AU2001280764A1 - Drug delivery system for enhanced bioavailability of hydrophobic active ingredients - Google Patents
Drug delivery system for enhanced bioavailability of hydrophobic active ingredientsInfo
- Publication number
- AU2001280764A1 AU2001280764A1 AU2001280764A AU8076401A AU2001280764A1 AU 2001280764 A1 AU2001280764 A1 AU 2001280764A1 AU 2001280764 A AU2001280764 A AU 2001280764A AU 8076401 A AU8076401 A AU 8076401A AU 2001280764 A1 AU2001280764 A1 AU 2001280764A1
- Authority
- AU
- Australia
- Prior art keywords
- delivery system
- drug delivery
- active ingredients
- hydrophobic active
- enhanced bioavailability
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09635234 | 2000-08-09 | ||
US09/635,234 US6531158B1 (en) | 2000-08-09 | 2000-08-09 | Drug delivery system for enhanced bioavailability of hydrophobic active ingredients |
PCT/US2001/023401 WO2002011699A1 (en) | 2000-08-09 | 2001-07-26 | Drug delivery system for enhanced bioavailability of hydrophobic active ingredients |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001280764A1 true AU2001280764A1 (en) | 2002-02-18 |
Family
ID=24546994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001280764A Abandoned AU2001280764A1 (en) | 2000-08-09 | 2001-07-26 | Drug delivery system for enhanced bioavailability of hydrophobic active ingredients |
Country Status (4)
Country | Link |
---|---|
US (2) | US6531158B1 (en) |
AU (1) | AU2001280764A1 (en) |
TW (1) | TWI285116B (en) |
WO (1) | WO2002011699A1 (en) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL130602A0 (en) | 1999-06-22 | 2000-06-01 | Dexcel Ltd | Stable benzimidazole formulation |
JPWO2002069957A1 (en) * | 2001-03-01 | 2004-07-02 | グレラン製薬株式会社 | Fenofibrate-containing composition |
JP2005531521A (en) * | 2002-03-26 | 2005-10-20 | テバ ファーマシューティカル インダストリーズ リミティド | Drag fine particles |
WO2004028506A1 (en) * | 2002-09-24 | 2004-04-08 | Ranbaxy Laboratories Limited | Oral pharmaceutical compositions of fenofibrate having high bioavailability |
CN100473378C (en) * | 2002-12-17 | 2009-04-01 | 阿伯特有限及两合公司 | Formulation comprising fenofibric acid, a physiologically acceptable salt or derivative thereof |
EP1829541A1 (en) * | 2002-12-17 | 2007-09-05 | Abbott GmbH & Co. KG | Formulation comprising fenofibric acid or a physiologically acceptable salt thereof |
BE1015641A4 (en) * | 2003-05-26 | 2005-07-05 | Mariani Jean Paul | Micronization 70. |
EP1559419A1 (en) * | 2004-01-23 | 2005-08-03 | Fournier Laboratories Ireland Limited | Pharmaceutical formulations comprising metformin and a fibrate, and processes for their obtention |
KR101499822B1 (en) | 2006-01-20 | 2015-03-06 | 오클루스 이노바티브 사이언시즈 인코포레이티드 | Methods of treating or preventing sinusitis with oxidative reductive potential water solution |
CA2644905A1 (en) * | 2006-03-06 | 2007-09-13 | Teva Pharmaceutical Industries Ltd. | Ezetimibe compositions |
EP2029110B1 (en) | 2006-06-06 | 2011-08-31 | Tibotec Pharmaceuticals | Process for preparing spray dried formulations of tmc125 |
KR20090045205A (en) * | 2006-06-26 | 2009-05-07 | 뮤추얼 파마슈티컬 컴퍼니 아이엔씨. | Active agent formulations, methods of making, and methods of use |
JP2010513325A (en) * | 2006-12-21 | 2010-04-30 | アルファファーム ピーティーワイ リミテッド | Pharmaceutical composition |
WO2008104846A2 (en) * | 2007-02-26 | 2008-09-04 | Wockhardt Research Centre | Pharmaceutical compositions of fenofibrate |
US9180110B2 (en) | 2007-02-26 | 2015-11-10 | Wockhardt Ltd. | Pharmaceutical compositions of fenofibrate |
WO2009042114A2 (en) | 2007-09-21 | 2009-04-02 | The Johns Hopkins University | Phenazine derivatives and uses thereof |
BRPI0917444A2 (en) | 2008-08-15 | 2015-12-01 | Depomed Inc | gastric retention pharmaceutical compositions for the treatment and prevention of snc diseases |
US20100159010A1 (en) * | 2008-12-24 | 2010-06-24 | Mutual Pharmaceutical Company, Inc. | Active Agent Formulations, Methods of Making, and Methods of Use |
US20100166857A1 (en) * | 2008-12-30 | 2010-07-01 | Dong Yan | Pharmaceutical dosage forms and methods of manufacturing same |
FR2943539B1 (en) * | 2009-03-31 | 2011-07-22 | Ethypharm Sa | PHARMACEUTICAL COMPOSITION COMPRISING A IMMUNOSUPPRESSIVE MACROLIDE OF THE LIMUS FAMILY. |
CN102480972B (en) | 2009-06-15 | 2014-12-10 | 奥古露丝创新科学公司 | Solution containing hypochlorous acid and methods of using same |
KR101202994B1 (en) * | 2010-04-12 | 2012-11-21 | 한미사이언스 주식회사 | Oral pharmaceutical composition comprising fenofibric acid and an alkalifying agent |
WO2014091318A1 (en) | 2012-12-11 | 2014-06-19 | Lupin Atlantis Holdings, S.A. | Reduced dose pharmaceutical compositions of fenofibrate |
WO2018187849A1 (en) * | 2017-04-13 | 2018-10-18 | Pharmako Biotechnologies Pty Limited | Cold-water-dispersible chemical delivery system |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3639637A (en) | 1968-04-23 | 1972-02-01 | Richardson Merrell Inc | Water dispersible diethylstilbestrol compositions |
US4013785A (en) | 1975-03-21 | 1977-03-22 | Bristol-Myers Company | Apap tablet containing fumed silica and process for manufacturing same |
GB1579818A (en) | 1977-06-07 | 1980-11-26 | Yamanouchi Pharma Co Ltd | Nifedipine-containing solid preparation composition |
US4153678A (en) * | 1978-07-17 | 1979-05-08 | American Cyanamid Company | Levamisole effervescent tablets |
US4344934A (en) * | 1978-11-20 | 1982-08-17 | American Home Products Corporation | Therapeutic compositions with enhanced bioavailability |
FR2494112B1 (en) | 1980-11-19 | 1986-01-10 | Laruelle Claude | |
DE3107933A1 (en) | 1981-03-02 | 1982-09-16 | Cassella Ag, 6000 Frankfurt | SUBSTITUTED 3-AMINO-SYDNONIMINE, METHOD FOR THE PRODUCTION AND USE THEREOF |
DE3247118A1 (en) | 1982-12-20 | 1984-06-20 | Cassella Ag, 6000 Frankfurt | NEW SUBSTITUTED 1,4-DIHYDROPYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT |
FR2557459B1 (en) | 1984-01-02 | 1986-05-30 | Lhd Lab Hygiene Dietetique | POLYCAPROLACTONE-BASED INERT MATRIX FOR ORAL ADMINISTRATION OF A MEDICAMENT, AND METHOD FOR PREPARING THE GALENIC FORM COMPRISING THE SAME |
US4721709A (en) | 1984-07-26 | 1988-01-26 | Pyare Seth | Novel pharmaceutical compositions containing hydrophobic practically water-insoluble drugs adsorbed on pharmaceutical excipients as carrier; process for their preparation and the use of said compositions |
EP0179583A1 (en) | 1984-10-04 | 1986-04-30 | Merck & Co. Inc. | A system for enhancing the water dissolution rate and solubility of poorly soluble drugs |
EP0232254A1 (en) | 1985-07-24 | 1987-08-19 | SETH, Pyare | Oxazepam containing pharmaceutical composition |
US4716033A (en) | 1986-03-27 | 1987-12-29 | Warner-Lambert Company | Medicament adsorbates with surfactant and their preparation |
FR2602423B1 (en) | 1986-08-08 | 1989-05-05 | Ethypharm Sa | PROCESS FOR THE PREPARATION OF A FENOFIBRATE-BASED MEDICINAL PRODUCT, OBTAINED BY THIS PROCESS |
US4859703A (en) | 1987-06-15 | 1989-08-22 | Warner-Lambert Company | Lipid regulating compositions |
FR2627696B1 (en) * | 1988-02-26 | 1991-09-13 | Fournier Innovation Synergie | NEW GALENIC FORM OF FENOFIBRATE |
SE8803935L (en) * | 1988-10-31 | 1990-05-01 | Kabivitrum Ab | LAEKEMEDELSKOMPOSITION |
US5228400A (en) * | 1991-07-30 | 1993-07-20 | Luke William J | Planting tool |
TW355683B (en) * | 1994-02-17 | 1999-04-11 | Janssen Pharmaceutica Nv | Composition containing micronized nebivolol |
US5948438A (en) | 1995-01-09 | 1999-09-07 | Edward Mendell Co., Inc. | Pharmaceutical formulations having improved disintegration and/or absorptivity |
US5545628A (en) * | 1995-01-10 | 1996-08-13 | Galephar P.R. Inc. | Pharmaceutical composition containing fenofibrate |
FR2737121B1 (en) | 1995-07-27 | 1997-10-03 | Cl Pharma | NEW GALENIC FORMULATIONS OF FENOFIBRATE AND THEIR APPLICATIONS |
US5769934A (en) | 1997-01-15 | 1998-06-23 | Fmc Corporation | Method for producing microcrystalline cellulose |
FR2758459B1 (en) * | 1997-01-17 | 1999-05-07 | Pharma Pass | FENOFIBRATE PHARMACEUTICAL COMPOSITION HAVING HIGH BIODAVAILABILITY AND PROCESS FOR PREPARING THE SAME |
CA2214895C (en) * | 1997-09-19 | 1999-04-20 | Bernard Charles Sherman | Improved pharmaceutical composition comprising fenofibrate |
FR2774591B1 (en) * | 1998-02-12 | 2000-05-05 | Lipha | PHARMACEUTICAL COMPOSITION COMPRISING THE ASSOCIATION OF METFORMIN AND FIBRATE AND THE USE THEREOF FOR THE PREPARATION OF MEDICINES FOR REDUCING HYPERGLYCEMIA |
BR9908911A (en) * | 1998-03-19 | 2001-10-02 | Bristol Myers Squibb Co | Biphasic system and distribution process by controlled release of high solubility pharmaceutical substances |
US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
CA2270306C (en) * | 1999-04-27 | 2000-09-26 | Bernard Charles Sherman | Pharmaceutical compositions comprising co-micronized fenofibrate |
-
2000
- 2000-08-09 US US09/635,234 patent/US6531158B1/en not_active Expired - Fee Related
-
2001
- 2001-07-26 AU AU2001280764A patent/AU2001280764A1/en not_active Abandoned
- 2001-07-26 WO PCT/US2001/023401 patent/WO2002011699A1/en active Application Filing
- 2001-08-01 TW TW090118724A patent/TWI285116B/en not_active IP Right Cessation
-
2002
- 2002-11-21 US US10/300,808 patent/US20030138496A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2002011699A1 (en) | 2002-02-14 |
US6531158B1 (en) | 2003-03-11 |
TWI285116B (en) | 2007-08-11 |
US20030138496A1 (en) | 2003-07-24 |
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