AU2001286259A1 - Tricyclic indole compounds having affinity for serotonin receptor - Google Patents

Tricyclic indole compounds having affinity for serotonin receptor

Info

Publication number
AU2001286259A1
AU2001286259A1 AU2001286259A AU8625901A AU2001286259A1 AU 2001286259 A1 AU2001286259 A1 AU 2001286259A1 AU 2001286259 A AU2001286259 A AU 2001286259A AU 8625901 A AU8625901 A AU 8625901A AU 2001286259 A1 AU2001286259 A1 AU 2001286259A1
Authority
AU
Australia
Prior art keywords
affinity
serotonin receptor
indole compounds
tricyclic indole
tricyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001286259A
Inventor
Makoto Adachi
Yoshikazu Fukui
Takashi Sasatani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of AU2001286259A1 publication Critical patent/AU2001286259A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
AU2001286259A 2000-09-22 2001-09-17 Tricyclic indole compounds having affinity for serotonin receptor Abandoned AU2001286259A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000287809 2000-09-22
JP2000-287809 2000-09-22
PCT/JP2001/008049 WO2002024641A1 (en) 2000-09-22 2001-09-17 Tricyclic indole compounds having affinity for serotonin receptor

Publications (1)

Publication Number Publication Date
AU2001286259A1 true AU2001286259A1 (en) 2002-04-02

Family

ID=18771501

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001286259A Abandoned AU2001286259A1 (en) 2000-09-22 2001-09-17 Tricyclic indole compounds having affinity for serotonin receptor

Country Status (6)

Country Link
US (2) US6858640B2 (en)
EP (1) EP1325909A4 (en)
JP (1) JPWO2002024641A1 (en)
AU (1) AU2001286259A1 (en)
TW (1) TWI227236B (en)
WO (1) WO2002024641A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002024641A1 (en) * 2000-09-22 2002-03-28 Shionogi & Co., Ltd. Tricyclic indole compounds having affinity for serotonin receptor
CA2532403A1 (en) 2003-07-17 2005-02-03 James Arnold Ppar active compounds
CN114075212B (en) * 2020-08-14 2023-05-12 江苏恒瑞医药股份有限公司 Fused tricyclic derivatives, preparation method thereof and application thereof in medicines
WO2023173196A1 (en) 2022-03-18 2023-09-21 Enveric Biosciences Canada Inc. C4-carboxylic acid-substituted tryptamine derivatives and methods of using

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9407637D0 (en) 1994-04-18 1994-06-08 Erba Carlo Spa Serotoninergic abeo-ergoline derivatives
JPH11503757A (en) 1995-04-18 1999-03-30 イーライ・リリー・アンド・カンパニー Use of ergoline compounds that produce physiological and pathological functions at 5-HT (7) receptors
WO2000059909A1 (en) * 1999-03-30 2000-10-12 Shionogi & Co., Ltd. Heterocyclic compounds having affinities for serotonin receptors
WO2002024641A1 (en) * 2000-09-22 2002-03-28 Shionogi & Co., Ltd. Tricyclic indole compounds having affinity for serotonin receptor

Also Published As

Publication number Publication date
US20050043387A1 (en) 2005-02-24
WO2002024641A1 (en) 2002-03-28
US6858640B2 (en) 2005-02-22
EP1325909A1 (en) 2003-07-09
JPWO2002024641A1 (en) 2004-01-29
TWI227236B (en) 2005-02-01
US20030236295A1 (en) 2003-12-25
EP1325909A4 (en) 2004-12-08

Similar Documents

Publication Publication Date Title
HK1045512B (en) Tetracyclic azepinoindole compounds as 5-ht receptor ligands
HK1068610A1 (en) New indole derivatives with 5-ht6 receptor affinity
AU4664696A (en) Indole derivatives as 5-ht receptor antagonist
AU5633300A (en) Indole compounds
AU3840000A (en) Tricyclic compounds
AU2399401A (en) Spiro compounds useful as opioid delta receptor agonist
AU1948601A (en) Triazospiro compounds having nociceptin receptor affinity
AU2002336749A1 (en) Tricyclic indole derivatives as 5-ht ligands
AU3195600A (en) Tricyclic indole-2-carboxylic acid compound used as nmda receptor antagonist
AU4316301A (en) Novel 2,3,4,5-tetrahydro-1H-(1,4)diazepino(1,7a)indole compounds
AU2001259051A1 (en) Piperidyindoles as serotonin receptor ligands
AU2001295455A1 (en) Indoline derivatives as 5ht2c antagonists
AU3550697A (en) Aminocyclohexane derivatives as 5-ht receptor agonists
AU2001286259A1 (en) Tricyclic indole compounds having affinity for serotonin receptor
AU2002362041A1 (en) Tetracyclic heterocompounds as estrogen receptor modulators
AU2001252575A1 (en) Novel tricyclic compounds
AU1339301A (en) Novel indole compounds
AU1382901A (en) Novel triazaspirodecanones with high affinity for opioid receptor subtypes
AU1100300A (en) Piperidyloxadiazoles as dopamine receptor antagonists
PL344594A1 (en) N-benzodioxanylmethyl-1-piperidyl-methylamine compounds having affinity for 5-ht receptors
AU2713399A (en) 5-heteroaryl substituted indoles
AU5633800A (en) Indole compounds
AU2001252573A1 (en) Novel substituted tricyclic compounds
AU2943899A (en) Indole derivatives as 5-ht2a receptor antagonists
AU2230101A (en) Tricyclic compounds