (en)
NZ (1) NZ532203A (en)
PT (1) PT1427817E (en)
SI (1) SI1427817T1 (en)
WO (1) WO2003023025A1 (en)

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CN101094915A (en) * 2004-05-20 2007-12-26 益得生物医学公司 Process for the production of an influenza vaccine
DE602005024827D1 (en) 2004-09-09 2010-12-30 Novartis Vaccines & Diagnostic REDUCTION OF POTENTIAL IATROGENIC RISKS ASSOCIATED WITH INFLUENZA VACCINES
NZ567817A (en) 2005-11-01 2012-01-12 Novartis Vaccines & Diagnostic Cell-derived viral vaccines with low levels of residual cell DNA by beta-propiolactone treatment
US20110180430A1 (en) 2005-11-04 2011-07-28 Novartis Vaccines And Diagnostics Srl Adjuvanted influenza vaccines including cytokine-inducing agents
CA2628152C (en) 2005-11-04 2016-02-02 Novartis Vaccines And Diagnostics S.R.L. Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture
EA014028B1 (en) 2005-11-04 2010-08-30 Новартис Вэксинс Энд Диагностикс Срл Emulsions with free aqueous-phase surfactant as adjuvants for split influenza vaccines
NZ568211A (en) 2005-11-04 2011-11-25 Novartis Vaccines & Diagnostic Influenza vaccines including combinations of particulate adjuvants and immunopotentiators
WO2007052155A2 (en) 2005-11-04 2007-05-10 Novartis Vaccines And Diagnostics Srl Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant
EP2004226A1 (en) 2006-03-24 2008-12-24 Novartis Vaccines and Diagnostics GmbH & Co. KG Storage of influenza vaccines without refrigeration
GB0614460D0 (en) 2006-07-20 2006-08-30 Novartis Ag Vaccines
CA2663196A1 (en) * 2006-09-11 2008-03-20 Novartis Ag Making influenza virus vaccines without using eggs
WO2008105931A2 (en) 2006-09-15 2008-09-04 Medimmune Vaccines, Inc. Mdck cell lines supporting viral growth to high titers and bioreactor process using the same
EA201070066A1 (en) 2007-06-27 2010-06-30 Новартис Аг VACCINES AGAINST FLU WITH LOW CONTENT OF ADDITIVES
GB0810305D0 (en) 2008-06-05 2008-07-09 Novartis Ag Influenza vaccination
CN102215865B (en) 2008-09-24 2013-10-30 米迪缪尼有限公司 Methods for purification of viruses
CN102216450B (en) 2008-09-24 2014-05-14 米迪缪尼有限公司 Methods for cultivating cells, propagating and purifying viruses
US20110217330A1 (en) 2008-11-05 2011-09-08 Bruno Rene Andre Novel method
DE102010018462A1 (en) 2009-04-27 2011-04-07 Novartis Ag Vaccines for protection against influenza
AU2010309404B2 (en) * 2009-10-20 2015-07-09 Seqirus UK Limited Improved reverse genetics methods for virus rescue
JP2013523175A (en) 2010-04-14 2013-06-17 イーエムディー・ミリポア・コーポレーション Method for producing high-titer and high-purity virus stock and method for using the same
BR112012028146A2 (en) 2010-05-06 2015-09-15 Novartis Ag organic peroxide compounds for inactivation of microorganisms
EP2571520B1 (en) 2010-05-21 2018-04-04 Seqirus UK Limited Influenza virus reassortment method
PL2575872T3 (en) 2010-06-01 2021-02-22 Seqirus UK Limited Concentration of influenza vaccine antigens without lyophilization
JP5976639B2 (en) 2010-06-01 2016-08-23 ノバルティス アーゲー Concentration and lyophilization of influenza vaccine antigens
AU2011290471B2 (en) 2010-08-20 2015-08-20 Novartis Ag Soluble needle arrays for delivery of influenza vaccines
DK2675476T3 (en) * 2011-02-17 2015-12-14 Boehringer Ingelheim Vetmed Process for producing PRRSV on a commercial scale
CA2829774C (en) 2011-03-14 2019-09-24 National Research Council Of Canada Method of viral production in cells
GB201216121D0 (en) 2012-09-10 2012-10-24 Novartis Ag Sample quantification by disc centrifugation
CA2866465A1 (en) 2012-03-06 2013-09-12 Crucell Holland B.V. Improved vaccination against influenza
US20150210986A1 (en) * 2012-08-24 2015-07-30 Ge Healthcare Bio-Sciences Corp. Virus purification and formulation process
KR101370512B1 (en) 2013-06-07 2014-03-06 재단법인 목암생명공학연구소 Mdck-derived cell lines suspension-cultured in a protein-free medium and method for propagating virus using the same
US11013795B2 (en) 2015-06-26 2021-05-25 Seqirus UK Limited Antigenically matched influenza vaccines
HUE051783T2 (en) 2015-07-07 2021-03-29 Seqirus Uk Ltd Method for quantifying immunogenic hemagglutinin
CN105561317B (en) * 2015-12-22 2018-03-20 肇庆大华农生物药品有限公司 Recombinant pseudorabies virus vaccine heat-resisting lyophilized protecting agent and preparation method thereof
CN108239619A (en) * 2016-12-23 2018-07-03 甘肃健顺生物科技有限公司 The second order culture process technology of suspension mdck cell related vaccines production
CN108570444A (en) * 2017-11-09 2018-09-25 甘肃健顺生物科技有限公司 ST cells tame suspension process and second order virus production technique
CN108570445A (en) * 2017-11-09 2018-09-25 甘肃健顺生物科技有限公司 PK15 cells tame suspension process and second order virus production technique
CN108570454A (en) * 2017-11-09 2018-09-25 甘肃健顺生物科技有限公司 MDBK tames suspension process and second order virus production technique
IL293031A (en) 2019-11-18 2022-07-01 Seqirus Pty Ltd Method for producing reassortant influenza viruses
KR102444684B1 (en) * 2020-04-29 2022-09-16 에스케이바이오사이언스(주) Method for producing influenza virus using single-use cultivation process system

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19612966B4 (en) * 1996-04-01 2009-12-10 Novartis Vaccines And Diagnostics Gmbh & Co. Kg MDCK cells and methods of propagating influenza viruses
US6110724A (en) * 1996-10-18 2000-08-29 The Research Foundation For Microbial Diseases Of Osaka University Rotavirus antigen, vaccine and diagnostic agent for rotavirus infections, and a method for producing the antigen
GB9915413D0 (en) * 1999-07-01 1999-09-01 Glaxo Group Ltd Propagation method
DE60142506D1 (en) * 2000-03-03 2010-08-19 Chemo Sero Therapeut Res Inst CELL USED IN SERUM FREE CULTURE, CULTURAL SUSPENSION AND PROCEDURE FOR VIRUS PRODUCTION AS A VACCINATE USING THE CELL

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