AU2002237928A1 - Methods and compositions for expressing polynucleotides specifically in smooth muscle cells in vivo - Google Patents

Methods and compositions for expressing polynucleotides specifically in smooth muscle cells in vivo

Info

Publication number
AU2002237928A1
AU2002237928A1 AU2002237928A AU2002237928A AU2002237928A1 AU 2002237928 A1 AU2002237928 A1 AU 2002237928A1 AU 2002237928 A AU2002237928 A AU 2002237928A AU 2002237928 A AU2002237928 A AU 2002237928A AU 2002237928 A1 AU2002237928 A1 AU 2002237928A1
Authority
AU
Australia
Prior art keywords
vivo
compositions
methods
smooth muscle
muscle cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002237928A
Other languages
English (en)
Inventor
Ichiro Manabe
Gary K. Owens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU2002237928A1 publication Critical patent/AU2002237928A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2002237928A 2001-01-24 2002-01-24 Methods and compositions for expressing polynucleotides specifically in smooth muscle cells in vivo Abandoned AU2002237928A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26381101P 2001-01-24 2001-01-24
US60/263,811 2001-01-24
PCT/US2002/002016 WO2002059270A2 (fr) 2001-01-24 2002-01-24 Procedes et compositions pour l'expression de polynucleotides specifiquement dans des cellules de muscle lisse in vivo

Publications (1)

Publication Number Publication Date
AU2002237928A1 true AU2002237928A1 (en) 2002-08-06

Family

ID=23003314

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002237928A Abandoned AU2002237928A1 (en) 2001-01-24 2002-01-24 Methods and compositions for expressing polynucleotides specifically in smooth muscle cells in vivo

Country Status (4)

Country Link
EP (1) EP1360191A4 (fr)
AU (1) AU2002237928A1 (fr)
CA (1) CA2435631A1 (fr)
WO (1) WO2002059270A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040234972A1 (en) * 2001-03-20 2004-11-25 Owens Gary K. Method for identifying and purifying smooth muscle progenitor cells
CN102676527B (zh) * 2012-05-29 2013-09-25 山东农业大学 一种骨骼肌特异性MYHC-IIx启动子及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9305091D0 (en) * 1993-03-12 1993-04-28 Thrombosis Res Inst Eukaryotic expression vectors driven by a novel strong mammalian cell promoter
DE19620308A1 (de) * 1996-05-10 1997-11-13 Franz Wolfgang M Dr Vektor-System zur spezifischen in vivo Genexpression in glatten Gefäßmuskelzellen
WO1999036101A1 (fr) * 1998-01-16 1999-07-22 The University Of Virginia Patent Foundation Identification d'un promoteur/activateur de chaines lourdes de myosine des muscles lisses (sm-mhc), specifique aux cellules musculaires lisses

Also Published As

Publication number Publication date
WO2002059270A8 (fr) 2003-11-06
EP1360191A2 (fr) 2003-11-12
EP1360191A4 (fr) 2004-08-25
CA2435631A1 (fr) 2002-08-01
WO2002059270A2 (fr) 2002-08-01
WO2002059270A3 (fr) 2003-03-27

Similar Documents

Publication Publication Date Title
EP1687452A4 (fr) Mimeticorps de noyau-charniere humain, compositions, procedes et applications correspondantes
GB2386375B (en) Polymer electrolyte composition and uses thereof
AU2003234336A1 (en) Methods and compositions for use in preparing sirnas
AU2003251888A1 (en) Microdermabrasion composition and kit
AU2002305346A1 (en) Techniques and compositions for treating cardiovascular disease by (in vivo) gene delivery
AU2002322211A1 (en) Methods and compisitions for activation human t cells in vitro
EP1440680A4 (fr) Composition cosmetique a base de polymeres et produits cosmetiques
AU2002306763A1 (en) Methods for identifying and purifying smooth muscle progenitor cells
AU2003212850A1 (en) Methods and compositions for treating cardiovascular disease
AU2002342087A1 (en) Compositions and methods for making mutations in cell lines and animals
AU2003266282A1 (en) Compositions comprising muscle progenitor cells and uses thereof
GB2384704B (en) Improvements in spatulas
AU2002306461A1 (en) In vivo delivery methods and compositions
AU2002248467A1 (en) Vegf-d expression in brain cancer
AU2001269803A1 (en) Compositions and methods for modulating muscle cell and tissue contractility
AU2002237928A1 (en) Methods and compositions for expressing polynucleotides specifically in smooth muscle cells in vivo
AU2003217222A1 (en) In vivo gene transfer
AU2002323137A1 (en) Methods and compositions for use in selectively producing a protein in telomerase expressing cells
AU2001253812A1 (en) In vivo loading of mhc
AU2002301354A1 (en) Improvements in Transmissometers
AU2002301358A1 (en) Improvements in Transmissometers
AU2003280648A1 (en) Cosmetics excellent in texture and oil-dispersibility
AU2002226986A1 (en) In vivo delivery methods and compositions
EP1369108A4 (fr) Composition utilisee dans l'electroporation
AU2002238794A1 (en) Methods and compositions involved in groucho-mediated differentiation

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase