AU2001274827A1 - Porphyrin-based neutron capture agents for cancer therapy - Google Patents
Porphyrin-based neutron capture agents for cancer therapyInfo
- Publication number
- AU2001274827A1 AU2001274827A1 AU2001274827A AU7482701A AU2001274827A1 AU 2001274827 A1 AU2001274827 A1 AU 2001274827A1 AU 2001274827 A AU2001274827 A AU 2001274827A AU 7482701 A AU7482701 A AU 7482701A AU 2001274827 A1 AU2001274827 A1 AU 2001274827A1
- Authority
- AU
- Australia
- Prior art keywords
- porphyrin
- cancer therapy
- neutron capture
- capture agents
- based neutron
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000011275 oncology therapy Methods 0.000 title 1
- 150000004032 porphyrins Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/009—Neutron capture therapy, e.g. using uranium or non-boron material
- A61K41/0095—Boron neutron capture therapy, i.e. BNCT, e.g. using boronated porphyrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/05—Cyclic compounds having at least one ring containing boron but no carbon in the ring
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20316000P | 2000-05-09 | 2000-05-09 | |
US60203160 | 2000-05-09 | ||
PCT/US2001/015433 WO2001085736A1 (en) | 2000-05-09 | 2001-05-09 | Porphyrin-based neutron capture agents for cancer therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001274827A1 true AU2001274827A1 (en) | 2001-11-20 |
Family
ID=22752759
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001274827A Abandoned AU2001274827A1 (en) | 2000-05-09 | 2001-05-09 | Porphyrin-based neutron capture agents for cancer therapy |
Country Status (3)
Country | Link |
---|---|
US (1) | US7067653B2 (en) |
AU (1) | AU2001274827A1 (en) |
WO (1) | WO2001085736A1 (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2483687A1 (en) * | 2002-05-13 | 2003-11-20 | Alexza Molecular Delivery Corporation | Delivery of drug amines through an inhalation route |
US7267990B2 (en) * | 2002-11-15 | 2007-09-11 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Chelation of charged and uncharged molecules with porphyrin-based compounds |
US6989443B2 (en) | 2004-06-28 | 2006-01-24 | Brookhaven Science Associates, Llc | Carboranylporphyrins and uses thereof |
US6995260B2 (en) * | 2004-05-20 | 2006-02-07 | Brookhaven Science Associates, Llc | Carboranylporphyrins and uses thereof |
US8071760B2 (en) | 2005-10-25 | 2011-12-06 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Boron-containing porphyrin compounds and their uses |
US20120075577A1 (en) | 2006-03-20 | 2012-03-29 | Ishak Andrew W | High performance selective light wavelength filtering providing improved contrast sensitivity |
US8882267B2 (en) | 2006-03-20 | 2014-11-11 | High Performance Optics, Inc. | High energy visible light filter systems with yellowness index values |
US9377569B2 (en) | 2006-03-20 | 2016-06-28 | High Performance Optics, Inc. | Photochromic ophthalmic systems that selectively filter specific blue light wavelengths |
US8287839B2 (en) * | 2006-12-04 | 2012-10-16 | Brookhaven Science Associates, Llc | Carboranylporphyrins and uses thereof |
US8444953B2 (en) * | 2007-03-22 | 2013-05-21 | Brookhaven Science Associates, Llc | Symmetric and asymmetric halogen-containing metallocarboranylporphyrins and uses thereof |
US20080279781A1 (en) * | 2007-05-10 | 2008-11-13 | Brookhaven Science Associates, Llc | Glycosylated Carboranylporphyrins and Uses Thereof |
CN103988329B (en) * | 2011-12-12 | 2016-07-13 | 新日铁住金化学株式会社 | Organic electroluminescent device material and the organic electroluminescent device using it |
CN102993206B (en) * | 2012-12-18 | 2015-07-22 | 聊城大学 | Method for synthesising tetraphenylporphyrin metal complex via one-step process |
US9798163B2 (en) | 2013-05-05 | 2017-10-24 | High Performance Optics, Inc. | Selective wavelength filtering with reduced overall light transmission |
RU2551539C2 (en) * | 2013-08-01 | 2015-05-27 | Федеральное Государственное Бюджетное Учреждение Науки Институт Биохимической Физики Им. Н.М. Эмануэля Российской Академии Наук (Ибхф Ран) | Method of producing borated porphyrins |
US9683102B2 (en) * | 2014-05-05 | 2017-06-20 | Frontier Scientific, Inc. | Photo-stable and thermally-stable dye compounds for selective blue light filtered optic |
RU2615770C1 (en) * | 2015-12-21 | 2017-04-11 | Общество с ограниченной ответственностью "Пермская химическая компания" | Borated derivatives of fluorinated bacteriochlorines and their metal complexes with antitumor activity |
CN115916195A (en) * | 2020-07-21 | 2023-04-04 | 安科生命科学有限公司 | Therapeutic agents and uses thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4959356A (en) * | 1989-05-26 | 1990-09-25 | The United States Of America As Represented By The United States Department Of Energy | Porphyrins for boron neutron capture therapy |
US5877165A (en) * | 1995-11-02 | 1999-03-02 | Brookhaven Science Associates | Boronated porhyrins and methods for their use |
-
2001
- 2001-05-09 AU AU2001274827A patent/AU2001274827A1/en not_active Abandoned
- 2001-05-09 WO PCT/US2001/015433 patent/WO2001085736A1/en active Application Filing
- 2001-05-09 US US10/258,948 patent/US7067653B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20040014737A1 (en) | 2004-01-22 |
US7067653B2 (en) | 2006-06-27 |
WO2001085736A1 (en) | 2001-11-15 |
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