AU2001286730A1 - An iap binding peptide or polypeptide and methods of using the same - Google Patents

An iap binding peptide or polypeptide and methods of using the same

Info

Publication number
AU2001286730A1
AU2001286730A1 AU2001286730A AU8673001A AU2001286730A1 AU 2001286730 A1 AU2001286730 A1 AU 2001286730A1 AU 2001286730 A AU2001286730 A AU 2001286730A AU 8673001 A AU8673001 A AU 8673001A AU 2001286730 A1 AU2001286730 A1 AU 2001286730A1
Authority
AU
Australia
Prior art keywords
polypeptide
methods
same
binding peptide
iap binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001286730A
Inventor
Emad S. Alnemri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thomas Jefferson University
Original Assignee
Thomas Jefferson University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomas Jefferson University filed Critical Thomas Jefferson University
Publication of AU2001286730A1 publication Critical patent/AU2001286730A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2001286730A 2000-08-24 2001-08-24 An iap binding peptide or polypeptide and methods of using the same Abandoned AU2001286730A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22773500P 2000-08-24 2000-08-24
US60/227,735 2000-08-24
PCT/US2001/026492 WO2002016418A2 (en) 2000-08-24 2001-08-24 An iap binding peptide or polypeptide and methods of using the same

Publications (1)

Publication Number Publication Date
AU2001286730A1 true AU2001286730A1 (en) 2002-03-04

Family

ID=22854247

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001286730A Abandoned AU2001286730A1 (en) 2000-08-24 2001-08-24 An iap binding peptide or polypeptide and methods of using the same

Country Status (5)

Country Link
US (1) US20020132786A1 (en)
EP (1) EP1315811A2 (en)
AU (1) AU2001286730A1 (en)
CA (1) CA2420534A1 (en)
WO (1) WO2002016418A2 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002026775A2 (en) * 2000-09-29 2002-04-04 Trustees Of Princeton University Compositions and methods for regulating apoptosis
US6992063B2 (en) * 2000-09-29 2006-01-31 The Trustees Of Princeton University Compositions and method for regulating apoptosis
WO2002030959A2 (en) * 2000-10-13 2002-04-18 Abbott Laboratories Peptides derived from smac (diablo) and methods of use therefor
JP2004531731A (en) * 2001-05-31 2004-10-14 ザ トラスティーズ オブ プリンストン ユニバーシテイ Assays for identifying IAP binding peptides and compounds that bind to IAP
EP1354953A1 (en) * 2002-04-17 2003-10-22 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Smac-peptides as therapeutics against cancer and autoimmune diseases
EP1354952A1 (en) * 2002-04-17 2003-10-22 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Smac-peptides as therapeutics against cancer and autoimmune diseases
EP1495124A2 (en) * 2002-04-17 2005-01-12 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Smac-peptides as therapeutics against cancer and autoimmune diseases
DE60334247D1 (en) 2002-11-27 2010-10-28 Irm Llc METHOD AND COMPOSITIONS FOR APOPTOSE INDUCTION IN CANCER CELLS
WO2004066958A2 (en) * 2003-01-30 2004-08-12 The Trustees Of Princeton University Caspase-9:bir3 domain of xiap complexes and methods of use
US20080199439A1 (en) * 2003-02-12 2008-08-21 Mclendon George L IAP-binding cargo molecules and peptidomimetics for use in diagnostic and therapeutic methods
JP4674231B2 (en) 2004-03-01 2011-04-20 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム Dimer small molecule apoptosis enhancer
JP5122275B2 (en) 2004-03-23 2013-01-16 ジェネンテック， インコーポレイテッド Azabicyclo-octane inhibitors of IAP
WO2006014361A1 (en) 2004-07-02 2006-02-09 Genentech, Inc. Inhibitors of iap
EP1773766B1 (en) 2004-07-15 2014-04-02 Tetralogic Pharmaceuticals Corporation Iap binding compounds
ES2349110T5 (en) 2004-12-20 2013-11-27 Genentech, Inc. IAP inhibitors derived from pyrrolidine
US7517906B2 (en) 2005-02-25 2009-04-14 Tetralogic Pharmaceuticals Corporation Dimeric IAP inhibitors
US20100256046A1 (en) * 2009-04-03 2010-10-07 Tetralogic Pharmaceuticals Corporation Treatment of proliferative disorders
AU2006279929A1 (en) * 2005-08-09 2007-02-22 Tetralogic Pharmaceuticals Corporation Treatment of proliferative disorders
CN101374829A (en) 2005-12-19 2009-02-25 健泰科生物技术公司 Inhibitors of IAP
WO2008014236A1 (en) * 2006-07-24 2008-01-31 Tetralogic Pharmaceuticals Corporation Dimeric iap inhibitors
WO2008014240A2 (en) * 2006-07-24 2008-01-31 Tetralogic Pharmaceuticals Corporation Dimeric iap inhibitors
JP5452223B2 (en) * 2006-07-24 2014-03-26 テトラロジック ファーマシューティカルズ コーポレーション IAP inhibitor
KR20090041391A (en) * 2006-07-24 2009-04-28 테트랄로직 파마슈티칼스 Dimeric iap antagonists
KR20090094461A (en) 2006-12-19 2009-09-07 제넨테크, 인크. Imidazopyridine inhibitors of iap
TWI432212B (en) 2007-04-30 2014-04-01 Genentech Inc Inhibitors of iap
EP2116602A1 (en) 2008-05-07 2009-11-11 Institut Gustave Roussy Combination products for treating cancer
EP2318395A4 (en) 2008-08-02 2011-10-26 Genentech Inc Inhibitors of iap
US8283372B2 (en) * 2009-07-02 2012-10-09 Tetralogic Pharmaceuticals Corp. 2-(1H-indol-3-ylmethyl)-pyrrolidine dimer as a SMAC mimetic
CN110636853B (en) * 2017-05-19 2024-10-18 佐治亚州立大学研究基金会公司 Recombinant oncolytic viruses

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3395900A (en) * 1999-03-12 2000-10-04 Human Genome Sciences, Inc. Human lung cancer associated gene sequences and polypeptides
US6110691A (en) * 2000-01-06 2000-08-29 Board Of Regents, The University Of Texas System Activators of caspases
US6608026B1 (en) * 2000-08-23 2003-08-19 Board Of Regents, The University Of Texas System Apoptotic compounds

Also Published As

Publication number Publication date
CA2420534A1 (en) 2002-02-28
EP1315811A2 (en) 2003-06-04
WO2002016418A3 (en) 2003-02-06
US20020132786A1 (en) 2002-09-19
WO2002016418A2 (en) 2002-02-28

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