AU2001273999A1 - Fluorescein isothiocyanate (fitc) sinistrin, its production and use - Google Patents

Fluorescein isothiocyanate (fitc) sinistrin, its production and use

Info

Publication number
AU2001273999A1
AU2001273999A1 AU2001273999A AU7399901A AU2001273999A1 AU 2001273999 A1 AU2001273999 A1 AU 2001273999A1 AU 2001273999 A AU2001273999 A AU 2001273999A AU 7399901 A AU7399901 A AU 7399901A AU 2001273999 A1 AU2001273999 A1 AU 2001273999A1
Authority
AU
Australia
Prior art keywords
sinistrin
fitc
production
fluorescein isothiocyanate
diagnostic agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001273999A
Inventor
Carsten Deus
Norbert Gretz
Uwe Kraemer
Rudolf Reiter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HEINZ MICHAEL HEIN
Original Assignee
HEINZ MICHAEL HEIN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HEINZ MICHAEL HEIN filed Critical HEINZ MICHAEL HEIN
Publication of AU2001273999A1 publication Critical patent/AU2001273999A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0054—Macromolecular compounds, i.e. oligomers, polymers, dendrimers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
    • A61K49/0043—Fluorescein, used in vivo
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0051—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Fructofuranans, e.g. beta-2,6-D-fructofuranan, i.e. levan; Derivatives thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

The invention concerns fluorescein isothiocyanate-sinistrin (FITC-sinistrin), a method for its production, its use as a marker substance in a diagnostic agent and a corresponding diagnostic agent.
AU2001273999A 2000-05-11 2001-05-08 Fluorescein isothiocyanate (fitc) sinistrin, its production and use Abandoned AU2001273999A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10023051A DE10023051B4 (en) 2000-05-11 2000-05-11 Process for the preparation of fluorescein isothiocyanate sinistrin, its use and diagnostic preparation containing fluorescein isothiocyanate sinistrin
DE10023051 2000-05-11
PCT/EP2001/005172 WO2001085799A1 (en) 2000-05-11 2001-05-08 Fluorescein isothiocyanate (fitc) sinistrin, its production and use

Publications (1)

Publication Number Publication Date
AU2001273999A1 true AU2001273999A1 (en) 2001-11-20

Family

ID=7641631

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001273999A Abandoned AU2001273999A1 (en) 2000-05-11 2001-05-08 Fluorescein isothiocyanate (fitc) sinistrin, its production and use

Country Status (9)

Country Link
US (1) US6995019B2 (en)
EP (1) EP1290035B1 (en)
JP (1) JP4189153B2 (en)
AT (1) ATE259379T1 (en)
AU (1) AU2001273999A1 (en)
CA (1) CA2407795C (en)
DE (2) DE10023051B4 (en)
ES (1) ES2214423T3 (en)
WO (1) WO2001085799A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10209821A1 (en) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Coupling of proteins to a modified polysaccharide
US20030212735A1 (en) 2002-05-13 2003-11-13 Nvidia Corporation Method and apparatus for providing an integrated network of processors
BR0314107A (en) * 2002-09-11 2005-07-19 Fresenius Kabi De Gmbh Production method of hydroxyalkyl starch derivatives
WO2005014655A2 (en) 2003-08-08 2005-02-17 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein
DE102004045748A1 (en) * 2004-09-21 2006-04-06 Roche Diagnostics Gmbh Stoichiometrically defined dye-labeled substances for measuring the glomerular filtration rate, their preparation and use
DE102007007738A1 (en) 2007-02-09 2008-08-14 Südzucker AG Mannheim/Ochsenfurt Color-labeled oligo- or polysaccharides
DK2317911T3 (en) 2008-08-22 2019-01-28 Medibeacon Inc TRANSCUTAN ORGAN FUNCTION MEASUREMENT
EP3060098B1 (en) * 2013-10-22 2019-02-27 MediBeacon Inc. Improved transcutaneous organ function measurement
EP2944326B1 (en) 2014-05-16 2018-11-21 Cyanagen Srl Tricarbocyanine-cyclodextrin-conjugates and their use for the diagnosis of kidney diseases
CN115120241A (en) 2017-01-30 2022-09-30 麦迪贝肯有限公司 Non-invasive monitoring method using diffuse reflectance corrected fluorescent tracers
US11261165B2 (en) 2019-01-16 2022-03-01 Medibeacon Inc. Two piece sensor assembly and method of use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4101910A1 (en) * 1991-01-23 1992-07-30 Laevosan Gmbh & Co Kg METHOD FOR PRODUCING A PYROGEN-FREE GOOD WATER-SOLUBLE FRUCTAN AND A KIDNEY DIAGNOSTIC THAT CONTAINS SUCH A FRUCTAN
US5976820A (en) * 1995-08-28 1999-11-02 Jolley; Michael E. Detection of antibodies to bacterial antigens by flourescence polarization
DE19629656A1 (en) 1996-07-23 1998-01-29 Boehringer Mannheim Gmbh Diagnostic test carrier with multilayer test field and method for the determination of analyte with its aid
DE19649971A1 (en) * 1996-11-19 1998-05-28 Diagnostikforschung Inst Optical diagnostics for the diagnosis of neurodegenerative diseases using near-infrared radiation (NIR radiation)
EP0934986A1 (en) * 1997-12-17 1999-08-11 Roche Diagnostics GmbH Dye-polysaccharide or -cyclosaccharide conjugates and their use as diagnostic agent
US6656451B1 (en) * 2000-10-16 2003-12-02 Mallinckrodt, Inc. Indole compounds as novel dyes for organ function monitoring

Also Published As

Publication number Publication date
CA2407795C (en) 2006-03-14
ES2214423T3 (en) 2004-09-16
EP1290035A1 (en) 2003-03-12
US6995019B2 (en) 2006-02-07
JP2003532759A (en) 2003-11-05
WO2001085799A1 (en) 2001-11-15
JP4189153B2 (en) 2008-12-03
DE10023051A1 (en) 2001-11-22
US20040022730A1 (en) 2004-02-05
ATE259379T1 (en) 2004-02-15
DE10023051B4 (en) 2004-02-19
DE50101479D1 (en) 2004-03-18
CA2407795A1 (en) 2002-10-29
EP1290035B1 (en) 2004-02-11

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