AU2002243280A1 - Engineered stimulus-responsive switches - Google Patents

Engineered stimulus-responsive switches

Info

Publication number
AU2002243280A1
AU2002243280A1 AU2002243280A AU4328002A AU2002243280A1 AU 2002243280 A1 AU2002243280 A1 AU 2002243280A1 AU 2002243280 A AU2002243280 A AU 2002243280A AU 4328002 A AU4328002 A AU 4328002A AU 2002243280 A1 AU2002243280 A1 AU 2002243280A1
Authority
AU
Australia
Prior art keywords
responsive switches
engineered stimulus
stimulus
engineered
responsive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002243280A
Inventor
Ruchira Das Gupta
Joseph Jacobson
John J. Schwartz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Engeneos Inc
Original Assignee
Engeneos Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Engeneos Inc filed Critical Engeneos Inc
Publication of AU2002243280A1 publication Critical patent/AU2002243280A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/635—Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/24—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a MBP (maltose binding protein)-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
    • C07K2319/81—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor containing a Zn-finger domain for DNA binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Peptides Or Proteins (AREA)
AU2002243280A 2000-10-23 2001-10-23 Engineered stimulus-responsive switches Abandoned AU2002243280A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24254600P 2000-10-23 2000-10-23
US60/242,546 2000-10-23
PCT/US2001/046273 WO2002048195A2 (en) 2000-10-23 2001-10-23 Engineered stimulus-responsive switches

Publications (1)

Publication Number Publication Date
AU2002243280A1 true AU2002243280A1 (en) 2002-06-24

Family

ID=22915209

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002243280A Abandoned AU2002243280A1 (en) 2000-10-23 2001-10-23 Engineered stimulus-responsive switches

Country Status (3)

Country Link
US (2) US20030049799A1 (en)
AU (1) AU2002243280A1 (en)
WO (1) WO2002048195A2 (en)

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US7020560B2 (en) * 2001-09-06 2006-03-28 University Of Tennessee Research Foundation Methods for cell-based combinatorial logic
WO2003089454A2 (en) * 2002-04-19 2003-10-30 California Institute Of Technology Unnatural amino acid containing display libraries
US20070031966A1 (en) * 2005-07-18 2007-02-08 Regents Of The University Of Michigan Renal progenitor cells from embryonic stem cells
KR100812110B1 (en) * 2006-10-24 2008-03-12 한국과학기술원 A preparation of an artificial transcription factor comprising zinc finger protein and transcription factor of prokaryote and an use thereof
US8645115B2 (en) 2008-12-22 2014-02-04 Trustees Of Boston University Modular nucleic acid-based circuits for counters, binary operations, memory and logic
WO2012170436A1 (en) * 2011-06-06 2012-12-13 The Regents Of The University Of California Synthetic biology tools
CN102559529B (en) * 2012-02-23 2013-08-21 山东大学 Yeast engineering bacterial strain capable of producing glutathione and application thereof in production of glutathione
EP3808844A1 (en) * 2012-07-25 2021-04-21 The Broad Institute, Inc. Inducible dna binding proteins and genome perturbation tools and applications thereof
WO2014093402A2 (en) * 2012-12-10 2014-06-19 The Regents Of The University Of California A synthetic transcription factor and uses thereof
US10847251B2 (en) 2013-01-17 2020-11-24 Illumina, Inc. Genomic infrastructure for on-site or cloud-based DNA and RNA processing and analysis
US10691775B2 (en) 2013-01-17 2020-06-23 Edico Genome, Corp. Bioinformatics systems, apparatuses, and methods executed on an integrated circuit processing platform
US9792405B2 (en) 2013-01-17 2017-10-17 Edico Genome, Corp. Bioinformatics systems, apparatuses, and methods executed on an integrated circuit processing platform
US10068054B2 (en) 2013-01-17 2018-09-04 Edico Genome, Corp. Bioinformatics systems, apparatuses, and methods executed on an integrated circuit processing platform
US9679104B2 (en) 2013-01-17 2017-06-13 Edico Genome, Corp. Bioinformatics systems, apparatuses, and methods executed on an integrated circuit processing platform
WO2015095796A1 (en) * 2013-12-20 2015-06-25 President And Fellows Of Harvard College An engineered genetic enteric sensor bacteria and uses thereof
WO2015123331A1 (en) * 2014-02-17 2015-08-20 Arizona Board Of Regents On Behalf Of Arizona State University A protein-based molecular temperature switch
WO2015127242A1 (en) * 2014-02-21 2015-08-27 President And Fellows Of Harvard College De novo design of allosteric proteins
US10020300B2 (en) 2014-12-18 2018-07-10 Agilome, Inc. Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids
US9618474B2 (en) 2014-12-18 2017-04-11 Edico Genome, Inc. Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids
US10006910B2 (en) 2014-12-18 2018-06-26 Agilome, Inc. Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same
EP3235010A4 (en) 2014-12-18 2018-08-29 Agilome, Inc. Chemically-sensitive field effect transistor
US9859394B2 (en) 2014-12-18 2018-01-02 Agilome, Inc. Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids
US9857328B2 (en) 2014-12-18 2018-01-02 Agilome, Inc. Chemically-sensitive field effect transistors, systems and methods for manufacturing and using the same
EP3259590A4 (en) * 2015-02-20 2018-10-17 Edico Genome, Corp. Bioinformatics systems, apparatuses, and methods executed on an integrated circuit processing platform
EP3329491A2 (en) 2015-03-23 2018-06-06 Edico Genome Corporation Method and system for genomic visualization
US10793840B2 (en) 2015-05-05 2020-10-06 William Marsh Rice University Identifying ligands for bacterial sensors
US20170270245A1 (en) 2016-01-11 2017-09-21 Edico Genome, Corp. Bioinformatics systems, apparatuses, and methods for performing secondary and/or tertiary processing
US10068183B1 (en) 2017-02-23 2018-09-04 Edico Genome, Corp. Bioinformatics systems, apparatuses, and methods executed on a quantum processing platform
CN107344962B (en) * 2016-05-04 2021-03-02 中国科学院微生物研究所 Repressor protein, regulatory element group, gene expression regulatory system and construction method thereof
EP3459115A4 (en) 2016-05-16 2020-04-08 Agilome, Inc. Graphene fet devices, systems, and methods of using the same for sequencing nucleic acids
PL3538665T3 (en) 2016-11-14 2024-05-06 PPB Technology Pty Ltd Protease sensor molecules
JP7265487B2 (en) * 2017-06-08 2023-04-26 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル Chimeric receptors for use in whole-cell sensors for detecting analytes of interest
KR102660777B1 (en) * 2017-08-08 2024-04-24 커먼웰쓰 사이언티픽 앤드 인더스트리얼 리서치 오가니제이션 carbohydrate sensor
CN112501091B (en) * 2019-09-16 2022-07-19 集美大学 Vibrio harveyi cheA gene silencing cell strain and application thereof
CN112011587A (en) * 2020-08-07 2020-12-01 华东理工大学 Erasable and rewritable living cell sensing recording system and application thereof

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WO1993023431A1 (en) * 1992-05-14 1993-11-25 Baylor College Of Medicine Mutated steroid hormone receptors, methods for their use and molecular switch for gene therapy
US5364791A (en) * 1992-05-14 1994-11-15 Elisabetta Vegeto Progesterone receptor having C. terminal hormone binding domain truncations
US5834266A (en) * 1993-02-12 1998-11-10 President & Fellows Of Harvard College Regulated apoptosis
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US5464758A (en) * 1993-06-14 1995-11-07 Gossen; Manfred Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters
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US8349602B1 (en) * 1996-04-19 2013-01-08 Xenogen Corporation Biodetectors targeted to specific ligands
US5739018A (en) * 1996-08-07 1998-04-14 The Regents Of The University Of California Packaging cell lines for pseudotyped retroviral vectors
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US6153383A (en) * 1997-12-09 2000-11-28 Verdine; Gregory L. Synthetic transcriptional modulators and uses thereof
ATE241830T1 (en) * 1998-02-20 2003-06-15 Us Gov Health & Human Serv MOLECULAR COMPUTING ELEMENTS: GATES AND FLIP-FLOPS
US6333318B1 (en) * 1998-05-14 2001-12-25 The Salk Institute For Biological Studies Formulations useful for modulating expression of exogenous genes in mammalian systems, and products related thereto
US5989910A (en) * 1998-08-03 1999-11-23 University Of Lausanne Potent genetic switch allowing regulated gene expression in eukaryotic cells
WO2000052179A2 (en) * 1999-03-03 2000-09-08 Genelabs Technologies, Inc. Dna binding compound-mediated molecular switch system
DE60219810D1 (en) * 2001-08-23 2007-06-06 Univ California UNIVERSAL, LIGHT SWITCHABLE GENERIC PROMOTER SYSTEM

Also Published As

Publication number Publication date
US20030049799A1 (en) 2003-03-13
US20070196816A1 (en) 2007-08-23
WO2002048195A3 (en) 2003-07-17
WO2002048195A2 (en) 2002-06-20

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