AU2002245474B2 - Monitoring soluble endothelial protein C receptor levels in anticoagulant therapy - Google Patents

Monitoring soluble endothelial protein C receptor levels in anticoagulant therapy Download PDF

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Publication number
AU2002245474B2
AU2002245474B2 AU2002245474A AU2002245474A AU2002245474B2 AU 2002245474 B2 AU2002245474 B2 AU 2002245474B2 AU 2002245474 A AU2002245474 A AU 2002245474A AU 2002245474 A AU2002245474 A AU 2002245474A AU 2002245474 B2 AU2002245474 B2 AU 2002245474B2
Authority
AU
Australia
Prior art keywords
sepcr
levels
anticoagulant therapy
protein
thrombin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2002245474A
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English (en)
Other versions
AU2002245474A1 (en
Inventor
Shinichiro Kurosawa
Deborah J. Stearns-Kurosawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oklahoma Medical Research Foundation
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Oklahoma Medical Research Foundation
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Filing date
Publication date
Application filed by Oklahoma Medical Research Foundation filed Critical Oklahoma Medical Research Foundation
Publication of AU2002245474A1 publication Critical patent/AU2002245474A1/en
Application granted granted Critical
Publication of AU2002245474B2 publication Critical patent/AU2002245474B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/22Haematology
    • G01N2800/224Haemostasis or coagulation

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU2002245474A 2001-02-20 2002-02-19 Monitoring soluble endothelial protein C receptor levels in anticoagulant therapy Ceased AU2002245474B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US27006601P 2001-02-20 2001-02-20
US60/270,066 2001-02-20
US10/028,741 2001-12-20
US10/028,741 US7169573B2 (en) 2001-02-20 2001-12-20 Method for monitoring coagulability and hypercoagulable states
PCT/US2002/005023 WO2002066981A2 (en) 2001-02-20 2002-02-19 Monitoring soluble endothelial protein c receptor levels in anticoagulant therapy

Publications (2)

Publication Number Publication Date
AU2002245474A1 AU2002245474A1 (en) 2003-02-27
AU2002245474B2 true AU2002245474B2 (en) 2007-05-17

Family

ID=26704034

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002245474A Ceased AU2002245474B2 (en) 2001-02-20 2002-02-19 Monitoring soluble endothelial protein C receptor levels in anticoagulant therapy

Country Status (6)

Country Link
US (1) US7169573B2 (https=)
EP (1) EP1368661A2 (https=)
JP (1) JP2004530114A (https=)
AU (1) AU2002245474B2 (https=)
CA (1) CA2438811A1 (https=)
WO (1) WO2002066981A2 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2941594C (en) * 2002-12-20 2021-07-06 Celera Corporation Genetic polymorphisms of the protein receptor c (procr) associated with myocardial infarction, methods of detection and uses thereof
US7906117B2 (en) * 2007-05-21 2011-03-15 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat cachexia, weakness, fatigue, and/or fever
US8062864B2 (en) 2007-05-21 2011-11-22 Alderbio Holdings Llc Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies
US8404235B2 (en) * 2007-05-21 2013-03-26 Alderbio Holdings Llc Antagonists of IL-6 to raise albumin and/or lower CRP
US8178101B2 (en) 2007-05-21 2012-05-15 Alderbio Holdings Inc. Use of anti-IL-6 antibodies having specific binding properties to treat cachexia
US9701747B2 (en) 2007-05-21 2017-07-11 Alderbio Holdings Llc Method of improving patient survivability and quality of life by anti-IL-6 antibody administration
US8252286B2 (en) 2007-05-21 2012-08-28 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat thrombosis
US20090238825A1 (en) * 2007-05-21 2009-09-24 Kovacevich Brian R Novel rabbit antibody humanization methods and humanized rabbit antibodies
HUE032563T2 (en) 2007-05-21 2017-09-28 Alderbio Holdings Llc Antibodies to IL-6 and their use
KR20170036814A (ko) * 2007-05-21 2017-04-03 앨더바이오 홀딩스 엘엘씨 신규한 래빗 항체 인간화 방법 및 인간화된 래빗 항체
US8277804B2 (en) * 2008-05-21 2012-10-02 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat thrombosis
US8992920B2 (en) 2008-11-25 2015-03-31 Alderbio Holdings Llc Anti-IL-6 antibodies for the treatment of arthritis
CA2744400C (en) * 2008-11-25 2019-01-15 Alder Biopharmaceuticals, Inc. Antibodies to il-6 and use thereof
US8337847B2 (en) 2008-11-25 2012-12-25 Alderbio Holdings Llc Methods of treating anemia using anti-IL-6 antibodies
US8420089B2 (en) 2008-11-25 2013-04-16 Alderbio Holdings Llc Antagonists of IL-6 to raise albumin and/or lower CRP
US9452227B2 (en) 2008-11-25 2016-09-27 Alderbio Holdings Llc Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments
US8323649B2 (en) 2008-11-25 2012-12-04 Alderbio Holdings Llc Antibodies to IL-6 and use thereof
US9212223B2 (en) 2008-11-25 2015-12-15 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat thrombosis
FR2948666A1 (fr) 2009-07-30 2011-02-04 Univ Paris Curie Methode de diagnostic d'un cancer et de determination de la severite d'un cancer chez un individu
WO2011066374A2 (en) 2009-11-24 2011-06-03 Alder Biopharmaceuticals, Inc. Antagonists of il-6 to prevent or treat cachexia, weakness, fatigue, and/or fever
US9775921B2 (en) 2009-11-24 2017-10-03 Alderbio Holdings Llc Subcutaneously administrable composition containing anti-IL-6 antibody
US9304134B2 (en) 2010-11-23 2016-04-05 Alderbio Holdings Llc Anti-IL-6 antibodies for the treatment of anemia
EP3673870A3 (en) * 2018-11-09 2020-09-09 Universite Paris Descartes Bioprosthetic tissues and heart valves coated with epcr
MX2022004558A (es) * 2019-10-17 2023-03-02 Nova Biomedical Corp Aparato de ensayo de coagulacion y metodos del mismo.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5804392A (en) * 1997-06-27 1998-09-08 Oklahoma Medical Research Foundation Diagnostic assays using soluble endothelial cell protein C/activated protein C receptor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5695993A (en) 1994-08-12 1997-12-09 Oklahoma Medical Research Foundation Cloning and regulation of an endothelial cell protein C/activated protein C receptor
WO2000007012A1 (en) * 1998-07-31 2000-02-10 Carroll Wallace E Method and apparatus for determining anticoagulant therapy factors
US5935802A (en) * 1998-08-10 1999-08-10 Evanston Northwestern Healthcare Research Institute Method of assaying a blood sample for prothrombin

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5804392A (en) * 1997-06-27 1998-09-08 Oklahoma Medical Research Foundation Diagnostic assays using soluble endothelial cell protein C/activated protein C receptor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Blood (1998) 91, page 725-727 *

Also Published As

Publication number Publication date
EP1368661A2 (en) 2003-12-10
CA2438811A1 (en) 2002-08-29
WO2002066981A3 (en) 2003-04-24
WO2002066981A2 (en) 2002-08-29
US7169573B2 (en) 2007-01-30
JP2004530114A (ja) 2004-09-30
US20060286614A1 (en) 2006-12-21

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Legal Events

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired