AU2001294365A1 - Process for the preparation of a beta-lactam nucleus and the application thereof - Google Patents

Process for the preparation of a beta-lactam nucleus and the application thereof

Info

Publication number
AU2001294365A1
AU2001294365A1 AU2001294365A AU9436501A AU2001294365A1 AU 2001294365 A1 AU2001294365 A1 AU 2001294365A1 AU 2001294365 A AU2001294365 A AU 2001294365A AU 9436501 A AU9436501 A AU 9436501A AU 2001294365 A1 AU2001294365 A1 AU 2001294365A1
Authority
AU
Australia
Prior art keywords
beta
preparation
application
lactam nucleus
lactam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001294365A
Inventor
Jeroen Den Hollander
Marjon Diender
Joseph Johannes Heijnen
Rienk Hendrik Kuipers
Adrianus Straathof
Thomas Van Der Does
Luuk Van Der Wielen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke DSM NV
Original Assignee
DSM NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM NV filed Critical DSM NV
Publication of AU2001294365A1 publication Critical patent/AU2001294365A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/84Penicillin amidase (3.5.1.11)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/02Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by desacylation of the substituent in the 7 position
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • C12P37/06Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by desacylation of the substituent in the 6 position

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2001294365A 2000-08-28 2001-08-27 Process for the preparation of a beta-lactam nucleus and the application thereof Abandoned AU2001294365A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NL1016032 2000-08-28
NL1016032 2000-08-28
PCT/NL2001/000626 WO2002018618A2 (en) 2000-08-28 2001-08-27 PROCESS FOR THE PREPARATION OF A β-LACTAM NUCLEUS AND THE APPLICATION THEREOF

Publications (1)

Publication Number Publication Date
AU2001294365A1 true AU2001294365A1 (en) 2002-03-13

Family

ID=19771964

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001294365A Abandoned AU2001294365A1 (en) 2000-08-28 2001-08-27 Process for the preparation of a beta-lactam nucleus and the application thereof

Country Status (7)

Country Link
US (1) US20040053912A1 (en)
EP (1) EP1319087A2 (en)
CN (1) CN1303217C (en)
AU (1) AU2001294365A1 (en)
EG (1) EG22838A (en)
MX (1) MXPA03001712A (en)
WO (1) WO2002018618A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2535893C1 (en) * 2013-08-20 2014-12-20 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика") Method for obtaining heterogenic biocatalyst based on hydrolase of esters of alpha aminoacids, heterogenic biocatalyst obtained by such method, and synthesis method of aminobeta-lactam antibiotic under action of this heterogenic biocatalyst

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1473100A (en) * 1973-05-10 1977-05-11
DE3724722A1 (en) * 1987-07-25 1989-02-16 Hoechst Ag IMPROVED METHOD FOR THE ENZYMATIC PRODUCTION OF L-2-AMINO-4-METHYLPHOSPHINOBUTTERIC ACID
RU2223323C2 (en) * 1997-04-22 2004-02-10 Дсм Н.В. Method for preparing 6-aminopenicillanic acid (6-apa)
AU8799498A (en) * 1997-06-10 1998-12-30 Gist-Brocades B.V. Process for enzymatically preparing a beta-lactam antibiotic and this antibiotic
GB9718740D0 (en) * 1997-09-05 1997-11-12 Advanced Phytonics Ltd Improvements in or relating to the preparation of a compound
JP3041337B2 (en) * 1998-02-16 2000-05-15 マンドー クライミット コントロール コーポレーション Pickle refrigerator operation control method

Also Published As

Publication number Publication date
WO2002018618A2 (en) 2002-03-07
EG22838A (en) 2003-09-30
MXPA03001712A (en) 2004-09-10
US20040053912A1 (en) 2004-03-18
CN1303217C (en) 2007-03-07
EP1319087A2 (en) 2003-06-18
CN1449450A (en) 2003-10-15
WO2002018618A3 (en) 2002-05-30

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