AU2002237704A1 - Methods for the stereoselective synthesis of substituted piperidines - Google Patents

Methods for the stereoselective synthesis of substituted piperidines

Info

Publication number
AU2002237704A1
AU2002237704A1 AU2002237704A AU3770402A AU2002237704A1 AU 2002237704 A1 AU2002237704 A1 AU 2002237704A1 AU 2002237704 A AU2002237704 A AU 2002237704A AU 3770402 A AU3770402 A AU 3770402A AU 2002237704 A1 AU2002237704 A1 AU 2002237704A1
Authority
AU
Australia
Prior art keywords
methods
stereoselective synthesis
substituted piperidines
piperidines
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002237704A
Inventor
Brian M. Aquila
Thomas D. Bannister
Gregory D. Cuny
James R Hauske
Michele L. Hefferman
Michael Z. Hoemann
Donald W. Kessler
Liming Shao
Xinhe Wu
Roger L. Xie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sunovion Pharmaceuticals Inc
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sepracor Inc filed Critical Sepracor Inc
Publication of AU2002237704A1 publication Critical patent/AU2002237704A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2002237704A 2000-12-04 2001-12-04 Methods for the stereoselective synthesis of substituted piperidines Abandoned AU2002237704A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US25120900P 2000-12-04 2000-12-04
US60/251,209 2000-12-04
US27560001P 2001-03-13 2001-03-13
US60/275,600 2001-03-13
PCT/US2001/047037 WO2002046157A2 (en) 2000-12-04 2001-12-04 Methods for the stereoselective synthesis of substituted piperidines

Publications (1)

Publication Number Publication Date
AU2002237704A1 true AU2002237704A1 (en) 2002-06-18

Family

ID=26941482

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002237704A Abandoned AU2002237704A1 (en) 2000-12-04 2001-12-04 Methods for the stereoselective synthesis of substituted piperidines

Country Status (3)

Country Link
US (3) US6703508B2 (en)
AU (1) AU2002237704A1 (en)
WO (1) WO2002046157A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU9087301A (en) * 2000-09-11 2002-03-26 Sepracor Inc Ligands for monoamine receptors and transporters, and methods of use thereof
US7294637B2 (en) * 2000-09-11 2007-11-13 Sepracor, Inc. Method of treating addiction or dependence using a ligand for a monamine receptor or transporter
WO2003016274A2 (en) * 2001-08-21 2003-02-27 Sepracor, Inc. 2-substituted piperidines that are ligands for monoamine receptors and transporters
US7153858B2 (en) * 2003-01-31 2006-12-26 Epix Delaware, Inc. Arylpiperazinyl compounds
WO2006127649A2 (en) * 2005-05-22 2006-11-30 U.S. Borax Inc. Co-biocidal formulation for polymeric materials
US7977336B2 (en) 2006-12-28 2011-07-12 Banyu Pharmaceutical Co. Ltd Aminopyrimidine derivatives as PLK1 inhibitors

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3029244A (en) * 1959-08-31 1962-04-10 Research Corp Aroylpiperidinols and esters thereof
US4012396A (en) 1973-05-21 1977-03-15 Hoffmann-La Roche Inc. Processes and intermediates for cis or trans 2-or 3-(1-acyl-3-vinyl-4-piperidine)acetic or propionic acid esters
FR2649098A1 (en) 1989-06-29 1991-01-04 Centre Nat Rech Scient CHIRAL POLYMERS FOR THE SYNTHESIS OF ENANTIOMERICALLY PURE AMINOACIDES
US5332817A (en) 1990-01-04 1994-07-26 Pfizer Inc. 3-aminopiperidine derivatives and related nitrogen containing heterocycles
US5013842A (en) 1990-01-22 1991-05-07 Monsanto Company Synthesis of chiral pyrrolidine and piperidine glycosidase inhibitors
US5420283A (en) 1993-08-02 1995-05-30 Pfizer Inc. Resolution of (R)-2-benzylsuccinic acid 4-[4-(N-t-butoxycarbonylmethylamino)-piperidine] amide
US5972952A (en) 1995-12-11 1999-10-26 Le Centre National De La Recherche Scientifique Neuroprotective pharmaceutical composition containing stereoisomers of arylcyclohexylamines
US5952506A (en) 1997-04-24 1999-09-14 American Home Products Corporation Process for the synthesis of 4- 6- (hexylcarbamoyloxy) hexylcarbamoyloxy!-piperidine-1-carboxylic acid 4-phenoxyphenyl ester
US6521561B1 (en) 1998-05-01 2003-02-18 President And Fellows Of Harvard College Main-group metal based asymmetric catalysts and applications thereof
CA2372887A1 (en) 1999-05-25 2000-11-30 Sepracor Inc. Heterocyclic analgesic compounds and their use
CA2376957A1 (en) * 1999-06-30 2001-01-04 Merck & Co., Inc. Src kinase inhibitor compounds
AU2001216218A1 (en) 2000-05-25 2001-12-11 Sepracor, Inc. Heterocyclic analgesic compounds and method of use thereof

Also Published As

Publication number Publication date
US20040235893A1 (en) 2004-11-25
US7005524B2 (en) 2006-02-28
US20060211864A1 (en) 2006-09-21
US7692019B2 (en) 2010-04-06
US6703508B2 (en) 2004-03-09
WO2002046157A2 (en) 2002-06-13
WO2002046157A3 (en) 2003-02-27
US20020177721A1 (en) 2002-11-28

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