AU2001278319A1 - Amyloid targeting imaging agents and uses thereof - Google Patents

Amyloid targeting imaging agents and uses thereof

Info

Publication number
AU2001278319A1
AU2001278319A1 AU2001278319A AU7831901A AU2001278319A1 AU 2001278319 A1 AU2001278319 A1 AU 2001278319A1 AU 2001278319 A AU2001278319 A AU 2001278319A AU 7831901 A AU7831901 A AU 7831901A AU 2001278319 A1 AU2001278319 A1 AU 2001278319A1
Authority
AU
Australia
Prior art keywords
imaging agents
targeting imaging
amyloid targeting
amyloid
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001278319A
Inventor
Robert Chalifour
Francine Gervais
Xianqi Kong
David Migneault
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bellus Health Inc
Original Assignee
Neurochem Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurochem Inc filed Critical Neurochem Inc
Publication of AU2001278319A1 publication Critical patent/AU2001278319A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2001278319A 2000-07-25 2001-07-25 Amyloid targeting imaging agents and uses thereof Abandoned AU2001278319A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22080800P 2000-07-25 2000-07-25
US60/220,808 2000-07-25
US09/915,092 US20020115717A1 (en) 2000-07-25 2001-07-24 Amyloid targeting imaging agents and uses thereof
US09/915,092 2001-07-24
PCT/CA2001/001071 WO2002007781A2 (en) 2000-07-25 2001-07-25 Amyloid targeting imaging agents and uses thereof

Publications (1)

Publication Number Publication Date
AU2001278319A1 true AU2001278319A1 (en) 2002-02-05

Family

ID=26915211

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001278319A Abandoned AU2001278319A1 (en) 2000-07-25 2001-07-25 Amyloid targeting imaging agents and uses thereof

Country Status (6)

Country Link
US (1) US20020115717A1 (en)
EP (1) EP1303311A2 (en)
AU (1) AU2001278319A1 (en)
CA (1) CA2416617A1 (en)
NO (1) NO20030397L (en)
WO (1) WO2002007781A2 (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001003680A2 (en) * 1999-07-09 2001-01-18 Isis Innovation Limited Compounds for inhibiting diseases and preparing cells for transplantation
WO2002064084A2 (en) * 2000-11-02 2002-08-22 Cornell Research Foundation, Inc. In vivo multiphoton diagnostic detection and imaging of a neurodegenerative disease
US20040049134A1 (en) * 2002-07-02 2004-03-11 Tosaya Carol A. System and methods for treatment of alzheimer's and other deposition-related disorders of the brain
DE10230141B4 (en) * 2002-07-04 2004-07-15 Priontype Gmbh Method and kit for the enrichment and detection of modified prion proteins (PrPSc)
US20040204344A1 (en) * 2003-01-22 2004-10-14 Xudong Huang Amyloid-binding, metal-chelating agents
US7244764B2 (en) * 2003-06-23 2007-07-17 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
US20070010573A1 (en) * 2003-06-23 2007-01-11 Xianqi Kong Methods and compositions for treating amyloid-related diseases
JP2007516938A (en) * 2003-06-23 2007-06-28 ニューロケム （インターナショナル） リミテッド Methods and compositions for treating amyloid-related diseases
US20050214222A1 (en) * 2004-02-13 2005-09-29 Mckinnon Stuart J In vivo imaging of amyloid plaques in glaucoma using intravenous injectable dyes
US7803351B2 (en) * 2004-08-20 2010-09-28 Washington University Blood brain barrier permeation peptides
EP1828111A2 (en) * 2004-11-12 2007-09-05 Neurochem (International) Limited Methods and fluorinated compositions for treating amyloid-related diseases
WO2006085149A2 (en) 2004-12-22 2006-08-17 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
US9335331B2 (en) * 2005-04-11 2016-05-10 Cornell Research Foundation, Inc. Multiplexed biomarkers for monitoring the Alzheimer's disease state of a subject
TW200716088A (en) * 2005-04-15 2007-05-01 Neurochem Int Ltd Formulations and methods for treating amyloidosis
US20070049638A1 (en) * 2005-07-21 2007-03-01 Neurochem (International) Limited Polymorphic forms of 3-amino-1-propanesulfonic acid
WO2007125385A2 (en) * 2005-12-22 2007-11-08 Neurochem (International) Limited Treatment of renal disorders, diabetic nephopathy and dyslipidemias
JP5607930B2 (en) 2006-10-12 2014-10-15 ビーエイチアイ リミテッド パートナーシップ Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid
AU2007337806A1 (en) * 2006-12-22 2008-07-03 Bellus Health (International) Limited Methods, compounds, and compositions for treating metabolic disorders and diabetes
SI2247558T1 (en) 2008-02-14 2022-07-29 Eli Lilly And Company Novel imaging agents for detecting neurological dysfunction
WO2010087313A1 (en) * 2009-01-29 2010-08-05 株式会社林原生物化学研究所 Neurite elongation stimulator
EP2397139B1 (en) * 2009-01-29 2014-09-17 Hayashibara Co., Ltd. Anti-neurodegenerative disease agent
WO2010087315A1 (en) * 2009-01-29 2010-08-05 株式会社林原生物化学研究所 Anti-alzheimer’s disease agent
US9023767B2 (en) * 2009-05-07 2015-05-05 Memorial Sloan-Kettering Cancer Center γ-Secretase substrates and methods of use
CN103502466A (en) 2010-09-07 2014-01-08 斯隆－凯特林纪念癌症中心 Methods and compositions for gamma-secretase assay
US9683017B2 (en) 2014-07-17 2017-06-20 University Tennessee Research Foundation Inhibitory peptides of viral infection
US10213506B2 (en) 2014-08-26 2019-02-26 University Of Tennessee Research Foundation Targeting immunotherapy for amyloidosis
US10493172B2 (en) 2016-06-02 2019-12-03 California Institute Of Technology Gas-filled structures and related compositions, methods and systems to image a target site
US11761008B2 (en) 2019-01-07 2023-09-19 California Institute Of Technology Gas vesicle expression systems, gas vesicle constructs and related genetic circuits, vectors, mammalian cells, hosts, compositions, methods and systems
US11786218B2 (en) 2019-01-07 2023-10-17 California Institute Of Technology Burst ultrasound reconstruction with signal templates and related methods and systems
WO2020198728A1 (en) * 2019-03-28 2020-10-01 California Institute Of Technology Compositions, methods and systems for gas vesicle based cavitation
CN111398465B (en) * 2020-04-03 2021-08-10 北京先通国际医药科技股份有限公司 Method for measuring precursor FCPHA of PET imaging agent and cis-isomer thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840294A (en) * 1993-03-29 1998-11-24 Queen's University At Kingston Method for treating amyloidosis
WO1997041856A1 (en) * 1996-05-08 1997-11-13 Massachusetts Institute Of Technology ORGANOMETALLIC LIGANDS FOR THE LOCALIZATION AND QUANTIFICATION OF AMYLOID IN VIVO AND $i(IN VITRO)
US6261537B1 (en) * 1996-10-28 2001-07-17 Nycomed Imaging As Diagnostic/therapeutic agents having microbubbles coupled to one or more vectors
WO2001039796A2 (en) * 1999-11-29 2001-06-07 Neurochem Inc. Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
WO2001087354A2 (en) * 2000-05-17 2001-11-22 Bristol-Myers Squibb Pharma Company Use of small molecule radioligands for diagnostic imaging
US6589504B1 (en) * 2000-09-22 2003-07-08 Pharmacia & Upjohn Company Compounds and methods for diagnosing and treating amyloid-related conditions

Also Published As

Publication number Publication date
WO2002007781A3 (en) 2002-10-31
NO20030397L (en) 2003-03-24
US20020115717A1 (en) 2002-08-22
EP1303311A2 (en) 2003-04-23
NO20030397D0 (en) 2003-01-24
WO2002007781A2 (en) 2002-01-31
CA2416617A1 (en) 2002-01-31

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