AU2002222218A1 - Cyclophilin-binding ligands - Google Patents
Cyclophilin-binding ligandsInfo
- Publication number
- AU2002222218A1 AU2002222218A1 AU2002222218A AU2221802A AU2002222218A1 AU 2002222218 A1 AU2002222218 A1 AU 2002222218A1 AU 2002222218 A AU2002222218 A AU 2002222218A AU 2221802 A AU2221802 A AU 2221802A AU 2002222218 A1 AU2002222218 A1 AU 2002222218A1
- Authority
- AU
- Australia
- Prior art keywords
- sup
- cyclophilin
- binding ligands
- bonds
- double
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/18—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Abstract
The present invention relates to a compound of formula I wherein (i) when a and c are double bonds, R<SUP>2 </SUP>is absent, b is a single bond, R<SUP>1 </SUP>is or (ii) when a and c are single bonds, b is a double bond, and R<SUP>1 </SUP>is H, R<SUP>2 </SUP>is wherein the substituents are as defined in the specification.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0030378.4A GB0030378D0 (en) | 2000-12-13 | 2000-12-13 | Compound |
GB0030378.4 | 2000-12-13 | ||
PCT/GB2001/005540 WO2002048178A2 (en) | 2000-12-13 | 2001-12-13 | Cyclophilin-binding ligands |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2002222218A1 true AU2002222218A1 (en) | 2002-06-24 |
Family
ID=9904993
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002222218A Abandoned AU2002222218A1 (en) | 2000-12-13 | 2001-12-13 | Cyclophilin-binding ligands |
Country Status (8)
Country | Link |
---|---|
US (1) | US7223795B2 (en) |
EP (1) | EP1343754B1 (en) |
AT (1) | ATE299492T1 (en) |
AU (1) | AU2002222218A1 (en) |
DE (1) | DE60111956T2 (en) |
ES (1) | ES2241744T3 (en) |
GB (1) | GB0030378D0 (en) |
WO (1) | WO2002048178A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0012528D0 (en) * | 2000-05-23 | 2000-07-12 | Univ Palackeho | Triterpenoid derivatives |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5234630B2 (en) * | 1974-06-07 | 1977-09-05 | ||
BE831558A (en) | 1975-07-18 | 1975-11-17 | IMPROVEMENT OF SMOKE AND HEAT EXHAUST OPENING DEVICES | |
GB9422383D0 (en) | 1994-11-05 | 1995-01-04 | Wellcome Found | Antibodies |
GB9509557D0 (en) | 1995-05-11 | 1995-07-05 | Univ Dundee | PCNA binding substance |
GB9519275D0 (en) | 1995-09-21 | 1995-11-22 | Univ Dundee | Substances and their therapeutic use |
DE69736351D1 (en) | 1996-05-08 | 2006-08-31 | Cyclacel Ltd | METHODS AND MEANS FOR INHIBITING CDK4 ACTIVITY |
AR010744A1 (en) | 1996-12-09 | 2000-07-12 | Guildford Pharmaceuticals Inc | CYCLOPHILINE POLYPROPYL INHIBITORS |
GB9812675D0 (en) | 1998-06-11 | 1998-08-12 | Univ Edinburgh | Peptides |
-
2000
- 2000-12-13 GB GBGB0030378.4A patent/GB0030378D0/en not_active Ceased
-
2001
- 2001-12-13 DE DE60111956T patent/DE60111956T2/en not_active Expired - Fee Related
- 2001-12-13 EP EP01270544A patent/EP1343754B1/en not_active Expired - Lifetime
- 2001-12-13 AU AU2002222218A patent/AU2002222218A1/en not_active Abandoned
- 2001-12-13 ES ES01270544T patent/ES2241744T3/en not_active Expired - Lifetime
- 2001-12-13 AT AT01270544T patent/ATE299492T1/en not_active IP Right Cessation
- 2001-12-13 WO PCT/GB2001/005540 patent/WO2002048178A2/en not_active Application Discontinuation
-
2003
- 2003-06-12 US US10/461,208 patent/US7223795B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1343754B1 (en) | 2005-07-13 |
GB0030378D0 (en) | 2001-01-24 |
US20040077829A1 (en) | 2004-04-22 |
EP1343754A2 (en) | 2003-09-17 |
US7223795B2 (en) | 2007-05-29 |
ATE299492T1 (en) | 2005-07-15 |
DE60111956T2 (en) | 2006-03-30 |
DE60111956D1 (en) | 2005-08-18 |
ES2241744T3 (en) | 2005-11-01 |
WO2002048178A2 (en) | 2002-06-20 |
WO2002048178A3 (en) | 2002-11-14 |
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