AU2002258397A8 - Manufacture of thyroid hormone tablets having consistent active moiety amounts - Google Patents

Manufacture of thyroid hormone tablets having consistent active moiety amounts

Info

Publication number
AU2002258397A8
AU2002258397A8 AU2002258397A AU2002258397A AU2002258397A8 AU 2002258397 A8 AU2002258397 A8 AU 2002258397A8 AU 2002258397 A AU2002258397 A AU 2002258397A AU 2002258397 A AU2002258397 A AU 2002258397A AU 2002258397 A8 AU2002258397 A8 AU 2002258397A8
Authority
AU
Australia
Prior art keywords
manufacture
thyroid hormone
active moiety
consistent active
amounts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
AU2002258397A
Other versions
AU2002258397A1 (en
Inventor
Matthew Smith
Philip A Dimenna
Floyd Meredith
G Andrew Franz
Rocco L Gemma
Eliane A Strauss
Scott C Vaaler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
King Pharmaceuticals Inc
Original Assignee
King Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by King Pharmaceuticals Inc filed Critical King Pharmaceuticals Inc
Publication of AU2002258397A1 publication Critical patent/AU2002258397A1/en
Publication of AU2002258397A8 publication Critical patent/AU2002258397A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/60—Mixing solids with solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B01F25/4334—Mixers with a converging cross-section
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/80—Falling particle mixers, e.g. with repeated agitation along a vertical axis
    • B01F25/82—Falling particle mixers, e.g. with repeated agitation along a vertical axis uniting flows of material taken from different parts of a receptacle or from a set of different receptacles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Basic Packing Technique (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2002258397A 2001-02-15 2002-02-15 Manufacture of thyroid hormone tablets having consistent active moiety amounts Abandoned AU2002258397A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26899801P 2001-02-15 2001-02-15
US60/268,998 2001-02-15
PCT/US2002/004504 WO2002067854A2 (en) 2001-02-15 2002-02-15 Manufacture of thyroid hormone tablets having consistent active moiety amounts

Publications (2)

Publication Number Publication Date
AU2002258397A1 AU2002258397A1 (en) 2002-09-12
AU2002258397A8 true AU2002258397A8 (en) 2002-09-12

Family

ID=23025405

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002258397A Abandoned AU2002258397A1 (en) 2001-02-15 2002-02-15 Manufacture of thyroid hormone tablets having consistent active moiety amounts

Country Status (4)

Country Link
AU (1) AU2002258397A1 (en)
CA (1) CA2438907A1 (en)
MX (1) MXPA03007338A (en)
WO (1) WO2002067854A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6645526B2 (en) 2001-11-13 2003-11-11 Mylan Pharmaceuticals, Inc. Storage stable thyroxine active drug formulations and methods for their production
US20030099699A1 (en) 2001-11-13 2003-05-29 Hanshew Dwight D. Storage stable thyroxine active drug formulations and methods for their production
CA2708956C (en) 2007-12-18 2018-07-17 Athera Biotechnologies Ab Use of annexin a5 for the treatment of vascular disease
CN105612048A (en) 2013-06-27 2016-05-25 Gea工艺工程有限公司 Method for continuous production of tablets, tabletting system for carrying out the method, and use of the tabletting system for the production of tablets of at least two ingredients containing particles with a significant difference in particle size

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5099001A (en) * 1989-12-28 1992-03-24 Nepera, Inc. Process for the production of thyroglobulin
US5407339A (en) * 1993-09-27 1995-04-18 Vector Corporation Triturate tablet machine
US5672364A (en) * 1994-07-07 1997-09-30 Sankyo Seisakusho Co. & Eisai Co., Ltd. Apparatus for manufacturing tablets
US6117911A (en) * 1997-04-11 2000-09-12 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies

Also Published As

Publication number Publication date
CA2438907A1 (en) 2002-09-06
AU2002258397A1 (en) 2002-09-12
MXPA03007338A (en) 2005-06-06
WO2002067854A3 (en) 2004-04-15
WO2002067854A2 (en) 2002-09-06

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase