AU2001289000A1 - Design and production of mutant 2,5-diketo-d-gluconic acid reductase enzymes with altered cofactor dependency - Google Patents

Design and production of mutant 2,5-diketo-d-gluconic acid reductase enzymes with altered cofactor dependency

Info

Publication number
AU2001289000A1
AU2001289000A1 AU2001289000A AU8900001A AU2001289000A1 AU 2001289000 A1 AU2001289000 A1 AU 2001289000A1 AU 2001289000 A AU2001289000 A AU 2001289000A AU 8900001 A AU8900001 A AU 8900001A AU 2001289000 A1 AU2001289000 A1 AU 2001289000A1
Authority
AU
Australia
Prior art keywords
diketo
mutant
design
production
gluconic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001289000A
Inventor
Stephen Anderson
Scott Banta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rutgers State University of New Jersey
Original Assignee
Rutgers State University of New Jersey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rutgers State University of New Jersey filed Critical Rutgers State University of New Jersey
Publication of AU2001289000A1 publication Critical patent/AU2001289000A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2001289000A 2000-09-11 2001-09-11 Design and production of mutant 2,5-diketo-d-gluconic acid reductase enzymes with altered cofactor dependency Abandoned AU2001289000A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/658,645 US6423518B1 (en) 2000-09-11 2000-09-11 Design and production of mutant 2,5-diketo-D-gluconic acid reductase enzymes with altered cofactor dependency
US09/658,645 2000-09-11
PCT/US2001/028366 WO2002022527A2 (en) 2000-09-11 2001-09-11 Design and production of mutant 2,5-diketo-d-gluconic acid reductase enzymes with altered cofactor dependency

Publications (1)

Publication Number Publication Date
AU2001289000A1 true AU2001289000A1 (en) 2002-03-26

Family

ID=24642087

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001289000A Abandoned AU2001289000A1 (en) 2000-09-11 2001-09-11 Design and production of mutant 2,5-diketo-d-gluconic acid reductase enzymes with altered cofactor dependency

Country Status (3)

Country Link
US (1) US6423518B1 (en)
AU (1) AU2001289000A1 (en)
WO (1) WO2002022527A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6423518B1 (en) * 2000-09-11 2002-07-23 Rutgers, The State University Design and production of mutant 2,5-diketo-D-gluconic acid reductase enzymes with altered cofactor dependency
US7071307B2 (en) 2001-05-04 2006-07-04 Syngenta Participations Ag Nucleic acids and proteins with thioredoxin reductase activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5008193A (en) 1984-06-14 1991-04-16 Genentech, Inc. Ascorbic acid intermediates and process enzymes
US5376544A (en) 1992-09-08 1994-12-27 Rutgers The State University Of New Jersey Enzymes for the production of 2-keto-L-gulonic acid
US5795761A (en) 1996-01-11 1998-08-18 Rutgers, The State University Of New Jersey Mutants of 2,5-diketo-D-gluconic acid (2,5-DKG) reductase A
US6423518B1 (en) * 2000-09-11 2002-07-23 Rutgers, The State University Design and production of mutant 2,5-diketo-D-gluconic acid reductase enzymes with altered cofactor dependency

Also Published As

Publication number Publication date
WO2002022527A2 (en) 2002-03-21
US6423518B1 (en) 2002-07-23
WO2002022527A3 (en) 2003-08-28

Similar Documents

Publication Publication Date Title
AU2001278415A1 (en) Alpha-amylase mutants with altered stability
EP0796914A3 (en) Alcohol dehydrogenase and its use in the enzymatic production of chiral hydroxy-compounds
AU2002337743A1 (en) Method for formulating a glucose oxidase enzyme with a desired property or properties and a glucose oxidase enzyme with the desired property
AU2003248516A1 (en) New mutant strains of pseudomonas fluorescens and variants thereof, methods for their production, and uses thereof in alginate production
AU2001258229A1 (en) Alpha-amylase variants with altered 1,6-activity
AU6255796A (en) Mutant alpha-amylase
AU2001247788A1 (en) 32142, 21481, 25964, 21686, novel human dehydrogenase molecules and uses therefor
AU4178800A (en) Hydantoinase variants with improved properties and their use for the production of amino acids
WO2001014566A3 (en) Enzymatic synthesis of deoxyribonucleosides
AU2002219664A1 (en) Microorganism Producing L-Lysine And Processes For Producing L-Lysine Using The Same
AU2001289000A1 (en) Design and production of mutant 2,5-diketo-d-gluconic acid reductase enzymes with altered cofactor dependency
AU2003235506A1 (en) Targeted enzymes and methods of making and using targeted enzymes.
AU5721898A (en) Subunits of nadh dehydrogenase
EP1443104A4 (en) Microorganism and production of carotinoid compounds thereby
PT1482779E (en) Heat stable mutants of starch biosynthesis enzymes
AU2002359790A1 (en) Regulation of nad(p)h oxidase growth and transcription in melanoma cells
WO2000070057A3 (en) Mutant 1,3-propanediol dehydrogenase
AU2002305047A1 (en) Heat stable mutants of starch biosynthesis enzymes
AU3331300A (en) Enzyme capable of hydrolyzing plaque, microorganism producing thesame, and a composition comprising the same
IL154073A0 (en) Pyruvate: nadp+ oxidoreductase and uses thereof
AU6803800A (en) Dim mutants of mycobacteria and uses thereof
AU2001251122A1 (en) Tyr393 and tyr398 mutants of monoamine oxidase b
WO2003076640A3 (en) A process for the preparation of cephalosporan acid derivatives from cephalosporin c
AU1720501A (en) Methods of producing novel enzymes
AU2001273452A1 (en) 47885, a novel human ubiquitin-activating enzyme and uses therefor