AU2001298029A1 - Derivatives of the (3s, 4ar, 6s, 8ar) 6-phenylamino-1, 2, 3, 4, 4a, 5, 6, 7, 8, 8a-decahydro isoquinoline-3-carboxylic acid as excitatory amino acid receptor antagonists for the treatment of neurological disorders and neurodegenerative diseases - Google Patents

Derivatives of the (3s, 4ar, 6s, 8ar) 6-phenylamino-1, 2, 3, 4, 4a, 5, 6, 7, 8, 8a-decahydro isoquinoline-3-carboxylic acid as excitatory amino acid receptor antagonists for the treatment of neurological disorders and neurodegenerative diseases

Info

Publication number
AU2001298029A1
AU2001298029A1 AU2001298029A AU2001298029A AU2001298029A1 AU 2001298029 A1 AU2001298029 A1 AU 2001298029A1 AU 2001298029 A AU2001298029 A AU 2001298029A AU 2001298029 A AU2001298029 A AU 2001298029A AU 2001298029 A1 AU2001298029 A1 AU 2001298029A1
Authority
AU
Australia
Prior art keywords
phenylamino
derivatives
treatment
receptor antagonists
neurodegenerative diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001298029A
Other languages
English (en)
Inventor
Thomas John Bleisch
Ana Maria Castano Mansanet
Esteban Dominguez-Manzanares
Ana Maria Escribano
Paul Leslie Ornstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of AU2001298029A1 publication Critical patent/AU2001298029A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001298029A 2001-01-05 2001-12-19 Derivatives of the (3s, 4ar, 6s, 8ar) 6-phenylamino-1, 2, 3, 4, 4a, 5, 6, 7, 8, 8a-decahydro isoquinoline-3-carboxylic acid as excitatory amino acid receptor antagonists for the treatment of neurological disorders and neurodegenerative diseases Abandoned AU2001298029A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01500003.7 2001-01-05
EP01500003 2001-01-05
PCT/US2001/045858 WO2003024934A2 (fr) 2001-01-05 2001-12-19 Antagonistes des recepteurs d'aminoacides excitatoires

Publications (1)

Publication Number Publication Date
AU2001298029A1 true AU2001298029A1 (en) 2003-04-01

Family

ID=8183455

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001298029A Abandoned AU2001298029A1 (en) 2001-01-05 2001-12-19 Derivatives of the (3s, 4ar, 6s, 8ar) 6-phenylamino-1, 2, 3, 4, 4a, 5, 6, 7, 8, 8a-decahydro isoquinoline-3-carboxylic acid as excitatory amino acid receptor antagonists for the treatment of neurological disorders and neurodegenerative diseases

Country Status (3)

Country Link
EP (1) EP1351689A2 (fr)
AU (1) AU2001298029A1 (fr)
WO (1) WO2003024934A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2398225T3 (es) 2002-04-26 2013-03-14 Eli Lilly And Company Derivados de éster de un ácido DECAHIDROISOQUINOLIN-3-CARBOXÍLICO como analgésicos
CA2623759A1 (fr) * 2005-10-06 2007-04-19 Exelixis, Inc. Inhibiteurs de pim-1 et/ou de pim-3 a base de pyridopyrimidinone

Also Published As

Publication number Publication date
WO2003024934A3 (fr) 2003-07-24
WO2003024934A2 (fr) 2003-03-27
EP1351689A2 (fr) 2003-10-15

Similar Documents

Publication Publication Date Title
AU2002252373A1 (en) Methods and compositions for the treatment and/or diagnosis of neurological diseases and disorders
WO2003033720A8 (fr) Proteine a base de variants de tnf-alpha pour le traitement de troubles associes au tnf-alpha
AU1474001A (en) Compositions and methods for treatment of neurological disorders and neurodegenerative diseases
AU2002327378A1 (en) Treatment of neuropsychiatric disorders by near-diaphragmatic nerve stimulation
EP1511730B8 (fr) Derives de diaryle-uree utilises pour le traitement des maladies dependant des proteines kinases
IL169091A0 (en) Benzazepine derivatives for the treatment of neurological disorders
AU2003291992A1 (en) Phenylethanolamine derivatives for the treatment of respiratory diseases
AU2003285091A1 (en) Interferon antagonists useful for the treatment of interferon related diseases
AU2002356525A1 (en) Substituted amines for the treatment of neurological disorders
EP1897550A3 (fr) Promédicaments d'acides amines excitateurs
AU2002334870B8 (en) Combinations for the treatment of immunoinflammatory disorders
WO2001098279A3 (fr) Bis-arylsulfones
AU6205700A (en) Azo amino acid derivatives for the treatment of neurological diseases
AU2002240359A1 (en) Pharmaceutical composition for the treatment of alopecia
HUP0303751A3 (en) Use of n-phenyl-2-pyrimidineamine derivatives for preparation of pharmaceutical compositions suitable for treating mast cell-based diseases like allergic disorders
HK1080859A1 (en) Novel piperazinyl-pyrazinone derivatives for the treatment of 5-ht2a receptor-related disorders
AU2002362115A1 (en) Composition and methods for treatment of neurological disorders
AU2002227895A1 (en) Sulphonamides for the treatment of central nervous system diseases
AU5912900A (en) Quinuclidine derivatives for treatment of neurological disorders
HK1057332A1 (en) Use of 3-benzoylphenylacetic acid derivatives for the treatment of retinal disorders
AU2001298029A1 (en) Derivatives of the (3s, 4ar, 6s, 8ar) 6-phenylamino-1, 2, 3, 4, 4a, 5, 6, 7, 8, 8a-decahydro isoquinoline-3-carboxylic acid as excitatory amino acid receptor antagonists for the treatment of neurological disorders and neurodegenerative diseases
IL160852A0 (en) Pharmaceutical compositions for the treatment of urinary disorders
AU6076000A (en) Cyclic amine derivatives for the treatment of neurological diseases
WO2002080911A3 (fr) Utilisation de composes imidazo[1,2-a]-pyridine-3-yl-amide- et imidazo[1,2-a]-pyridine-3-yl-amine substitues comme medicaments
AU2003273856A1 (en) Vr1 antagonists for the treatment of urological disorders

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase