AU2002217893A1 - Universal supports for oligonucleotide synthesis - Google Patents

Universal supports for oligonucleotide synthesis

Info

Publication number
AU2002217893A1
AU2002217893A1 AU2002217893A AU1789302A AU2002217893A1 AU 2002217893 A1 AU2002217893 A1 AU 2002217893A1 AU 2002217893 A AU2002217893 A AU 2002217893A AU 1789302 A AU1789302 A AU 1789302A AU 2002217893 A1 AU2002217893 A1 AU 2002217893A1
Authority
AU
Australia
Prior art keywords
oligonucleotide synthesis
universal supports
universal
supports
oligonucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002217893A
Inventor
Maxim Antopolskii
Alex Azhayev
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glen Research LLC
Original Assignee
Glen Research LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glen Research LLC filed Critical Glen Research LLC
Publication of AU2002217893A1 publication Critical patent/AU2002217893A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00452—Means for the recovery of reactants or products
    • B01J2219/00454—Means for the recovery of reactants or products by chemical cleavage from the solid support
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/005—Beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Structural Engineering (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
AU2002217893A 2000-11-29 2001-11-29 Universal supports for oligonucleotide synthesis Abandoned AU2002217893A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25375000P 2000-11-29 2000-11-29
US60/253,750 2000-11-29
PCT/US2001/044326 WO2002044398A2 (en) 2000-11-29 2001-11-29 Universal supports for oligonucleotide synthesis

Publications (1)

Publication Number Publication Date
AU2002217893A1 true AU2002217893A1 (en) 2002-06-11

Family

ID=22961550

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002217893A Abandoned AU2002217893A1 (en) 2000-11-29 2001-11-29 Universal supports for oligonucleotide synthesis

Country Status (4)

Country Link
US (2) US6770754B2 (en)
EP (2) EP1404695B1 (en)
AU (1) AU2002217893A1 (en)
WO (1) WO2002044398A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002217893A1 (en) * 2000-11-29 2002-06-11 Glen Research Corporation Universal supports for oligonucleotide synthesis
US20040054161A1 (en) * 2002-09-13 2004-03-18 Glen Research Corporation Stepwise solid-phase synthesis of peptide-oligonucleotide conjugates and supports therefor
CA2667714C (en) 2006-10-27 2014-09-09 Metkinen Chemistry Oy Carbamoylation of amines, thiophenols, mercaptanes and phenols employing organic azides
EP2525905B1 (en) 2010-01-19 2020-11-04 Illumina, Inc. Methods and compositions for processing chemical reactions
CN103237805B (en) 2010-08-23 2016-10-19 皇家学习促进学会/麦吉尔大学 The block synthesis of oligoribonucleotide
US9920084B2 (en) 2011-08-23 2018-03-20 The Royal Institution For The Advancement Of Learning/Mcgill University Ionic tags for synthesis of oligoribonucleotides
IL291323B2 (en) 2016-07-15 2023-09-01 Am Chemicals Llc Non-nucleosidic solid supports and phosphoramidite building blocks for oligonucleotide synthesis
CN115135663A (en) 2020-02-24 2022-09-30 合成Dna技术公司 Oligonucleotide synthesis on solid support
WO2023113038A1 (en) * 2021-12-17 2023-06-22 リードファーマ株式会社 Oligonucleotide production method

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5112962A (en) * 1989-04-19 1992-05-12 Northwestern University Labile anchors for solid phase polynucleotide synthesis
US6346413B1 (en) 1989-06-07 2002-02-12 Affymetrix, Inc. Polymer arrays
WO1992003464A1 (en) * 1990-08-28 1992-03-05 Microprobe Corporation Solid support synthesis of 3'-tailed oligonucleotides via a linking molecule
GB9207380D0 (en) 1992-04-03 1992-05-13 Ici Plc Compounds
US6312894B1 (en) * 1995-04-03 2001-11-06 Epoch Pharmaceuticals, Inc. Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders
US6316616B1 (en) * 1998-04-02 2001-11-13 President And Fellows Of Harvard College Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof
US6300070B1 (en) 1999-06-04 2001-10-09 Mosaic Technologies, Inc. Solid phase methods for amplifying multiple nucleic acids
AU2002217893A1 (en) * 2000-11-29 2002-06-11 Glen Research Corporation Universal supports for oligonucleotide synthesis

Also Published As

Publication number Publication date
EP1404695A2 (en) 2004-04-07
EP1404695B1 (en) 2013-04-10
US20020137855A1 (en) 2002-09-26
EP2248820A1 (en) 2010-11-10
US7491817B2 (en) 2009-02-17
US6770754B2 (en) 2004-08-03
WO2002044398A2 (en) 2002-06-06
US20050250116A1 (en) 2005-11-10
WO2002044398A3 (en) 2004-01-08
EP2248820B1 (en) 2014-01-08

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