AU2001276610A1 - Mammal 2p domain mechano-sensitive k+ channel, cloning and applications thereof - Google Patents

Mammal 2p domain mechano-sensitive k+ channel, cloning and applications thereof

Info

Publication number
AU2001276610A1
AU2001276610A1 AU2001276610A AU7661001A AU2001276610A1 AU 2001276610 A1 AU2001276610 A1 AU 2001276610A1 AU 2001276610 A AU2001276610 A AU 2001276610A AU 7661001 A AU7661001 A AU 7661001A AU 2001276610 A1 AU2001276610 A1 AU 2001276610A1
Authority
AU
Australia
Prior art keywords
mechano
cloning
mammal
domain
sensitive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001276610A
Inventor
Michel Lazdunski
Florian Lesage
Georges Romey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Publication of AU2001276610A1 publication Critical patent/AU2001276610A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
AU2001276610A 2000-06-27 2001-06-27 Mammal 2p domain mechano-sensitive k+ channel, cloning and applications thereof Abandoned AU2001276610A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21455900P 2000-06-27 2000-06-27
US60/214,559 2000-06-27
US09/892,360 US6962976B2 (en) 2000-06-27 2001-06-27 Human TREK2, a stretch- and arachidonic acid-sensitive K+ channel activated by inhalational anesthetics and niluzole
US09/892,360 2001-06-27
PCT/IB2001/001436 WO2002000715A2 (en) 2000-06-27 2001-06-27 Mammal 2p domain mechano-sensitive k+ channel, cloning and applications thereof

Publications (1)

Publication Number Publication Date
AU2001276610A1 true AU2001276610A1 (en) 2002-01-08

Family

ID=26909114

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001276610A Abandoned AU2001276610A1 (en) 2000-06-27 2001-06-27 Mammal 2p domain mechano-sensitive k+ channel, cloning and applications thereof

Country Status (6)

Country Link
US (1) US6962976B2 (en)
EP (1) EP1297138A2 (en)
JP (1) JP2004501627A (en)
AU (1) AU2001276610A1 (en)
CA (1) CA2413747A1 (en)
WO (1) WO2002000715A2 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020103115A1 (en) * 2000-09-19 2002-08-01 Karl Guegler Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2005054861A1 (en) * 2003-11-22 2005-06-16 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with potassium channel subfamily k, member 10 (kcnk10)
GB0505480D0 (en) * 2005-03-18 2005-04-20 Isis Innovation Screening method for compounds with anaesthetic property
AR059898A1 (en) 2006-03-15 2008-05-07 Janssen Pharmaceutica Nv DERIVATIVES OF 3-CIANO-PIRIDONA 1,4-DISUSTITUTED AND ITS USE AS ALLOSTERIC MODULATORS OF MGLUR2 RECEIVERS
WO2007114925A2 (en) * 2006-04-04 2007-10-11 The Trustees Of Columbia University Of In The City Of New York Two pore channels as a therapeutic target to protect against myocardial ischemia and as an adjuvant in cardiac surgery
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
TW200845978A (en) 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
CN101848893B (en) 2007-09-14 2012-06-06 奥梅-杨森制药有限公司 1,3-disubstituted 4-(aryl-x-phenyl)-1h-pyridin-2-ones
MY152078A (en) 2007-09-14 2014-08-15 Ortho Mcneil Janssen Pharm 1',3'-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2h,1'h-[1,4']bipyridinyl-2'-ones
CA2698929C (en) 2007-09-14 2016-01-19 Addex Pharma S.A. 1,3-disubstituted-4-phenyl-1h-pyridin-2-ones
MX2010005110A (en) 2007-11-14 2010-09-09 Ortho Mcneil Janssen Pharm Imidazo[1,2-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors.
JP5547194B2 (en) 2008-09-02 2014-07-09 ジャンセン ファーマシューティカルズ， インコーポレイテッド． 3-Azabicyclo [3.1.0] hexyl derivatives as modulators of metabotropic glutamate receptors
EP2346505B1 (en) 2008-10-16 2014-04-23 Janssen Pharmaceuticals, Inc. Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors
CN102232074B (en) 2008-11-28 2014-12-03 奥梅-杨森制药有限公司 Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors
MY153913A (en) 2009-05-12 2015-04-15 Janssen Pharmaceuticals Inc 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
AU2010246607B2 (en) 2009-05-12 2012-09-27 Addex Pharma S.A. 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors
MX2011011964A (en) 2009-05-12 2012-02-23 Janssen Pharmaceuticals Inc 1,2,4-triazolo [4,3-a] pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders.
PL2649069T3 (en) 2010-11-08 2016-01-29 Janssen Pharmaceuticals Inc 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
WO2012062759A1 (en) 2010-11-08 2012-05-18 Janssen Pharmaceuticals, Inc. 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
CN103261195B (en) 2010-11-08 2015-09-02 杨森制药公司 The purposes of 1,2,4-triazolo [4,3-a] pyridine derivate and the positive allosteric modulators as MGLUR2 acceptor thereof
JO3368B1 (en) 2013-06-04 2019-03-13 Janssen Pharmaceutica Nv 6,7-DIHYDROPYRAZOLO[1,5-a]PYRAZIN-4(5H)-ONE COMPOUNDS AND THEIR USE AS NEGATIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
JO3367B1 (en) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv 1,2,4-TRIAZOLO[4,3-a]PYRIDINE COMPOUNDS AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
HUE045610T2 (en) 2014-01-21 2020-01-28 Janssen Pharmaceutica Nv Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use
EA033889B1 (en) 2014-01-21 2019-12-05 Янссен Фармацевтика Нв Combination comprising sv2a ligand and positive allosteric modulator of metabotropic glutamatergic receptor subtype 2

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1051485A1 (en) * 1998-01-27 2000-11-15 Smithkline Beecham Plc Trek-1 like two pore potassium channel
WO2001085788A2 (en) * 2000-05-10 2001-11-15 Pharmacia & Upjohn Company Human ion channels

Also Published As

Publication number Publication date
WO2002000715A3 (en) 2002-12-05
EP1297138A2 (en) 2003-04-02
CA2413747A1 (en) 2002-01-03
US6962976B2 (en) 2005-11-08
US20040101833A1 (en) 2004-05-27
WO2002000715A2 (en) 2002-01-03
JP2004501627A (en) 2004-01-22

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