AU2002221772A1 - Derivatives of the human macrophage-migration inhibition factor (mif) and use thereof in pharmaceutical preparations in screening methods or the identification of analogues, agonists and antagonists - Google Patents

Derivatives of the human macrophage-migration inhibition factor (mif) and use thereof in pharmaceutical preparations in screening methods or the identification of analogues, agonists and antagonists

Info

Publication number
AU2002221772A1
AU2002221772A1 AU2002221772A AU2177202A AU2002221772A1 AU 2002221772 A1 AU2002221772 A1 AU 2002221772A1 AU 2002221772 A AU2002221772 A AU 2002221772A AU 2177202 A AU2177202 A AU 2177202A AU 2002221772 A1 AU2002221772 A1 AU 2002221772A1
Authority
AU
Australia
Prior art keywords
mif
derivatives
agonists
analogues
antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002221772A
Inventor
Jurgen Bernhagen
Herwig Brunner
Afroditi Kapurniotu
Robert Kleemann
Ralf Mischke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung eV
Original Assignee
Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7661895&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2002221772(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung eV filed Critical Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung eV
Publication of AU2002221772A1 publication Critical patent/AU2002221772A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Abstract

The invention relates to derivatives of the Migration Inhibition Factor (MIF), whereby the oxidoreductase centre is modified and use thereof.
AU2002221772A 2000-11-02 2001-10-29 Derivatives of the human macrophage-migration inhibition factor (mif) and use thereof in pharmaceutical preparations in screening methods or the identification of analogues, agonists and antagonists Abandoned AU2002221772A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10054303.0 2000-11-02
DE10054303A DE10054303B4 (en) 2000-11-02 2000-11-02 Analogs, agonists, antagonists and variants of the macrosurbed migration inhibitory factor (MIF) oxidoreductase enzyme activity as immunomodulators, therapeutics, diagnostics and screening agents in inflammatory and immune disorders
PCT/EP2001/012476 WO2002036774A2 (en) 2000-11-02 2001-10-29 Derivatives of the human macrophage-migration inhibition factor (mif) and use thereof in pharmaceutical preparations in screening methods or the identification of analogues, agonists and antagonists

Publications (1)

Publication Number Publication Date
AU2002221772A1 true AU2002221772A1 (en) 2002-05-15

Family

ID=7661895

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002221772A Abandoned AU2002221772A1 (en) 2000-11-02 2001-10-29 Derivatives of the human macrophage-migration inhibition factor (mif) and use thereof in pharmaceutical preparations in screening methods or the identification of analogues, agonists and antagonists

Country Status (9)

Country Link
EP (1) EP1334195B1 (en)
AT (1) ATE357521T1 (en)
AU (1) AU2002221772A1 (en)
CY (1) CY1106527T1 (en)
DE (2) DE10054303B4 (en)
DK (1) DK1334195T3 (en)
ES (1) ES2283458T3 (en)
PT (1) PT1334195E (en)
WO (1) WO2002036774A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19957065B4 (en) 1999-11-26 2005-01-05 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Screening procedure for drugs
WO2013010955A1 (en) 2011-07-15 2013-01-24 Morphosys Ag Antibodies that are cross-reactive for macrophage migration inhibitory factor (mif) and d-dopachrome tautomerase (d-dt)
WO2015071416A2 (en) * 2013-11-14 2015-05-21 Baxter Healthcare Sa Mif as therapeutic target

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5910427A (en) * 1995-06-22 1999-06-08 La Jolla Institute For Allergy And Immunology Antigen non-specific glycosylation inhibiting factor derivatives
DE19957065B4 (en) * 1999-11-26 2005-01-05 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Screening procedure for drugs

Also Published As

Publication number Publication date
PT1334195E (en) 2007-06-21
CY1106527T1 (en) 2012-01-25
EP1334195A2 (en) 2003-08-13
DE50112240D1 (en) 2007-05-03
ATE357521T1 (en) 2007-04-15
WO2002036774A2 (en) 2002-05-10
DK1334195T3 (en) 2007-07-30
DE10054303B4 (en) 2007-11-08
EP1334195B1 (en) 2007-03-21
ES2283458T3 (en) 2007-11-01
DE10054303A1 (en) 2002-05-16
WO2002036774A3 (en) 2002-12-12

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