AU2002329459A1 - 8-azabicyclo(3.2.1)octane ether derivatives and their use as neurokinin receptor antagonists - Google Patents

8-azabicyclo(3.2.1)octane ether derivatives and their use as neurokinin receptor antagonists

Info

Publication number
AU2002329459A1
AU2002329459A1 AU2002329459A AU2002329459A AU2002329459A1 AU 2002329459 A1 AU2002329459 A1 AU 2002329459A1 AU 2002329459 A AU2002329459 A AU 2002329459A AU 2002329459 A AU2002329459 A AU 2002329459A AU 2002329459 A1 AU2002329459 A1 AU 2002329459A1
Authority
AU
Australia
Prior art keywords
azabicyclo
receptor antagonists
ether derivatives
neurokinin receptor
octane ether
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002329459A
Inventor
Neil Roy Curtis
Ian Thomas Huscroft
Janusz Jozef Kulagowski
Piotr Antoni Raubo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Pharma UK Ltd
Original Assignee
Merck Sharp and Dohme Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme Ltd filed Critical Merck Sharp and Dohme Ltd
Publication of AU2002329459A1 publication Critical patent/AU2002329459A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU2002329459A 2002-10-04 2002-10-04 8-azabicyclo(3.2.1)octane ether derivatives and their use as neurokinin receptor antagonists Abandoned AU2002329459A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB2002/004491 WO2004031185A1 (en) 2002-10-04 2002-10-04 8-azabicyclo[3.2.1]octane ether derivatives and their use as neurokinin receptor antagonists

Publications (1)

Publication Number Publication Date
AU2002329459A1 true AU2002329459A1 (en) 2004-04-23

Family

ID=32050693

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002329459A Abandoned AU2002329459A1 (en) 2002-10-04 2002-10-04 8-azabicyclo(3.2.1)octane ether derivatives and their use as neurokinin receptor antagonists

Country Status (4)

Country Link
EP (1) EP1551832A1 (en)
JP (1) JP2006508070A (en)
AU (1) AU2002329459A1 (en)
WO (1) WO2004031185A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005032209A1 (en) * 2005-07-09 2007-01-18 Lanxess Deutschland Gmbh New 1-cycloalkyl-5-iodotetrazole derivatives useful as microbicidal agent for the protection of plants and technical materials (e.g. wood) against infestation and/or destruction caused by microorganisms such as bacteria and fungus
CN112480107B (en) * 2020-11-30 2022-08-16 上海海雁医药科技有限公司 Substituted azabicyclooctane compounds, intermediates therefor and processes for their preparation

Also Published As

Publication number Publication date
WO2004031185A1 (en) 2004-04-15
JP2006508070A (en) 2006-03-09
EP1551832A1 (en) 2005-07-13

Similar Documents

Publication Publication Date Title
PL370972A1 (en) 1-alkyl-1-azoniabicyclo (2.2.2) octane carbamate derivatives and their use as muscarinic receptor antagonists
AU2003261392A1 (en) M3muscarinic acetylcholine receptor antagonists
IL198122A0 (en) Triazole derivatives as tachykinin receptor antagonists
HK1072052A1 (en) 3-azabicyclo (3.1.0) hexane derivatives as opioid receptor antagonists
HK1087703A1 (en) Substituted 1-piperidin-4-yl-4-pyrrolidin-3-yl-piperazine derivatives and their use as neurokinin antagonists
WO2004082623A3 (en) Substituted piperidine compounds
AU2003299807A1 (en) Heteroarylalkanoic acids as integrin receptor antagonists
IL152700A0 (en) Substituted 1-aminoalkyl-lactams and their use as muscarinc receptor antagonists
AU2003207460A1 (en) 3,4-di-substituted pyridazinediones as cxc chemokine receptor antagonists
AU2001264657A1 (en) Crf receptor antagonists
AU2003255501A1 (en) Cxcr4 receptor antagonists
WO2004112704A3 (en) Substituted piperidine compounds and methods of their use
AU2001290772A1 (en) Alpha v integrin receptor antagonists
AU2003267088A1 (en) Chemokine receptor antagonists as therapeutic agents
AU2441801A (en) Urotensin-ii receptor antagonists
HK1042699A1 (en) N-triazolylmethyl-piperazine derivatives as neurokinin receptor antagonists.
HK1045684A1 (en) Biphenyl derivatives as antagonists of the neurokinine-1 receptor.
HK1087924A1 (en) Substituted 1-piperidin-3-yl-4-piperidin-4-yl-piperazine derivatives and their use as neurokinin antagonists
AU2002226048A1 (en) Urotensin-ii receptor antagonists
HUP0200080A2 (en) 4-heterocyclysulfonamidyl-6-methoxy-5-(2-methoxy-phenoxy)-2-pyridyl-pyrimidine derivatives, their preparation and use as endothelin receptor antagonists and pharmaceutical compositions containing the compounds
AU2002239506A1 (en) Urotensin-ii receptor antagonists
AU3611099A (en) Oxindole derivatives used as neurokinin receptor antagonists
AU2004212165B2 (en) Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
AUPQ570100A0 (en) Beta-alanine derivatives and their use as receptor antagonists
AU2001249573A1 (en) Chemokine receptor antagonists

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase