AU2002333378A1 - Isoprenyl derivatives and their use in the treatment and prevention of osteoporosis and cardiovascular calcification - Google Patents

Isoprenyl derivatives and their use in the treatment and prevention of osteoporosis and cardiovascular calcification

Info

Publication number
AU2002333378A1
AU2002333378A1 AU2002333378A AU2002333378A AU2002333378A1 AU 2002333378 A1 AU2002333378 A1 AU 2002333378A1 AU 2002333378 A AU2002333378 A AU 2002333378A AU 2002333378 A AU2002333378 A AU 2002333378A AU 2002333378 A1 AU2002333378 A1 AU 2002333378A1
Authority
AU
Australia
Prior art keywords
osteoporosis
prevention
treatment
cardiovascular calcification
isoprenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002333378A
Inventor
Ceer Vermeer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VITAK BV
Original Assignee
VITAK BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by VITAK BV filed Critical VITAK BV
Publication of AU2002333378A1 publication Critical patent/AU2002333378A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/02—Quinones with monocyclic quinoid structure
    • C07C50/06—Quinones with monocyclic quinoid structure with unsaturation outside the quinoid structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/10—Quinones the quinoid structure being part of a condensed ring system containing two rings
    • C07C50/14—Quinones the quinoid structure being part of a condensed ring system containing two rings with unsaturation outside the ring system, e.g. vitamin K1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C07C69/616—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/78—Benzoic acid esters
AU2002333378A 2001-08-03 2002-08-05 Isoprenyl derivatives and their use in the treatment and prevention of osteoporosis and cardiovascular calcification Abandoned AU2002333378A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01202955.9 2001-08-03
EP01202955 2001-08-03
PCT/EP2002/008917 WO2003013420A2 (en) 2001-08-03 2002-08-05 Isoprenyl derivatives and their use in the treatment and prevention of osteoporosis and cardiovascular calcification

Publications (1)

Publication Number Publication Date
AU2002333378A1 true AU2002333378A1 (en) 2003-02-24

Family

ID=8180752

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002333378A Abandoned AU2002333378A1 (en) 2001-08-03 2002-08-05 Isoprenyl derivatives and their use in the treatment and prevention of osteoporosis and cardiovascular calcification

Country Status (3)

Country Link
EP (1) EP1414387A2 (en)
AU (1) AU2002333378A1 (en)
WO (1) WO2003013420A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60128179T2 (en) 2000-05-12 2008-01-10 Nattopharma Asa Foods containing vitamin K2
GB0220182D0 (en) 2002-08-30 2002-10-09 Cardiovascular Res Inst Maastr Organic compounds
US20050158329A1 (en) 2004-01-21 2005-07-21 Ghosh Swapan K. Novel phytol derived immunoadjuvants and their use in vaccine formulations
ES2363368T5 (en) † 2005-06-03 2015-03-02 Nattopharma Asa Use of vitamin K to reverse the calcification of blood vessels
GB2476644B (en) 2009-12-23 2012-11-14 Haomamedica Ltd 1,4-Dihydro-1,4-dioxonaphtalene derivatives for the treatment of osteoporosis
KR20140039141A (en) * 2010-12-17 2014-04-01 비택 비.브이. Use of vitamin k for weight maintenance and weight control

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL78611A0 (en) * 1986-04-23 1986-08-31 Yeda Res & Dev Production of polyprenoid and ubiquinone-type compounds
EP0636598B1 (en) * 1993-07-26 1997-04-09 Eisai Chemical Co., Ltd. Preparation process of naphthoquinone derivatives and intermediates for the preparation thereof
GB9713620D0 (en) * 1997-06-28 1997-09-03 Boots Co Plc Composition
DE60128179T2 (en) * 2000-05-12 2008-01-10 Nattopharma Asa Foods containing vitamin K2

Also Published As

Publication number Publication date
WO2003013420A3 (en) 2003-11-06
WO2003013420A2 (en) 2003-02-20
EP1414387A2 (en) 2004-05-06

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase