AU2001283031A1 - Apparatus for generating a temperature gradient and methods for using the gradient to characterize molecular interactions - Google Patents

Apparatus for generating a temperature gradient and methods for using the gradient to characterize molecular interactions

Info

Publication number
AU2001283031A1
AU2001283031A1 AU2001283031A AU8303101A AU2001283031A1 AU 2001283031 A1 AU2001283031 A1 AU 2001283031A1 AU 2001283031 A AU2001283031 A AU 2001283031A AU 8303101 A AU8303101 A AU 8303101A AU 2001283031 A1 AU2001283031 A1 AU 2001283031A1
Authority
AU
Australia
Prior art keywords
gradient
generating
methods
molecular interactions
characterize molecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001283031A
Inventor
Martin Blumenfeld
Gregory T. Cibuzar
Mark Fisher
Brian G. Van Ness
Fred Williamson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Minnesota
Original Assignee
University of Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Minnesota filed Critical University of Minnesota
Publication of AU2001283031A1 publication Critical patent/AU2001283031A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/54—Heating or cooling apparatus; Heat insulating devices using spatial temperature gradients
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12—Specific details about manufacturing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
AU2001283031A 2000-08-01 2001-07-30 Apparatus for generating a temperature gradient and methods for using the gradient to characterize molecular interactions Abandoned AU2001283031A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/630,172 US6544477B1 (en) 2000-08-01 2000-08-01 Apparatus for generating a temperature gradient
US09630172 2000-08-01
PCT/US2001/023831 WO2002009868A2 (en) 2000-08-01 2001-07-30 Apparatus for generating a temperature gradient and methods for using the gradient to characterize molecular interactions

Publications (1)

Publication Number Publication Date
AU2001283031A1 true AU2001283031A1 (en) 2002-02-13

Family

ID=24526085

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001283031A Abandoned AU2001283031A1 (en) 2000-08-01 2001-07-30 Apparatus for generating a temperature gradient and methods for using the gradient to characterize molecular interactions

Country Status (6)

Country Link
US (3) US6544477B1 (en)
EP (1) EP1307293A2 (en)
JP (1) JP2004505255A (en)
AU (1) AU2001283031A1 (en)
CA (1) CA2417889A1 (en)
WO (1) WO2002009868A2 (en)

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JP2002355038A (en) * 2001-03-29 2002-12-10 Japan Science & Technology Corp Gene analysis method and analyzer therefor
AU2002312411A1 (en) * 2001-06-07 2002-12-16 Proligo Llc Microcalorimetric detection of analytes and binding events
US7244611B2 (en) * 2001-10-23 2007-07-17 Nikon Research Corporation Of America Methods and devices for hybridization and binding assays using thermophoresis
US20060134683A1 (en) * 2001-10-23 2006-06-22 Michael Sogard Methods and devices for hybridization and binding assays using thermophoresis
AU2002359329A1 (en) * 2001-10-30 2003-05-12 The Texas A And M University System Method and apparatus for temperature gradient microfluidics
US7232547B2 (en) * 2002-03-22 2007-06-19 Marshfield Clinic Apparatus and method for testing and continuously reading low-volume samples
US7452712B2 (en) 2002-07-30 2008-11-18 Applied Biosystems Inc. Sample block apparatus and method of maintaining a microcard on a sample block
WO2005058501A1 (en) * 2002-09-09 2005-06-30 Bjs Company Ltd Heating samples in specimen carriers
US8398632B1 (en) * 2003-06-10 2013-03-19 Medtronic Cryocath Lp Surgical clamp having treatment elements
US7044946B2 (en) 2003-06-10 2006-05-16 Cryocath Technologies Inc. Surgical clamp having treatment elements
US7819860B2 (en) 2003-06-10 2010-10-26 Medtronic Cryocath Lp Surgical clamp having trasmurality assessment capabilities
US7570443B2 (en) 2003-09-19 2009-08-04 Applied Biosystems, Llc Optical camera alignment
US20050237528A1 (en) * 2003-09-19 2005-10-27 Oldham Mark F Transparent heater for thermocycling
EP1695110A2 (en) * 2003-11-21 2006-08-30 Koninklijke Philips Electronics N.V. Ultrasound imaging system and method having adaptive selection of image frame rate and/or number of echo samples averaged
JP4179169B2 (en) * 2004-01-08 2008-11-12 カシオ計算機株式会社 Analysis equipment
CA2564838A1 (en) * 2004-04-28 2005-11-10 Eisai R&D Management Co., Ltd. Hybridization method
JP4667769B2 (en) * 2004-06-11 2011-04-13 信越ポリマー株式会社 Substrate storage container
US7585663B2 (en) * 2004-08-26 2009-09-08 Applied Biosystems, Llc Thermal device, system, and method, for fluid processing device
US20100190265A1 (en) * 2005-12-02 2010-07-29 Technical University Of Denmark Fluidics device for assay
US20090099045A1 (en) * 2007-10-10 2009-04-16 Biotex, Inc. Methods and devices for molecular association and imaging
WO2012033914A1 (en) * 2010-09-09 2012-03-15 Battelle Memorial Institute Heating a short section of tape or wire to a controlled temperature
DK3472351T3 (en) 2016-06-15 2020-11-09 Univ Muenchen Ludwig Maximilians Single molecule detection or quantification using DNA nanotechnology

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US4422129A (en) * 1982-08-19 1983-12-20 General Electric Company Humidity sensor
DE3504498A1 (en) * 1985-02-09 1986-08-14 Drägerwerk AG, 2400 Lübeck GAS SENSOR WITH SEVERAL SENSOR ELEMENTS
DE3622591C2 (en) 1986-07-04 1998-11-19 Qiagen Gmbh Method and device for producing a controllable and reproducible temperature gradient and its use
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Also Published As

Publication number Publication date
US6610470B2 (en) 2003-08-26
WO2002009868A2 (en) 2002-02-07
US6544477B1 (en) 2003-04-08
US20020015996A1 (en) 2002-02-07
US6733729B2 (en) 2004-05-11
EP1307293A2 (en) 2003-05-07
US20020015995A1 (en) 2002-02-07
CA2417889A1 (en) 2002-02-07
WO2002009868A3 (en) 2002-06-27
JP2004505255A (en) 2004-02-19

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