AU2001292582A1 - C-nitroso compounds and use thereof - Google Patents

C-nitroso compounds and use thereof

Info

Publication number
AU2001292582A1
AU2001292582A1 AU2001292582A AU9258201A AU2001292582A1 AU 2001292582 A1 AU2001292582 A1 AU 2001292582A1 AU 2001292582 A AU2001292582 A AU 2001292582A AU 9258201 A AU9258201 A AU 9258201A AU 2001292582 A1 AU2001292582 A1 AU 2001292582A1
Authority
AU
Australia
Prior art keywords
nitroso compounds
nitroso
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001292582A
Inventor
Jonathan S Stamler
Eric J. Toone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duke University
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duke University filed Critical Duke University
Publication of AU2001292582A1 publication Critical patent/AU2001292582A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C207/00—Compounds containing nitroso groups bound to a carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Materials For Medical Uses (AREA)
AU2001292582A 2000-10-26 2001-09-27 C-nitroso compounds and use thereof Abandoned AU2001292582A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/695,934 US6359182B1 (en) 2000-10-26 2000-10-26 C-nitroso compounds and use thereof
US09695934 2000-10-26
US09/695,934 2000-10-26
PCT/US2001/027734 WO2002034705A2 (en) 2000-10-26 2001-09-27 C-nitroso compounds and use thereof

Publications (1)

Publication Number Publication Date
AU2001292582A1 true AU2001292582A1 (en) 2002-05-06

Family

ID=24795034

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001292582A Abandoned AU2001292582A1 (en) 2000-10-26 2001-09-27 C-nitroso compounds and use thereof

Country Status (7)

Country Link
US (4) US6359182B1 (en)
EP (1) EP1330425B1 (en)
JP (1) JP2004512318A (en)
AU (1) AU2001292582A1 (en)
CA (1) CA2422787A1 (en)
DE (1) DE60128940T2 (en)
WO (1) WO2002034705A2 (en)

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US20040122011A1 (en) * 1998-12-23 2004-06-24 Pharmacia Corporation Method of using a COX-2 inhibitor and a TACE inhibitors as a combination therapy
EP1333823B1 (en) 2000-10-16 2010-03-31 Duke University Therapeutic use of aerosolized s-nitrosoglutathione in cystic fibrosis
US6359182B1 (en) * 2000-10-26 2002-03-19 Duke University C-nitroso compounds and use thereof
US7049308B2 (en) * 2000-10-26 2006-05-23 Duke University C-nitroso compounds and use thereof
US6627602B2 (en) 2001-11-13 2003-09-30 Duke University Preventing desensitization of receptors
US20060153931A1 (en) * 2001-12-06 2006-07-13 Stamler Jonathan S Prevention of flap necrosis in plastic surgery
US20030220374A1 (en) * 2002-01-14 2003-11-27 Pharmacia Corporation Compositions and methods of treatment involving peroxisome proliferator-activated receptor-gamma agonists and cyclooxygenase-2 selective inhibitors
US20030212138A1 (en) * 2002-01-14 2003-11-13 Pharmacia Corporation Combinations of peroxisome proliferator-activated receptor-alpha agonists and cyclooxygenase-2 selective inhibitors and therapeutic uses therefor
US20040147581A1 (en) * 2002-11-18 2004-07-29 Pharmacia Corporation Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy
WO2004050639A2 (en) * 2002-12-03 2004-06-17 Epcellon, Inc. 5-nitroso-6-piperazinyl-pyrimidine derivatives for treating ischemia
AU2003303041B2 (en) 2002-12-13 2008-07-24 Warner-Lambert Company Llc Alpha-2-delta ligand to treat lower urinary tract symptoms
WO2004062598A2 (en) * 2003-01-13 2004-07-29 Beta Pharma, Inc. Anti-inflammatory and anti-thrombotic compounds and their compositions
US20040220155A1 (en) * 2003-03-28 2004-11-04 Pharmacia Corporation Method of providing a steroid-sparing benefit with a cyclooxygenase-2 inhibitor and compositions therewith
US20050014729A1 (en) * 2003-07-16 2005-01-20 Pharmacia Corporation Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith
US20050119262A1 (en) * 2003-08-21 2005-06-02 Pharmacia Corporation Method for preventing or treating an optic neuropathy with a cox-2 inhibitor and an intraocular pressure reducing agent
US20050107350A1 (en) * 2003-08-22 2005-05-19 Pharmacia Corporation Method for the treatment or prevention of bone disorders with a cyclooxygenase-2 inhibitor alone and in combination with a bone disorder treatment agent and compositions therewith
US20050187278A1 (en) * 2003-08-28 2005-08-25 Pharmacia Corporation Treatment or prevention of vascular disorders with Cox-2 inhibitors in combination with cyclic AMP-specific phosphodiesterase inhibitors
US20050113409A1 (en) * 2003-09-03 2005-05-26 Pharmacia Corporation Method for the prevention or treatment of pain, inflammation and inflammation-related disorders with a Cox-2 selective inhibitor in combination with a nitric oxide-donating agent and compositions therewith
WO2005079808A1 (en) 2004-01-22 2005-09-01 Pfizer Limited Triazole derivatives which inhibit vasopressin antagonistic activity
JP4738352B2 (en) * 2004-02-09 2011-08-03 アミュレット ファーマシューティカルズ インコーポレイティッド Nitric oxide releasing polymer
US8470417B2 (en) 2004-04-02 2013-06-25 Curwood, Inc. Packaging inserts with myoglobin blooming agents, packages and methods for packaging
US8741402B2 (en) 2004-04-02 2014-06-03 Curwood, Inc. Webs with synergists that promote or preserve the desirable color of meat
US8029893B2 (en) 2004-04-02 2011-10-04 Curwood, Inc. Myoglobin blooming agent, films, packages and methods for packaging
US7867531B2 (en) 2005-04-04 2011-01-11 Curwood, Inc. Myoglobin blooming agent containing shrink films, packages and methods for packaging
US8053047B2 (en) 2004-04-02 2011-11-08 Curwood, Inc. Packaging method that causes and maintains the preferred red color of fresh meat
US8110259B2 (en) 2004-04-02 2012-02-07 Curwood, Inc. Packaging articles, films and methods that promote or preserve the desirable color of meat
US8545950B2 (en) 2004-04-02 2013-10-01 Curwood, Inc. Method for distributing a myoglobin-containing food product
US7067659B2 (en) * 2004-04-23 2006-06-27 Duke University Reactive oxygen generating enzyme inhibitor with nitric oxide bioactivity and uses thereof
JP2007534740A (en) * 2004-04-28 2007-11-29 ファイザー・インク 3-Heterocyclyl-4-phenyl-triazole derivatives as inhibitors of vasopressin V1a receptor
US20090214618A1 (en) 2005-05-27 2009-08-27 Schoenfisch Mark H Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications
JP2009518516A (en) * 2005-12-06 2009-05-07 アミュレット ファーマシューティカルズ インコーポレイティッド Nitric oxide releasing polymer
US7686448B2 (en) * 2006-06-16 2010-03-30 Marie Betts-Johnson Eyeglass frames
US11229746B2 (en) 2006-06-22 2022-01-25 Excelsior Medical Corporation Antiseptic cap
US9259535B2 (en) 2006-06-22 2016-02-16 Excelsior Medical Corporation Antiseptic cap equipped syringe
US20080025972A1 (en) * 2006-07-26 2008-01-31 Duke University Treating sex steriod responsive disorders
CA2673545A1 (en) 2006-12-22 2008-07-03 Recordati Ireland Limited Combination therapy of lower urinary tract disorders with .alpha.2.delta. ligands and nsaids
US7935847B2 (en) * 2007-04-20 2011-05-03 Duke University Nitroxyl ion source with second order reaction nitroxyl release
US8598368B2 (en) * 2007-04-20 2013-12-03 Duke University Stable neutral nitric oxide source
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US9078992B2 (en) 2008-10-27 2015-07-14 Pursuit Vascular, Inc. Medical device for applying antimicrobial to proximal end of catheter
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EP2468269A1 (en) 2010-11-26 2012-06-27 Universitätsklinikum Münster Nitric oxide donors in therapy of nitric oxide deficiency-induced disturbances of cerebral microcirculation
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
JP5990187B2 (en) 2010-12-16 2016-09-07 ニヴァリス・セラピューティクス・インコーポレーテッド Novel substituted bicyclic aromatic compounds as S-nitrosoglutathione reductase inhibitors
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US10046156B2 (en) 2014-05-02 2018-08-14 Excelsior Medical Corporation Strip package for antiseptic cap
AU2016262400B2 (en) 2015-05-08 2021-01-21 Icu Medical, Inc. Medical connectors configured to receive emitters of therapeutic agents
KR102613907B1 (en) 2015-09-09 2023-12-13 비욘드 에어 리미티드 Nitric oxide inhalation therapy for infants with bronchiolitis
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GB9423868D0 (en) * 1994-11-25 1995-01-11 Wellcome Found Compounds for use in medicine
GB9424694D0 (en) * 1994-12-07 1995-02-01 Wellcome Found Compounds for use in medicine
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US6359182B1 (en) * 2000-10-26 2002-03-19 Duke University C-nitroso compounds and use thereof

Also Published As

Publication number Publication date
DE60128940T2 (en) 2008-02-21
US6359182B1 (en) 2002-03-19
WO2002034705A3 (en) 2002-07-11
WO2002034705A2 (en) 2002-05-02
US6538116B2 (en) 2003-03-25
US20020077506A1 (en) 2002-06-20
US20050203295A1 (en) 2005-09-15
US20030176668A1 (en) 2003-09-18
CA2422787A1 (en) 2002-05-02
EP1330425B1 (en) 2007-06-13
US6887994B2 (en) 2005-05-03
DE60128940D1 (en) 2007-07-26
EP1330425A2 (en) 2003-07-30
JP2004512318A (en) 2004-04-22
US7030238B2 (en) 2006-04-18

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