AU2001268162A1 - Methods for producing chiral chromones, chromanes, amino substituted chromanes and intermediates therefor - Google Patents

Methods for producing chiral chromones, chromanes, amino substituted chromanes and intermediates therefor

Info

Publication number
AU2001268162A1
AU2001268162A1 AU2001268162A AU6816201A AU2001268162A1 AU 2001268162 A1 AU2001268162 A1 AU 2001268162A1 AU 2001268162 A AU2001268162 A AU 2001268162A AU 6816201 A AU6816201 A AU 6816201A AU 2001268162 A1 AU2001268162 A1 AU 2001268162A1
Authority
AU
Australia
Prior art keywords
chromanes
chromones
methods
amino substituted
intermediates therefor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001268162A
Inventor
Barbara Briggs
Marvin Hansen
James Kanter
John J. G. Mullins
Gerd Ruhter
Uko Udodong
Daniel Verral Ii
Milton Zmijewski Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
COR Therapeutics Inc
Eli Lilly and Co
Original Assignee
COR Therapeutics Inc
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by COR Therapeutics Inc, Eli Lilly and Co filed Critical COR Therapeutics Inc
Publication of AU2001268162A1 publication Critical patent/AU2001268162A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2001268162A 2000-06-02 2001-06-01 Methods for producing chiral chromones, chromanes, amino substituted chromanes and intermediates therefor Abandoned AU2001268162A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20882700P 2000-06-02 2000-06-02
US60/208,827 2000-06-02
PCT/US2001/017980 WO2001094335A2 (en) 2000-06-02 2001-06-01 Methods for producing chiral chromones, chromanes, amino substituted chromanes and intermediates therefor

Publications (1)

Publication Number Publication Date
AU2001268162A1 true AU2001268162A1 (en) 2001-12-17

Family

ID=22776208

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001268162A Abandoned AU2001268162A1 (en) 2000-06-02 2001-06-01 Methods for producing chiral chromones, chromanes, amino substituted chromanes and intermediates therefor

Country Status (4)

Country Link
US (1) US6756403B2 (en)
EP (1) EP1292589A2 (en)
AU (1) AU2001268162A1 (en)
WO (1) WO2001094335A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001092250A2 (en) * 2000-06-02 2001-12-06 Cor Therapeutics, Inc. Synthesis of 2-acyl substituted chromanes and intermediates thereof
US6867224B2 (en) 2002-03-07 2005-03-15 Warner-Lambert Company Compounds that modulate PPAR activity and methods of preparation
SE0400759D0 (en) * 2004-03-23 2004-03-23 Astrazeneca Ab Novel amination process
SE0400786D0 (en) * 2004-03-25 2004-03-25 Astrazeneca Ab Novel Process for the preparation of a chromone intermediate
CN102977068A (en) * 2012-05-03 2013-03-20 中国药科大学 Nitric oxide donor type isochromanone derivatives, preparation methods and uses thereof
CN105541774B (en) * 2016-01-13 2018-06-15 华中师范大学 3,4- dihydrocoumarin class compounds and its preparation method and application
CN113214205B (en) * 2021-04-09 2022-06-10 南方海洋科学与工程广东省实验室(湛江) Preparation method of chromone derivative

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4026907A (en) 1973-11-19 1977-05-31 Hoffmann-La Roche Inc. Antioxidant chroman compounds
US5731324A (en) 1993-07-22 1998-03-24 Eli Lilly And Company Glycoprotein IIb/IIIa antagonists

Also Published As

Publication number Publication date
EP1292589A2 (en) 2003-03-19
US6756403B2 (en) 2004-06-29
WO2001094335A3 (en) 2002-08-08
WO2001094335A2 (en) 2001-12-13
US20040053992A1 (en) 2004-03-18
WO2001094335A8 (en) 2003-11-06

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