AU2001284794A1 - Angiotensin converting enzyme homolog and uses therefor - Google Patents

Angiotensin converting enzyme homolog and uses therefor

Info

Publication number
AU2001284794A1
AU2001284794A1 AU2001284794A AU8479401A AU2001284794A1 AU 2001284794 A1 AU2001284794 A1 AU 2001284794A1 AU 2001284794 A AU2001284794 A AU 2001284794A AU 8479401 A AU8479401 A AU 8479401A AU 2001284794 A1 AU2001284794 A1 AU 2001284794A1
Authority
AU
Australia
Prior art keywords
converting enzyme
angiotensin converting
uses therefor
enzyme homolog
homolog
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001284794A
Inventor
Susan Acton
Frank Y. Hsieh
Keith E. Robison
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Millennium Pharmaceuticals Inc
Original Assignee
Millennium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/635,501 external-priority patent/US6884771B1/en
Application filed by Millennium Pharmaceuticals Inc filed Critical Millennium Pharmaceuticals Inc
Publication of AU2001284794A1 publication Critical patent/AU2001284794A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/15—Peptidyl-dipeptidases (3.4.15)
    • C12Y304/15001—Peptidyl-dipeptidase A (3.4.15.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2001284794A 2000-08-09 2001-08-09 Angiotensin converting enzyme homolog and uses therefor Abandoned AU2001284794A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/635,501 US6884771B1 (en) 1997-12-11 2000-08-09 Angiotensin converting enzyme homolog and uses therefor
US09/635,501 2000-08-09
PCT/US2001/025059 WO2002012471A2 (en) 2000-08-09 2001-08-09 Angiotensin converting enzyme homolog and uses therefor

Publications (1)

Publication Number Publication Date
AU2001284794A1 true AU2001284794A1 (en) 2002-02-18

Family

ID=24548043

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001284794A Abandoned AU2001284794A1 (en) 2000-08-09 2001-08-09 Angiotensin converting enzyme homolog and uses therefor

Country Status (2)

Country Link
AU (1) AU2001284794A1 (en)
WO (1) WO2002012471A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6900033B2 (en) 2001-06-04 2005-05-31 Human Genome Sciences, Inc. Methods and compositions for modulating ACE-2 activity
EP1401864A1 (en) 2001-06-04 2004-03-31 Human Genome Sciences Methods and compositions for modulating ace-2 activity
JP4598518B2 (en) * 2002-06-19 2010-12-15 ユニバーシティー ヘルス ネットワーク ACE2 activation for the treatment of heart, lung and kidney disease and hypertension
CA2504205A1 (en) * 2002-10-29 2004-05-13 Gen Kondoh Angiotensin-converting enzyme containing medecine
EP1723962A1 (en) 2005-05-19 2006-11-22 IMBA-Institut für Molekulare Biotechnologie GmbH Use of inhibitors of the renin-angiotensin system for the treatment of lung injuries
US20090186014A1 (en) * 2007-10-10 2009-07-23 Ore Pharmaceuticals Inc. Method for treatment of pancreatitis
US20100035848A1 (en) * 2008-03-10 2010-02-11 Stephen Richard Donahue Therapy for disorders of the proximal digestive tract
US20110229922A1 (en) * 2008-12-02 2011-09-22 Jeremy Beauchamp Screening assays for the identification of bace2 inhibitors
US20210238229A1 (en) * 2018-06-14 2021-08-05 University College Cork - National University Of Ireland, Cork Peptide for disease treatment
US20230174611A1 (en) * 2020-04-24 2023-06-08 Administrators Of The Tulane Educational Fund Compositions and methods for preventing or reducing the effects of infections by coronaviruses that bind the extracellular domain of the ace2 receptor
WO2021236957A2 (en) * 2020-05-20 2021-11-25 Emmune, Inc. Ace2 muteins and methods of using the same
CA3216329A1 (en) * 2021-04-20 2022-10-27 The Council Of The Queensland Institute Of Medical Research Novel compositions and methods for treating coronavirus infections
EP4147702A1 (en) 2021-09-13 2023-03-15 Medizinische Universität Graz Novel combination of heparin and ace2 decoys for the treatment of covid-19

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6989363B1 (en) * 1997-12-11 2006-01-24 Millennium Pharmaceuticals, Inc. Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therefor
DE69832053T2 (en) * 1998-05-13 2006-07-20 Smithkline Beecham P.L.C., Brentford Human polypeptides and polynucleotides with homology to the testis-specific angiotensin converting enzyme
JP2000037185A (en) * 1998-07-23 2000-02-08 Ajinomoto Co Inc Production of freeze resistant yeast

Also Published As

Publication number Publication date
WO2002012471A3 (en) 2003-01-03
WO2002012471A2 (en) 2002-02-14

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