AU2001279950A1 - Tetrahydropyran derivatives as nk-1 receptor antagonists - Google Patents
Tetrahydropyran derivatives as nk-1 receptor antagonistsInfo
- Publication number
- AU2001279950A1 AU2001279950A1 AU2001279950A AU7995001A AU2001279950A1 AU 2001279950 A1 AU2001279950 A1 AU 2001279950A1 AU 2001279950 A AU2001279950 A AU 2001279950A AU 7995001 A AU7995001 A AU 7995001A AU 2001279950 A1 AU2001279950 A1 AU 2001279950A1
- Authority
- AU
- Australia
- Prior art keywords
- receptor antagonists
- tetrahydropyran derivatives
- tetrahydropyran
- derivatives
- antagonists
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 102000002002 Neurokinin-1 Receptors Human genes 0.000 title 1
- 108010040718 Neurokinin-1 Receptors Proteins 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
- 150000003527 tetrahydropyrans Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0020721.7A GB0020721D0 (en) | 2000-08-22 | 2000-08-22 | Therapeutic agents |
GB0020721 | 2000-08-22 | ||
PCT/GB2001/003699 WO2002016344A1 (en) | 2000-08-22 | 2001-08-17 | Tetrahydropyran derivatives as nk-1 receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001279950A1 true AU2001279950A1 (en) | 2002-03-04 |
Family
ID=9898111
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001279950A Abandoned AU2001279950A1 (en) | 2000-08-22 | 2001-08-17 | Tetrahydropyran derivatives as nk-1 receptor antagonists |
AU2001278626A Abandoned AU2001278626A1 (en) | 2000-08-22 | 2001-08-17 | Tetrahydropyran derivatives as nk-1 receptor antagonists |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001278626A Abandoned AU2001278626A1 (en) | 2000-08-22 | 2001-08-17 | Tetrahydropyran derivatives as nk-1 receptor antagonists |
Country Status (6)
Country | Link |
---|---|
US (1) | US6489343B2 (en) |
AU (2) | AU2001279950A1 (en) |
GB (1) | GB0020721D0 (en) |
JO (1) | JO2231B1 (en) |
PE (1) | PE20020436A1 (en) |
WO (2) | WO2002016343A1 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001243297A1 (en) * | 2000-02-29 | 2001-09-12 | Merck Frosst Canada And Co. | Method for treating or preventing depression |
GB0121874D0 (en) * | 2001-09-10 | 2001-10-31 | Merck Sharp & Dohme | Therapeutic agents |
GB0217068D0 (en) * | 2002-07-23 | 2002-08-28 | Merck Sharp & Dohme | Therapeutic agents |
US7393858B2 (en) | 2003-03-07 | 2008-07-01 | Merck Sharp & Dohme Ltd. | Tetrahydropyran compounds as tachykinin antagonists |
EP1824811B1 (en) * | 2004-11-22 | 2009-07-01 | Mallinckrodt, Inc. | Process for the purification of benzphetamine hydrochloride |
DE602005014138D1 (en) * | 2004-11-30 | 2009-06-04 | Mallinckrodt Inc | METHOD FOR CRYSTALLIZING BENZPHETAMINE |
KR20070121013A (en) * | 2005-04-22 | 2007-12-26 | 다이이찌 산쿄 가부시키가이샤 | Heterocyclic compound |
WO2006125529A1 (en) * | 2005-05-25 | 2006-11-30 | Merck Patent Gmbh | Formyltetrahydropyrans, method for the production thereof and use thereof in the production of liquid crystal compounds |
MX2009007916A (en) | 2007-01-24 | 2009-07-31 | Glaxo Group Ltd | Pharmaceutical compositions comprising 3, 5-diamin0-6- (2, 3-dichl0phenyl) -l, 2, 4-triazine or r (-) -2, 4-diamino-5- (2, 3-dichlorophenyl) -6-fluoromethyl pyrimidine and an nk1. |
FR3002733B1 (en) | 2013-03-04 | 2015-08-14 | Servier Lab | NOVEL SALT OF THE ABEXINOSTAT, THE CRYSTALLINE FORM ASSOCIATED WITH THEM, THE PROCESS FOR PREPARING THEM AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
KR20170043648A (en) | 2014-09-03 | 2017-04-21 | 파마싸이클릭스 엘엘씨 | 3-[]-n-2-[4-]-1--2- novel salts of 3-dimethylaminomethyl-n-2-[4-hydroxycarbamoylphenoxy]ethyl-1-benzofuran-2-carboxamide related crystalline forms method for preparing the same and pharmaceutical compositions containing the same |
RU2750702C1 (en) * | 2017-12-13 | 2021-07-01 | Джинфлит Терапьютикс (Шанхай) Инк. | CRYSTALLINE AND SALT FORMS OF THE TGF-βR1 INHIBITOR AND THE METHOD OF OBTAINING THEM |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9301920D0 (en) | 1993-02-01 | 1993-03-17 | Foundation For Ethnobiology Th | Polycetylenes |
EP1462450B1 (en) * | 1993-12-29 | 2007-06-13 | MERCK SHARP & DOHME LTD. | Substituted morpholine derivatives and their use as therapeutic agents |
CA2334609A1 (en) * | 1998-06-11 | 1999-12-16 | Merck Sharp & Dohme Limited | Use of a nk-1 receptor antagonist for treating psychiatric disorders |
GB9812662D0 (en) * | 1998-06-11 | 1998-08-12 | Merck Sharp & Dohme | Therapeutic use |
AU4278199A (en) * | 1998-06-11 | 1999-12-30 | Merck Sharp & Dohme Limited | Use of a nk-1 receptor antagonist for treating psychiatric disorders |
CO5150225A1 (en) | 1999-03-19 | 2002-04-29 | Merck Sharp & Dohme | DERIVATIVES OF TETRAHYDROPIRANE AND ITS USE AS THERAPEUTIC AGENTS |
-
2000
- 2000-08-22 GB GBGB0020721.7A patent/GB0020721D0/en not_active Ceased
-
2001
- 2001-08-14 JO JO2001133A patent/JO2231B1/en active
- 2001-08-17 AU AU2001279950A patent/AU2001279950A1/en not_active Abandoned
- 2001-08-17 WO PCT/GB2001/003685 patent/WO2002016343A1/en active Application Filing
- 2001-08-17 WO PCT/GB2001/003699 patent/WO2002016344A1/en active Application Filing
- 2001-08-17 AU AU2001278626A patent/AU2001278626A1/en not_active Abandoned
- 2001-08-20 US US09/933,064 patent/US6489343B2/en not_active Expired - Fee Related
- 2001-08-20 PE PE2001000828A patent/PE20020436A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2002016343A1 (en) | 2002-02-28 |
GB0020721D0 (en) | 2000-10-11 |
WO2002016344A1 (en) | 2002-02-28 |
JO2231B1 (en) | 2004-10-07 |
US20020035132A1 (en) | 2002-03-21 |
PE20020436A1 (en) | 2002-06-14 |
US6489343B2 (en) | 2002-12-03 |
AU2001278626A1 (en) | 2002-03-04 |
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