AU2001274021A1 - Active substance combination containing an opioid having a fentanyl-type structure and ketamine - Google Patents

Active substance combination containing an opioid having a fentanyl-type structure and ketamine

Info

Publication number
AU2001274021A1
AU2001274021A1 AU2001274021A AU7402101A AU2001274021A1 AU 2001274021 A1 AU2001274021 A1 AU 2001274021A1 AU 2001274021 A AU2001274021 A AU 2001274021A AU 7402101 A AU7402101 A AU 7402101A AU 2001274021 A1 AU2001274021 A1 AU 2001274021A1
Authority
AU
Australia
Prior art keywords
fentanyl
ketamine
opioid
active substance
type structure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001274021A
Inventor
Boris Chizh
Thomas Christoph
Werner Englberger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
Original Assignee
Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH
Publication of AU2001274021A1 publication Critical patent/AU2001274021A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/452—Piperidinium derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
AU2001274021A 2000-05-26 2001-05-10 Active substance combination containing an opioid having a fentanyl-type structure and ketamine Abandoned AU2001274021A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10025946 2000-05-26
DE10025946A DE10025946A1 (en) 2000-05-26 2000-05-26 drug combination
PCT/EP2001/005348 WO2001091753A1 (en) 2000-05-26 2001-05-10 Active substance combination containing an opioid having a fentanyl-type structure and ketamine

Publications (1)

Publication Number Publication Date
AU2001274021A1 true AU2001274021A1 (en) 2001-12-11

Family

ID=7643550

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001274021A Abandoned AU2001274021A1 (en) 2000-05-26 2001-05-10 Active substance combination containing an opioid having a fentanyl-type structure and ketamine

Country Status (10)

Country Link
US (1) US20040092531A1 (en)
EP (1) EP1289528A1 (en)
JP (1) JP2003534378A (en)
AU (1) AU2001274021A1 (en)
CA (1) CA2406976A1 (en)
DE (1) DE10025946A1 (en)
HU (1) HUP0301972A3 (en)
MX (1) MXPA02011610A (en)
NZ (1) NZ521878A (en)
WO (1) WO2001091753A1 (en)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10141650C1 (en) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Safe transdermal therapeutic system for administration of fentanyl or analogous analgesics, having matrix layer of carboxy group-free polyacrylate adhesive providing high permeation rate
US7959946B2 (en) 2002-09-20 2011-06-14 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US7785627B2 (en) 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
WO2004026241A2 (en) * 2002-09-20 2004-04-01 Andrx Labs Llc Multistage formulation containing a biguanide and thiazolidindione derivatives
US8084058B2 (en) * 2002-09-20 2011-12-27 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US9060941B2 (en) * 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
CA2550023C (en) * 2003-12-16 2011-04-12 Cnsbio Pty Ltd Treatment of neuropathic pain
EP1789028A2 (en) * 2004-08-24 2007-05-30 Neuromolecular Pharmaceuticals Inc Compositions for treating nociceptive pain
US20070104763A1 (en) * 2005-11-10 2007-05-10 Navinta Llc Composition of fentanyl citrate oral solid transmucosal dosage form, excipient and binding material therefore, and methods of making
US9289583B2 (en) * 2006-01-06 2016-03-22 Acelrx Pharmaceuticals, Inc. Methods for administering small volume oral transmucosal dosage forms using a dispensing device
US9066847B2 (en) * 2007-01-05 2015-06-30 Aceirx Pharmaceuticals, Inc. Storage and dispensing devices for administration of oral transmucosal dosage forms
US8202535B2 (en) * 2006-01-06 2012-06-19 Acelrx Pharmaceuticals, Inc. Small-volume oral transmucosal dosage forms
US8753308B2 (en) 2006-01-06 2014-06-17 Acelrx Pharmaceuticals, Inc. Methods for administering small volume oral transmucosal dosage forms using a dispensing device
US8535714B2 (en) 2006-01-06 2013-09-17 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8252328B2 (en) * 2006-01-06 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
CN101495080B (en) * 2006-01-06 2013-10-23 阿塞尔Rx制药有限公司 Drug storage and dispensing devices and systems comprising same
US8357114B2 (en) 2006-01-06 2013-01-22 Acelrx Pharmaceuticals, Inc. Drug dispensing device with flexible push rod
US8865743B2 (en) 2006-01-06 2014-10-21 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8252329B2 (en) 2007-01-05 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US20070260491A1 (en) * 2006-05-08 2007-11-08 Pamela Palmer System for delivery and monitoring of administration of controlled substances
US8173666B2 (en) 2007-03-12 2012-05-08 Nektar Therapeutics Oligomer-opioid agonist conjugates
US10512644B2 (en) 2007-03-12 2019-12-24 Inheris Pharmaceuticals, Inc. Oligomer-opioid agonist conjugates
WO2009131794A1 (en) * 2008-03-27 2009-10-29 University Of Kentucky Research Foundation Opioid-ketamine and norketamine codrug combinations for pain management
CA2734333A1 (en) * 2008-09-16 2010-03-25 Nektar Therapeutics Pegylated opioids with low potential for abuse
US8945592B2 (en) 2008-11-21 2015-02-03 Acelrx Pharmaceuticals, Inc. Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same
JP2013523780A (en) * 2010-04-02 2013-06-17 オールトランツ インコーポレイティド Abuse deterrent transdermal preparations of opiate agonists and agonist-antagonists
TWI630194B (en) 2013-03-14 2018-07-21 凱立拉製藥公司 Bicyclic analgesic compounds
WO2015065547A1 (en) 2013-10-31 2015-05-07 Cima Labs Inc. Immediate release abuse-deterrent granulated dosage forms
US10189780B2 (en) 2013-12-12 2019-01-29 Zeno Royalties & Milestones, LLC Bicyclic alkyl compounds and synthesis
EP3114107B1 (en) 2014-03-07 2020-07-22 Recurium IP Holdings, LLC Propellane derivates and synthesis
EP3193855B1 (en) 2014-09-17 2021-05-19 Recurium IP Holdings, LLC Bicyclic compounds
MY187877A (en) 2014-12-23 2021-10-26 Acelrx Pharmaceuticals Inc Systems, devices and methods for dispensing oral transmucosal dosage forms
US20190060257A1 (en) * 2016-03-16 2019-02-28 Zeno Royalties & Milestones, LLC Analgesic compounds
US9650338B1 (en) * 2016-07-29 2017-05-16 VDM Biochemicals, Inc. Opioid antagonist compounds and methods of making and using
NZ759268A (en) 2017-05-15 2022-07-01 Recurium Ip Holdings Llc Bicyclo[1.1.1]pentyl compounds as analgesics
US11324707B2 (en) 2019-05-07 2022-05-10 Clexio Biosciences Ltd. Abuse-deterrent dosage forms containing esketamine
US11160799B2 (en) * 2019-10-22 2021-11-02 Cessatech A/S Pediatric combination

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3254124A (en) * 1962-06-29 1966-05-31 Parke Davis & Co Aminoketones and methods for their production
US5321012A (en) * 1993-01-28 1994-06-14 Virginia Commonwealth University Medical College Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance
US5635204A (en) * 1994-03-04 1997-06-03 Montefiore Medical Center Method for transdermal induction of anesthesia, analgesia or sedation
WO1997007750A1 (en) * 1995-08-30 1997-03-06 Weg Stuart L Administration of ketamine to manage pain and to reduce drug dependency
ATE344035T1 (en) * 1998-07-16 2006-11-15 Memorial Sloan Kettering Inst TOPICAL COMPOSITION CONTAINING AN OPIOID ANALGESIC AND AN NMDA ANTAGONIST

Also Published As

Publication number Publication date
JP2003534378A (en) 2003-11-18
CA2406976A1 (en) 2002-10-22
US20040092531A1 (en) 2004-05-13
EP1289528A1 (en) 2003-03-12
HUP0301972A3 (en) 2005-06-28
NZ521878A (en) 2005-08-26
WO2001091753A1 (en) 2001-12-06
DE10025946A1 (en) 2001-11-29
MXPA02011610A (en) 2003-05-14
HUP0301972A2 (en) 2003-11-28

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Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application