AU2001285820A1 - Diagnostic and therapeutic methods based on the l1 adhesion molecule for ovarian and endometrial tumors - Google Patents

Diagnostic and therapeutic methods based on the l1 adhesion molecule for ovarian and endometrial tumors

Info

Publication number
AU2001285820A1
AU2001285820A1 AU2001285820A AU8582001A AU2001285820A1 AU 2001285820 A1 AU2001285820 A1 AU 2001285820A1 AU 2001285820 A AU2001285820 A AU 2001285820A AU 8582001 A AU8582001 A AU 8582001A AU 2001285820 A1 AU2001285820 A1 AU 2001285820A1
Authority
AU
Australia
Prior art keywords
ovarian
diagnostic
adhesion molecule
methods based
therapeutic methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001285820A
Inventor
Peter Altevogt
Mina Fogel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deutsches Krebsforschungszentrum DKFZ
Mor Research Applications Ltd
Original Assignee
Deutsches Krebsforschungszentrum DKFZ
Mor Research Applications Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsches Krebsforschungszentrum DKFZ, Mor Research Applications Ltd filed Critical Deutsches Krebsforschungszentrum DKFZ
Publication of AU2001285820A1 publication Critical patent/AU2001285820A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57449—Specifically defined cancers of ovaries
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57442—Specifically defined cancers of the uterus and endometrial
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705

Abstract

A method is described for the diagnosis of an ovarian or endometrial tumor or for a prognosis, characterized in that the L1 level is determined in a patient sample, preferably via an anti L1 antibody, the presence of L1 being an indication of the presence of an ovarian or endometrial tumor or a predisposition for such a tumor.
AU2001285820A 2000-07-10 2001-07-10 Diagnostic and therapeutic methods based on the l1 adhesion molecule for ovarian and endometrial tumors Abandoned AU2001285820A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00114788A EP1172654B1 (en) 2000-07-10 2000-07-10 Diagnostic method based on the detection of the L1 adhesion molecule for ovarian and endometrial tumors
EP00114788.3 2000-07-10
PCT/EP2001/007924 WO2002004952A2 (en) 2000-07-10 2001-07-10 Diagnostic and therapeutic methods based on the l1 adhesion molecule for ovarian and endometrial tumors

Publications (1)

Publication Number Publication Date
AU2001285820A1 true AU2001285820A1 (en) 2002-01-21

Family

ID=8169210

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001285820A Abandoned AU2001285820A1 (en) 2000-07-10 2001-07-10 Diagnostic and therapeutic methods based on the l1 adhesion molecule for ovarian and endometrial tumors

Country Status (10)

Country Link
US (2) US7618785B2 (en)
EP (2) EP1172654B1 (en)
JP (1) JP5165827B2 (en)
CN (1) CN1479871A (en)
AT (1) ATE377192T1 (en)
AU (1) AU2001285820A1 (en)
CA (1) CA2415364C (en)
DE (1) DE60036935T2 (en)
ES (1) ES2296586T3 (en)
WO (1) WO2002004952A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE377192T1 (en) * 2000-07-10 2007-11-15 Deutsches Krebsforsch DIAGNOSTIC METHOD FOR OVARIAN AND ENDOMETRIAL TUMORS BASED ON DETECTION OF THE L1 ADHESION MOLECULE
US6852874B2 (en) 2000-10-02 2005-02-08 The Scripps Research Institute Second cycle asymmetric dihydroxylation reaction
EP1623995A1 (en) * 2004-08-06 2006-02-08 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Inhibitors of L1 and ADAM10 for the treatment of carcinomas
WO2007114550A1 (en) * 2006-04-03 2007-10-11 Korea Research Institute Of Bioscience And Biotechnology A novel monoclonal antibody specific to the l1cam, a hybridoma producing the same and a method producing the same
CN101528258A (en) 2006-08-23 2009-09-09 韩国生命工学研究院 A pharmaceutical composition for treating lung cancer, a method for inhibiting growth or invasion of lung cancer and a method for treating lung cancer
CA2958672A1 (en) 2007-06-15 2008-12-18 Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts Treatment of tumors using specific anti-l1 antibody
AU2008201871A1 (en) * 2008-04-16 2009-11-26 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts Inhibition of angiogenesis and tumor metastasis
KR20100060351A (en) 2008-11-27 2010-06-07 한국생명공학연구원 A composition for treating l1cam-expressing cancer comprising an inhibitor of activity or expression of l1cam and anticancer agent
KR101504039B1 (en) * 2012-11-16 2015-03-19 강원대학교산학협력단 Antibody specifically binding to L1CAM in humans and mice, and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4939240A (en) * 1983-03-04 1990-07-03 Health Research, Inc. Monoclonal antibodies to human breast carcinoma cells and their use in diagnosis and therapy
WO1999064626A2 (en) 1998-06-06 1999-12-16 Genostic Pharma Limited Probes used for genetic profiling
ATE377192T1 (en) 2000-07-10 2007-11-15 Deutsches Krebsforsch DIAGNOSTIC METHOD FOR OVARIAN AND ENDOMETRIAL TUMORS BASED ON DETECTION OF THE L1 ADHESION MOLECULE
US20020115065A1 (en) * 2000-08-28 2002-08-22 Ton Logtenberg Differentially expressed epitopes and uses thereof
WO2002069198A2 (en) * 2001-02-21 2002-09-06 The Board Of Regents Of The University Of Oklahoma Hla ligand database utilizing predictive algorithms and methods of making and using same

Also Published As

Publication number Publication date
DE60036935D1 (en) 2007-12-13
WO2002004952A2 (en) 2002-01-17
ES2296586T3 (en) 2008-05-01
CA2415364A1 (en) 2002-01-17
US20080138331A1 (en) 2008-06-12
US20040259084A1 (en) 2004-12-23
EP1172654B1 (en) 2007-10-31
US7618785B2 (en) 2009-11-17
EP1386162A2 (en) 2004-02-04
EP1172654A1 (en) 2002-01-16
JP2004513074A (en) 2004-04-30
ATE377192T1 (en) 2007-11-15
DE60036935T2 (en) 2008-08-21
CN1479871A (en) 2004-03-03
US7670601B2 (en) 2010-03-02
CA2415364C (en) 2009-02-24
WO2002004952A3 (en) 2003-11-06
JP5165827B2 (en) 2013-03-21

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